Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas S. Uldrick"'
Autor:
Amrit Singh, Anthony P. Schwarer, Helen L. Partridge, Frits van Rhee, Daniel J. Arenas, David C. Fajgenbaum, Katie L. Stone, Mariko Okumura, Jason R. Ruth, Nelson Hamerschlak, Michael R. Betts, Thomas S. Uldrick, Gerald Wertheim, Christopher S. Nabel, Taku Kambayashi, Michael B. Jordan, Sheila K Pierson, Fabio Freire José, Alberto Sada Japp, Arthur H. Rubenstein, Adam D. Cohen, Ruth-Anne Langan, Vera P. Krymskaya
Publikováno v:
Journal of Clinical Investigation. 129:4451-4463
BACKGROUND Idiopathic multicentric Castleman disease (iMCD) is a hematologic illness involving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening multi-organ dysfunction. The molecular underpinnings of inter
Publikováno v:
Curr HIV/AIDS Rep
PURPOSE OF REVIEW: Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) pathway are a class of anti-cancer immunotherapy agents changing treatment paradigms of many cancers that occur at higher rates in people living with HIV (PL
Autor:
Thomas S. Uldrick, Drew Pratt
Publikováno v:
Blood. 127(23)
[Figure][1] A 59-year-old man was diagnosed with HIV and Kaposi sarcoma (KS) 8 years prior to death; CD4+ count at diagnosis was 538 cells per μL. Despite antiretroviral therapy, KS required several additional therapies. More than 7 years later, the
Autor:
Seth M. Steinberg, Mark N. Polizzotto, Richard F. Little, Thomas S. Uldrick, Vickie Marshall, Kathleen M. Wyvill, Robert Yarchoan, Deirdre O'Mahony, Karen Aleman, Denise Whitby, Stefania Pittaluga, Victoria Wang, Giovanna Tosato
Publikováno v:
Blood. 122(26)
Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder. Human (h) IL-6 and a KSHV-encoded homolog, viral IL-6, have been hypothesized to contribute to its pathogenesis, bu
Publikováno v:
Frontiers in Microbiology, Vol 3 (2012)
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus. I
Autor:
Victoria Wang, Giovanna Tosato, Kathleen M. Wyvill, Mark N. Polizzotto, Stefania Pittaluga, Seth M. Steinberg, Robert Yarchoan, Denise Whitby, Thomas S. Uldrick, Vickie Marshall, Karen Aleman, Richard F. Little, Dierdre O'Mahony
Publikováno v:
Infectious Agents and Cancer, Vol 5, Iss Suppl 1, p A47 (2010)
Infectious Agents and Cancer
Infectious Agents and Cancer
KSHV activation, human and viral IL-6 production, and other cytokine dysregulation: Association with the symptomatology of KSHV-associated multicentric Castleman’s disease Mark N Polizzotto, Thomas S Uldrick, Victoria Wang, Karen Aleman, Kathleen M
Autor:
Giovanna Tosato, Armando C. Filie, Adam Rupert, Stefania Pittaluga, Richard F. Little, Mark N. Polizzotto, Kathleen M. Wyvill, Priscila H. Goncalves, Karen Aleman, Manisha Bhutani, Seth M. Steinberg, Vickie Marshall, Denise Whitby, Robert Yarchoan, Thomas S. Uldrick
Publikováno v:
Blood. 124:3001-3001
Introduction: Primary effusion lymphoma (PEL) and large cell lymphoma arising in Kaposi sarcoma-associated herpesvirus associated multicentric Castleman disease (KSHV-MCD) are KSHV-associated non-Hodgkin lymphomas (together, KSHV-NHL) with overlappin
Autor:
Cody J. Peer, Mark N. Polizzotto, Thomas S. Uldrick, Kathleen M. Wyvill, William D. Figg, David Venzon, Richard F. Little, Wendy B. Bernstein, Karen Aleman, Stefania Pittaluga, Deirdre O'Mahony, Seth M. Steinberg, Robert Yarchoan
Publikováno v:
Journal of Clinical Oncology. 31:10588-10588
10588 Background: Kaposi sarcoma (KS) is a multifocal angioproliferative disorder. VEGFR2-3, PDGFR and c-kit are implicated in KS pathogenesis and inhibited by sorafenib (So). KS is commonly HIV-associated. The antiretroviral drug ritonavir (R) inhib
Autor:
Richard F. Little, Stefania Pittaluga, Robert Yarchoan, Vickie Marshall, Victoria Wang, Giovanna Tosato, Mark N. Polizzotto, Deirdre O'Mahony, Karen Aleman, Denise Whitby, Seth M. Steinberg, Thomas S. Uldrick, Kathleen M. Wyvill
Publikováno v:
Blood. 118:1573-1573
Abstract 1573 Background: Multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder characterized by flares of severe inflammatory symptoms, including fever and cachexia, with cytopenias and biochemical abnormalities. I
Autor:
Armando C. Filie, Denise Whitby, Stefania Pittaluga, Richard F. Little, Mark Raffeld, Vickie Marshall, Kathleen M. Wyvill, Karen Aleman, Thomas S. Uldrick, Robert Yarchoan, Seth M. Steinberg, Mark N. Polizzotto
Publikováno v:
Infectious Agents and Cancer
Infectious Agents and Cancer, Vol 7, Iss Suppl 1, p P39 (2012)
Infectious Agents and Cancer, Vol 7, Iss Suppl 1, p P39 (2012)
Background KSHV, also called human herpesvirsus-8 (HHV8), is the etiologic agent of primary effusion lymphoma (PEL) (including extracavitary variant), and large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease (together, KSHV