Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Tanja D de Gruijl"'
Autor:
Sandra J. van Vliet, Juan J. Garcia-Vallejo, Sjoerd T.T. Schetters, Martino Ambrosini, Eelco D. Keuning, Rieneke van de Ven, Sophie K. Horrevorts, Sanne Duinkerken, Tanja D. de Gruijl, Hakan Kalay, Laura J.W. Kruijssen, Dorian A. Stolk, Yvette van Kooyk
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss, Pp 315-328 (2021)
Stolk, D A, Horrevorts, S K, Schetters, S T T, Kruijssen, L J W, Duinkerken, S, Keuning, E, Ambrosini, M, Kalay, H, van de Ven, R, Garcia-Vallejo, J J, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2021, ' Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition ', Molecular Therapy-Oncolytics, vol. 21, pp. 315-328 . https://doi.org/10.1016/j.omto.2021.04.009
Molecular Therapy-Oncolytics, 21, 315-328. Nature Publishing Group
Molecular Therapy Oncolytics
Stolk, D A, Horrevorts, S K, Schetters, S T T, Kruijssen, L J W, Duinkerken, S, Keuning, E, Ambrosini, M, Kalay, H, van de Ven, R, Garcia-Vallejo, J J, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2021, ' Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition ', Molecular Therapy-Oncolytics, vol. 21, pp. 315-328 . https://doi.org/10.1016/j.omto.2021.04.009
Molecular Therapy-Oncolytics, 21, 315-328. Nature Publishing Group
Molecular Therapy Oncolytics
Induction of tumor-specific cytotoxic CD8+ T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility complex (MHC) class I molecules by dendritic cells (DCs). To achieve presentation of exogen
Autor:
Latifa Elantak, Iris A. Schulkens, Arjan W. Griffioen, Pauline Touarin, Ulf J. Nilsson, Kitty C. M. Castricum, Tanja D. de Gruijl, Hakon Lefler, Victor L. Thijssen, Roy Heusschen, Lucia Sanjurjo, Ed Aanhane, Rory R. Koenen
Galectins are versatile glycan-binding proteins involved in immunomodulation. Increasing evidence suggests that galectins can control the immunoregulatory function of cytokines and chemokines through direct binding. Here, we report a new inverse mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b52d83da78edd60bbd8a58755ac95ad4
https://doi.org/10.21203/rs.3.rs-275662/v1
https://doi.org/10.21203/rs.3.rs-275662/v1
Autor:
Martino Ambrosini, Sanne Duinkerken, Juan J. Garcia-Vallejo, Tanja D. de Gruijl, Lisa Rutte, Hakan Kalay, Sophie K. Horrevorts, Yvette van Kooyk
Publikováno v:
Duinkerken, S, Horrevorts, S K, Kalay, H, Ambrosini, M, Rutte, L, de Gruijl, T D, Garcia-Vallejo, J J & van Kooyk, Y 2019, ' Glyco-dendrimers as intradermal anti-tumor vaccine targeting multiple skin DC subsets ', Theranostics, vol. 9, no. 20, pp. 5797-5809 . https://doi.org/10.7150/thno.35059
Theranostics, 9, 5797-5809
Theranostics
Theranostics, 9(20), 5797-5809. Ivyspring International Publisher
Theranostics, 9, 20, pp. 5797-5809
Theranostics, 9, 5797-5809
Theranostics
Theranostics, 9(20), 5797-5809. Ivyspring International Publisher
Theranostics, 9, 20, pp. 5797-5809
Contains fulltext : 215802.pdf (Publisher’s version ) (Open Access) The human skin is an attractive anti-tumor vaccination site due to the vast network of dendritic cell (DC) subsets that carry antigens to the draining lymph nodes and stimulate tum
Autor:
Daniel G. Pellicci, Jérôme Le Nours, Sonja Zweegman, Jamie Rossjohn, Jana Vree, Tanja D. de Gruijl, Roeland Lameris, Hans van Vliet, Sergio M. Quiñones-Parra, Dale I. Godfrey, Adam P Uldrich, Scott J. J. Reddiex, Stephanie Gras, Richard W.J. Groen, Stewart K. Richardson, Amy R. Howell, Adam Shahine
Publikováno v:
Nature Cancer, 1(11), 1054-1065. Nature Research
