Zobrazeno 1 - 10
of 16 128
pro vyhledávání: ''
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156754 (2016)
PLoS ONE
PLoS ONE
Drug delivery to tumors is limited by several factors, including drug permeability of the target cell plasma membrane. Ultrasound in combination with microbubbles (USMB) is a promising strategy to overcome these limitations. USMB treatment elicits en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1631bc38b0cb0560e30b7a6b9ff17f
https://doi.org/10.32920/14638422
https://doi.org/10.32920/14638422
Autor:
Augustine M.K. Choi, Mi-Ae Park, Mijin Yun, Chun K. Kim, Kiichi Nakahira, Jong Seok Moon, Maria Haslip, Ilias I. Siempos, Judie A. Howrylak, Patty J. Lee, Seonmin Lee, Stefan W. Ryter
Publikováno v:
Journal of Clinical Investigation. 133
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1–depen
Autor:
George C.T. Yeoh, David L. Vaux, Paul G Ekert, James E Vince, Joanne H. van Vuuren, Megan Finch-Edmondson, Bernard A. Callus, Katharine J. Goodall, Ian E Gentle
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164003 (2016)
PLoS ONE
PLoS ONE
Apoptosis mediated by Bax or Bak is usually thought to be triggered by BH3-only members of the Bcl-2 protein family. BH3-only proteins can directly bind to and activate Bax or Bak, or indirectly activate them by binding to anti-apoptotic Bcl-2 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c6cc591fdc88f2734d87e3bff47b7d
Autor:
Paul M. Daniel, Frédéric Hollande, Andrew P. Morokoff, Gulay Filiz, Sebastian Dworkin, Theo Mantamadiotis, Daniel Brown, Wayne Ng, Nicole Kountouri, Stephanie Amiridis
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172791 (2017)
PLoS ONE, Vol 12, Iss 2, p e0172791 (2017)
Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinct GBM molecular subtypes that respond differently to ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93541fc9763c8c99c234f613764a359
Publikováno v:
Journal of Healthcare Engineering
Journal of Healthcare Engineering, Vol 2022 (2022)
Journal of Healthcare Engineering, Vol 2022 (2022)
Objectives. To investigate the effect of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and its molecular mechanism. Methods. After TSG treatment of rBMSCs, alk
Publikováno v:
Bioengineered, Vol 13, Iss 1, Pp 164-177 (2022)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Angiogenesis plays an important role in tissue development and repair, and how to regulate angiogenesis effectively is a widely studied problem in the biomedical field. In recent years, the role of autophagy in vascular endothelial cells has attracte
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 13, Iss 1, Pp 407-417 (2022)
article-version (VoR) Version of Record
Bioengineered, Vol 13, Iss 1, Pp 407-417 (2022)
Dysregulated lipid metabolism of macrophages contributes to thrombosis and antiphospholipid syndrome (APS). The long non-coding RNAs (lncRNA) myocardial infarction-associated transcript 2 (Mirt2) has been reported to inhibit inflammation and lipid ac
Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 9484-9495 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Linc00467 is a vital regulator in tumor progression. This study explores the molecular mechanisms of linc00467 in gastric cancer (GC). Linc00467 expression was obtained and analyzed in GC tissue through exploration in the cancer genome atlas database
Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 9463-9472 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Vascular smooth muscle cell (VSMC) hyperplasia is closely associated with AS progression. Hence, it is of great significance to elucidate the molecular mechanisms underlying the involvement of VSMCs in AS. SHH antagonist can inhibit the excessive pro
Autor:
Michael M. Myerburg, Mads Breum Larsen, Raymond A. Frizzell, Jeannie J Choi, Carol A. Bertrand, Xiaohui Wang
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Aberrant anion secretion across the bronchial epithelium is associated with airway disease, most notably in cystic fibrosis. Although the cystic fibrosis transmembrane conductance regulator (CFTR) is recognized as the primary source of airway anion s