Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory B Lesinski"'
Autor:
Xueliang Pan, Gregory B. Lesinski, Jeffrey Schlom, Renee N. Donahue, Thomas Olencki, Jacob Richards, Taylor R. Brooks, Volodymyr Karpa, Bonnie Paul, William E. Carson, Caroline Jochems, Megan C. Duggan, Elizabeth Foust, Susheela Tridandapani
Publikováno v:
Cancer Immunology, Immunotherapy. 65:1353-1364
Prime-boost vaccination with recombinant (r) vaccinia(V)-CEA(6D)-TRICOM (triad of co-stimulatory molecules B7.1, ICAM-1 and LFA-3) and rFowlpox(F)-CEA(6D)-TRICOM infect antigen-presenting cells and direct expression of co-stimulatory molecules. We hy
Autor:
Tanios Bekaii-Saab, Jon P. Walker, Walter J. Coyle, Mark Bloomston, Gregory B. Lesinski, Lawrence A. Shirley, Christopher L. Marsh, Daniel Sanchez, Estuardo Aguilar-Cordova, Andrea G. Manzanera, Howard Marx, Vincent Chung, Laura K. Aguilar, Benjamin Swanson
Publikováno v:
Cancer Immunology, Immunotherapy. 64:727-736
While surgical resection of pancreatic adenocarcinoma provides the only chance of cure, long-term survival remains poor. Immunotherapy may improve outcomes, especially as adjuvant to local therapies. Gene-mediated cytotoxic immunotherapy (GMCI) gener
Autor:
Susan N. Thomas, Brian Pollack, Gregory B. Lesinski, Yun Min Chang, Maiko Sasaki, Edmund K. Waller, Anna E. Kersh, Haydn T. Kissick, Spencer Ng, Ragini R. Kudchadkar
Publikováno v:
Journal of clinical pharmacology. 58(1)
Two pharmacologic approaches that are currently at the forefront of treating advanced cancer are those that center on disrupting critical growth/survival signaling pathways within tumor cells (commonly referred to as "targeted therapies") and those t
Autor:
Lauren Dennison, Matthew R. Farren, Gregory B. Lesinski, Amanda Ruggieri, Bassel El-Reyes, Mark Yarchoan, Nilofer S. Azad
Publikováno v:
Cancer Research. 79:3971-3971
Cholangiocarcinoma (CC) is a rare but aggressive cancer of the bile ducts with a five-year survival rate of only 2% in patients with metastatic disease. MAP kinase signaling is important in the pathogenesis of CC and serves as a key regulator of cell
Autor:
Brian D. Badgwell, Tim Crespin, Yan Hu, William E. Carson, Gerard Abood, Jason M. Zimmerer, Gregory B. Lesinski
Publikováno v:
Scopus-Elsevier
IFN-alpha 2b (IFN-alpha) has been used to treat patients with metastatic malignant melanoma and patients rendered disease-free via surgery but at high risk for recurrence. We hypothesized that IL-12 pretreatments would result in endogenous IFN-gamma