Zobrazeno 71 - 80
of 14 694
pro vyhledávání: ''
Autor:
Ying Yan, Wenju Chen, Yueyin Pan, Jiayu Niu, Hui-qin Luo, Shusheng Wu, Yifu He, Huimin Li, Huijun Xu, Lulu Cao, Xiaoxiu Hu, Lihong Ke
Publikováno v:
Journal of Cellular and Molecular Medicine
Previous studies have indicated that centromere protein K (CENPK) is upregulated in several cancers and related to tumorigenesis. Nevertheless, the potential function of CENPK in gastric cancer (GC) remains unknown. Here, we investigated the function
Publikováno v:
Biochemical and Biophysical Research Communications. 567:183-189
Colon cancer is a common human cancer worldwide. The survival rate of late staged or metastatic colon cancer patients remains low even though the effectiveness of treatment in colon cancer has greatly improved. Research on tumorigenesis mechanisms an
Publikováno v:
DNA and Cell Biology. 40:1101-1111
Chronic myeloid leukemia (CML) is characterized by the formation of the BCR-ABL fusion gene. The BCR-ABL protein leads to an increased level of reactive oxygen species, which is a major cause of endogenous DNA double-strand breaks (DSBs). CML cells a
Publikováno v:
Aging (Albany NY)
CircRNAs have emerged as potential therapeutic targets for diseases such as gastric cancer (GC). We identified highly dysregulated circRNAs in GC tissue and further explored their potential mechanisms in the progression of GC. Hsa_circ_0091994 (cicrR
Autor:
Amin Reza Nikpoor, Fateme Zare, Houshang Rafatpanah, Farzaneh Fesahat, Hossein Hadinedoushan, Mahmoud Reza Jaafari, Mojtaba Sankian, Mohammad Taher Tahoori, Mahdi Dehghan-Manshadi
Publikováno v:
Biochemistry and Cell Biology. 99:435-446
This study compared the prophylactic effects from vaccines based on dendritic cells (DCs) and peripheral blood mononuclear cells (PBMCs) by pulsing the cells in-vitro with p5 peptide. The different test groups of mice were injected with free peptide
Publikováno v:
Aging (Albany NY)
Background: Enhanced infiltration of M2-polarized tumor-associated macrophages (TAMs) is linked to osteosarcoma (OS) metastasis and growth. Here, we aim to explore a novel miR-221-3p shuttled by M2-TAM exosomes in the growth and metastasis of OS cell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports, Vol. 11, p. 17346 (2021)
Scientific Reports
Scientific Reports, Vol. 11, p. 17346 (2021)
DNA methylation is an epigenetic mark associated with gene repression. It is now well established that tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) of met
Publikováno v:
Cell Biology International. 45:2129-2139
Colon adenocarcinoma (COAD) is the commonest type of colorectal cancer with high morbidity and mortality worldwide. ETS variant 4 (ETV4) is a member of the ETS transcription factors and is frequently involved in the progression of many cancers. This
Publikováno v:
Cell Cycle
Piwi-interacting RNAs (piRNAs/piRs) are small non-coding RNAs that play important roles in stablizing genome through silencing transposable genetic elements. The piR-651 was reported to be dysregulated in several human solid cancer tissues, such as g
Publikováno v:
Journal of Pharmacy and Pharmacology. 73:1397-1404
Objectives Tonkinensine B, a novel compound with cytisine–pterocarpan skeleton isolated from the root of Sophora tonkinensis Gagnep, was reported to have a significant antitumor effect. The effect and intrinsic mechanism of tonkinensine B on tumour