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Autor:
Xiaoli Xiong, Steven J. Gamblin, Jie Zhang, Sébastien G. Vachieri, Stephen R. Martin, John J. Skehel
Publikováno v:
Cold Spring Harbor perspectives in medicine. 11(10)
Hemagglutinins (HAs) are the receptor-binding and membrane fusion glycoproteins of influenza viruses. They recognize sialic acid-containing, cell-surface glycoconjugates as receptors but have limited affinity for them, and, as a consequence, virus at
Publikováno v:
Antioxidantsredox signaling. 37(7-9)
SIGNIFICANCE Reactive oxygen species (ROS) contribute to multiple aspects of peripheral nervous system (PNS) biology ranging from physiological processes (e.g. axonal outgrowth and regeneration), to pathophysiology (e.g. nerve degeneration). Although
Autor:
Maria G. Masucci
Publikováno v:
Seminars in Cell & Developmental Biology. 132:185-192
The covalent attachment of ubiquitin and ubiquitin-like polypeptides to cellular and viral proteins regulates numerous processes that enable virus infection, viral genome replication, and the spread of viruses to new hosts. The importance of these pr
Autor:
Jae-Hyun Lee, Chang-Min Lee, Joyce H. Lee, Mun-Ock Kim, Jin Wook Park, Suchitra Kamle, Bedia Akosman, Erica L. Herzog, Xue Yan Peng, Jack A. Elias, Chun Geun Lee
Publikováno v:
Am J Respir Cell Mol Biol
RationalePulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Facto
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156754 (2016)
PLoS ONE
PLoS ONE
Drug delivery to tumors is limited by several factors, including drug permeability of the target cell plasma membrane. Ultrasound in combination with microbubbles (USMB) is a promising strategy to overcome these limitations. USMB treatment elicits en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1631bc38b0cb0560e30b7a6b9ff17f
https://doi.org/10.32920/14638422
https://doi.org/10.32920/14638422
Autor:
Lauren Schaff, Christian Grommes
Publikováno v:
Blood. 140:971-979
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphomatous malignancy that affects the brain, spinal cord, leptomeninges, or vitreoretinal space, without evidence of systemic involvement. The diagnosis of PCNSL requires a high
Autor:
Michael Lehrke, Pascal Alexander Mann
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 164:895-899
Publikováno v:
Seminars in Cancer Biology. 83:88-99
Methylation is a major post-translational modification (PTM) generated by methyltransferase on target proteins; it is recognized by the epigenetic reader to expand the functional diversity of proteins. Methylation can occur on specific lysine or argi
Autor:
Snehasis Jana, Trupti Gohil, Upendra P. Lambe, Shyam Sundar Nandi, Sonali Ankush Sawant, Sudip Ghosh
Publikováno v:
Current Molecular Medicine. 22:594-607
Cluster of differentiation (CD155), formerly identified as poliovirus receptor (PVR) and later as immunoglobulin molecule, is involved in cell adhesion, proliferation, invasion and migration. It is a surface protein expressed mostly on normal and tra
Publikováno v:
Blood
As the coronavirus disease (COVID-19) pandemic led to a global health crisis, there were limited treatment options and no prophylactic therapies for those exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Convalescent plasma is