Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sergio Valente"'
Autor:
Licheng Zhu, Wenhu Duan, Jinrong Min, Kongkai Zhu, Shijie Fan, Giulia Stazi, Clemens Zwergel, Xiangqian Kong, Hualiang Jiang, Kaiyan Zhao, Daohai Du, Yuanqing Li, Naixia Zhang, Yuanyuan Zhang, Yanli Liu, Kehao Zhao, Sergio Valente, Zhongyuan Luo, Yiluan Ding, Dandan Xu, Jingqiu Liu, Cheng Luo, Kaixian Chen
Disruption of EZH2-embryonic ectoderm development (EED) protein-protein interaction (PPI) is a new promising cancer therapeutic strategy. We have previously reported the discovery of astemizole, a small-molecule inhibitor targeting the EZH2-EED PPI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7769f96723b0c2c58a9cf6ad8b9e50a
http://hdl.handle.net/11573/1550470
http://hdl.handle.net/11573/1550470
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 8 (2020)
Frontiers in Chemistry, Vol 8 (2020)
Numerous and different types of cancers possess the dysregulation of the mevalonate pathway as a common feature. Statins, traditionally applied in cardiovascular diseases to reduce lipid levels, subsequently have been discovered to exhibit anti-cance