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Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 9484-9495 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Linc00467 is a vital regulator in tumor progression. This study explores the molecular mechanisms of linc00467 in gastric cancer (GC). Linc00467 expression was obtained and analyzed in GC tissue through exploration in the cancer genome atlas database
Publikováno v:
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology, Vol 2021 (2021)
Analytical Cellular Pathology, Vol 2021 (2021)
Hypoxia is a typical microenvironment feature in almost all solid tumors and is frequently associated with growth of cancers including colorectal cancer (CRC). This study focuses on the influence of hypoxic microenvironment on the activity of CRC cel
Autor:
Da Bin Kim, Myung-Shin Lee, Hong Seok Kim, Haeun Ko, Seung Ro Han, Jisu Lee, Yun Hee Kang, Seyoun Park
Publikováno v:
Molecules and Cells
Hypoxia, or low oxygen tension, is a hallmark of the tumor microenvironment. The hypoxia-inducible factor-1α (HIF-1α) subunit plays a critical role in the adaptive cellular response of hypoxic tumor cells to low oxygen tension by activating gene-ex
Publikováno v:
Molecules and Cells
As a pancreatic inflammatory marker, regenerating islet-derived protein 3A (Reg3A) plays a key role in inflammation-associated pancreatic carcinogenesis by promoting cell proliferation, inhibiting apoptosis, and regulating cancer cell migration and i
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Aspirin eugenol ester (AEE) is a new pharmaceutical compound esterified by aspirin and eugenol, which has anti-inflammatory, antioxidant, and other pharmacological activities. The aim of this study was to investigate the protective effect of AEE on p
Autor:
Kaiyun Gu, Hongchi Yu, Jia He, Guanyue Su, Xiaoheng Liu, Wenxing Yang, Fei Fang, Yang Shen, Naiyang Fu, Yunbing Wang, Yuelong Wang
Publikováno v:
Molecular Oncology
Epithelial–mesenchymal transition (EMT) mediated by fluid shear stress (FSS) in the tumor microenvironment plays an important role in driving metastasis of the malignant tumor. As a mechanotransducer, Yes‐associated protein (YAP) is known to tran
Autor:
Yih Giun Cherng, Oluwaseun Adebayo Bamodu, Shiue Wei Lai, Ming Yao Chen, Chi Tai Yeh, Ming Shou Hsieh, Ting Yi Huang, Wei Hwa Lee
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Background. Treating advanced colon cancer remains challenging in clinical settings because of the development of drug resistance and distant metastasis. Mechanisms underlying the metastasis of colon cancer are complex and unclear. Methods. Computati
Publikováno v:
Molecules and Cells
Cyclase-associated protein 2 (CAP2) has been addressed as a candidate biomarker in various cancer types. Previously, we have shown that CAP2 is expressed during multi-step hepatocarcinogenesis; however, its underlying mechanisms in liver cancer cells
Autor:
Oudart, Jean-Baptiste, Villemin, Matthieu, Brassart, Bertrand, Sellier, Christèle, Terryn, Christine, Dupont-Deshorgue, Aurélie, Monboisse, Jean Claude, Maquart, François-Xavier, Ramont, Laurent, Brassart-Pasco, Sylvie, Monboisse, Jean
Publikováno v:
Cell Adhesion & Migration
article-version (VoR) Version of Record
Cell Adhesion and Migration
Cell Adhesion and Migration, Taylor & Francis, 2021, 15 (1), pp.215-223. ⟨10.1080/19336918.2021.1951425⟩
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 215-223 (2021)
article-version (VoR) Version of Record
Cell Adhesion and Migration
Cell Adhesion and Migration, Taylor & Francis, 2021, 15 (1), pp.215-223. ⟨10.1080/19336918.2021.1951425⟩
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 215-223 (2021)
International audience; We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 7, Pp 1835-1848 (2021)
Molecular Oncology, Vol 15, Iss 7, Pp 1835-1848 (2021)
Tumor cells invade and spread via either a mesenchymal or an amoeboid mode of migration. Amoeboid tumor cells have a rounded morphology and pronounced RhoA activity. Here, we investigate how WNT5A signaling, a tumor promotor in melanoma, relates to R