Lameris, R, Shahine, A, Pellicci, D G, Uldrich, A P, Gras, S, Le Nours, J, Groen, R W J, Vree, J, Reddiex, S J J, Quiñones-Parra, S M, Richardson, S K, Howell, A R, Zweegman, S, Godfrey, D I, de Gruijl, T D, Rossjohn, J & van der Vliet, H J 2020, ' A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response ', Nature Cancer, vol. 1, no. 11, pp. 1054-1065 . https://doi.org/10.1038/s43018-020-00111-6
Lameris, R, Shahine, A, Pellicci, D G, Uldrich, A P, Gras, S, Le Nours, J, Groen, R W J, Vree, J, Reddiex, S J J, Quiñones-Parra, S M, Richardson, S K, Howell, A R, Zweegman, S, Godfrey, D I, de Gruijl, T D, Rossjohn, J & van der Vliet, H J 2020, ' A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response ', Nature Cancer, vol. 1, no. 11, pp. 1054-1065 . https://doi.org/10.1038/s43018-020-00111-6
Antibody-mediated modulation of major histocompatibility complex (MHC) molecules, or MHC class I-like molecules, could constitute an effective immunotherapeutic approach. We describe how single-domain antibodies (VHH), specific for the human MHC clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea940a52a04af014f09de68a3955315
https://research.vumc.nl/en/publications/ce8fd044-e1a6-4aa8-993b-5e499a7bf788
https://research.vumc.nl/en/publications/ce8fd044-e1a6-4aa8-993b-5e499a7bf788
Autor:
Dorian A. Stolk, Aram de Haas, Jana Vree, Sanne Duinkerken, Joyce Lübbers, Rieneke van de Ven, Martino Ambrosini, Hakan Kalay, Sven Bruijns, Hans J. van der Vliet, Tanja D. de Gruijl, Yvette van Kooyk
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Stolk, D A, de Haas, A, Vree, J, Duinkerken, S, Lübbers, J, van de Ven, R, Ambrosini, M, Kalay, H, Bruijns, S, van der Vliet, H J, de Gruijl, T D & van Kooyk, Y 2020, ' Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T-and iNKT Cell Responses ', Frontiers in Immunology, vol. 11, 990 . https://doi.org/10.3389/fimmu.2020.00990
Frontiers in Immunology
Frontiers in Immunology, 11:990
Stolk, D A, de Haas, A, Vree, J, Duinkerken, S, Lübbers, J, van de Ven, R, Ambrosini, M, Kalay, H, Bruijns, S, van der Vliet, H J, de Gruijl, T D & van Kooyk, Y 2020, ' Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T-and iNKT Cell Responses ', Frontiers in Immunology, vol. 11, 990 . https://doi.org/10.3389/fimmu.2020.00990
Frontiers in Immunology
Frontiers in Immunology, 11:990
In this study we developed a liposome-based vaccine containing palmitoylated synthetic long peptides (SLP) and alpha galactosylceramide (αGC) to specifically target dendritic cells (DC) for activation of both innate (invariant natural killer T-cells
Autor:
Tanja D. de Gruijl, Niels W.C.J. van de Donk, Paul W. H. I. Parren, Thilo Riedl, Rob C. Roovers, Annemiek Broyl, Roeland Lameris, Iris de Weerdt, Jurjen M. Ruben, Victoria Iglesias, Anton Ep Adang, Benjamin Winograd, Arnon P. Kater, Hans van Vliet
Publikováno v:
Blood. 138:2266-2266
Background. Bispecific antibodies that target tumors by engaging innate-like T cell subsets with inherent antitumor activity, such as Vγ9Vδ2-T and type 1 natural killer T (NKT) cells, may combine high therapeutic efficacy with limited off-tumor tox
Autor:
Dieke van Dinther, Tanja D. de Gruijl, Yvette van Kooyk, Joke M. M. den Haan, Rieneke van de Ven, Dorian A. Stolk
Publikováno v:
van Dinther, D, Stolk, D A, van de Ven, R, van Kooyk, Y, de Gruij, T D & den Haan, J M M 2017, ' Targeting C-type lectin receptors : A high-carbohydrate diet for dendritic cells to improve cancer vaccines ', Journal of Leukocyte Biology, vol. 102, no. 4, pp. 1017-1034 . https://doi.org/10.1189/jlb.5MR0217-059RR
Journal of Leukocyte Biology
Journal of Leukocyte Biology
Review of in vivo targeting of tumor antigens to lectin receptors on antigen-presenting cells using antibodies or ligands may improve the antitumor efficacy of vaccines.
There is a growing understanding of why certain patients do or do not respo
There is a growing understanding of why certain patients do or do not respo
Autor:
Sandra J. van Vliet, Sophie A. Dusoswa, Juan J. Garcia-Vallejo, Rienk Nieuwland, Dorian A. Stolk, Rieneke van de Ven, Sanne Duinkerken, Arjan A. van de Loosdrecht, Bert van het Hof, Sophie K. Horrevorts, Myrthe Hulst, Yvette van Kooyk, Marieke H. Heineke, Wenbin Ma, Tanja D. de Gruijl
Publikováno v:
Cancers, 11(9):1266. Multidisciplinary Digital Publishing Institute (MDPI)
Horrevorts, S K, Stolk, D A, van de Ven, R, Hulst, M, van Het Hof, B, Duinkerken, S, Heineke, M H, Ma, W, Dusoswa, S A, Nieuwland, R, Garcia-Vallejo, J J, van de Loosdrecht, A A, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2019, ' Glycan-modified melanoma-derived apoptotic extracellular vesicles as antigen source for anti-tumor vaccination ', Cancers, vol. 11, no. 9, 1266 . https://doi.org/10.3390/cancers11091266
Cancers
Volume 11
Issue 9
Horrevorts, S K, Stolk, D A, van de Ven, R, Hulst, M, van Het Hof, B, Duinkerken, S, Heineke, M H, Ma, W, Dusoswa, S A, Nieuwland, R, Garcia-Vallejo, J J, van de Loosdrecht, A A, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2019, ' Glycan-modified melanoma-derived apoptotic extracellular vesicles as antigen source for anti-tumor vaccination ', Cancers, vol. 11, no. 9, 1266 . https://doi.org/10.3390/cancers11091266
Cancers
Volume 11
Issue 9
Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of anti-tumor T cell responses. An attractive vaccine strategy is in vivo targeting of dendri
Autor:
Martino Ambrosini, Cynthia M. Fehres, Sven C. M. Bruijns, W.W.J. Unger, Sanne Duinkerken, Tanja D. de Gruijl, Yvette van Kooyk, Hakan Kalay, Sandra J. van Vliet, Juan J. Garcia-Vallejo
Publikováno v:
Fehres, C M, Duinkerken, S, Bruijns, S C, Kalay, H, van Vliet, S J, Ambrosini, M, de Gruijl, T D, Unger, W W, Garcia-Vallejo, J J & van Kooyk, Y 2017, ' Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells ', Cellular Immunology, vol. 14, no. 4, pp. 360-370 . https://doi.org/10.1038/cmi.2015.87
Cellular Immunology, 14(4), 360-370. Academic Press Inc.
Cellular Immunology, 14(4), 360-370. Academic Press Inc.
The potential of the skin immune system to generate immune responses is well established, and the skin is actively exploited as a vaccination site. Human skin contains several antigen-presenting cell subsets with specialized functions. In particular,
Autor:
Tanja D. de Gruijl, Theresia M. Westers, Malin Lindstedt, Kristina Lundberg, Arjan A. van de Loosdrecht, Shahram Kordasti, Hetty J. Bontkes, Nathalie van Leeuwen-Kerkhoff
Publikováno v:
van Leeuwen-Kerkhoff, N, Lundberg, K, Westers, T M, Kordasti, S, Bontkes, H J, de Gruijl, T D, Lindstedt, M & van de Loosdrecht, A A 2017, ' Transcriptional profiling reveals functional dichotomy between human slan + non-classical monocytes and myeloid dendritic cells ', Journal of Leukocyte Biology, vol. 102, no. 4, pp. 1055-1068 . https://doi.org/10.1189/jlb.3MA0117-037R
Journal of Leukocyte Biology, 102(4), 1055-1068. FASEB
Journal of Leukocyte Biology, 102(4), 1055-1068. FASEB
Human 6-sulfo LacNac-positive (slan+) cells have been subject to a paradigm debate. They have previously been classified as a distinct dendritic cell (DC) subset. However, evidence has emerged that they may be more related to monocytes than to DCs. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cc365d54d0dd0ac24aeb58f3b0a675
https://research.vumc.nl/en/publications/c4623abe-0cb6-45e2-9bd4-6323c053641d
https://research.vumc.nl/en/publications/c4623abe-0cb6-45e2-9bd4-6323c053641d