Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Philip Brownridge"'
Autor:
Jeff W. Barclay, Claire E. Eyers, Alan Morgan, Kimberley Burrow, Richard Campion, Patricia Thomas, Philip Brownridge, Leanne Bloxam, Campbell W. Gourlay, Daniel R Pentland
Publikováno v:
Biochemical Journal
BIOCHEMICAL JOURNAL
BIOCHEMICAL JOURNAL
Dietary restriction (DR) has been shown to increase lifespan in organisms ranging from yeast to mammals. This suggests that the underlying mechanisms may be evolutionarily conserved. Indeed, upstream signalling pathways, such as TOR, are strongly lin
Autor:
Natalie I Koch, Robert J. Beynon, Catarina Franco, Jane L. Hurst, Helen L. Bayram, Amy J. Claydon, Philip Brownridge, Paula Stockley
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Sperm competition theory predicts that males should tailor ejaculates according to their social status. Here, we test this in a model vertebrate, the house mouse ( Mus musculus domesticus ), combining experimental data with a quantitative proteomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210d3e81807cd2ebab32f5a2f5e994bd
Autor:
Lynn McLean, Pisut Pongchaikul, Margaret Hughes, Robert J. Beynon, John Kenny, Ian Goodhead, Ritesh Krishna, Philip Brownridge, Alistair C. Darby, Frances Blow
Publikováno v:
Microbial Genomics
The majority of bacterial genomes have high coding efficiencies, but there are some genomes of intracellular bacteria that have low gene density. The genome of the endosymbiont Sodalis glossinidius contains almost 50 % pseudogenes containing mutation
Autor:
Leandro Xavier Neves, Claire E. Eyers, Ricardo DeMarco, Victoria M. Harman, Robert J. Beynon, William Castro-Borges, Stephen W. Holman, R. Alan Wilson, Philip Brownridge
Publikováno v:
JOURNAL OF PROTEOME RESEARCH
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Schistosomes are blood-dwelling helminth parasites that cause schistosomiasis, a debilitating disease resulting in inflammation and, in extreme cases, multiple organ damage. Major challenges to control the transmission persist, and the discovery of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e24be4c18488e656da1fd7ede9a0a3
http://livrepository.liverpool.ac.uk/3070612/1/20191109_Manuscript-revised.pdf
http://livrepository.liverpool.ac.uk/3070612/1/20191109_Manuscript-revised.pdf
Autor:
Alistair C. Darby, John Kenny, Robert J. Beynon, Frances Blow, Lynn McLean, Ian Goodhead, Ritesh Krishna, Pisut Pongchaikul, Margaret Hughes, Philip Brownridge
The majority of bacterial genomes have high coding efficiencies, but there are some genomes of intracellular bacteria that have low gene density. The genome of the endosymbiont Sodalis glossinidius contains almost 50% pseudogenes containing mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a34f69f0aa66479259265a8d2ae58a7
Autor:
Matthew A.G. Owen, Simon J. Davies, Phillip D. Whitfield, Iain S. Young, Philip Brownridge, Mary K. Doherty
Publikováno v:
Journal of Proteomics. 75(14):4471-4477
In order to study the protein dynamics in the tissues of fish we have developed a proteomics-based strategy to determine the rates of synthesis and degradation of individual proteins. We have demonstrated the feasibility of this approach by measuring
Autor:
Philip Brownridge, Ronan O’Cualain, Robert J. Beynon, Rachel H. Watkins, Karin Lanthaler, Chris M. Grant, Simon J. Hubbard, Simon J. Gaskell, Stephen W. Holman, Paul F. G. Sims, Craig Lawless, Victoria M. Harman
Publikováno v:
PROTEOMICS. 11:2957-2970
In this paper, we discuss the challenge of large-scale quantification of a proteome, referring to our programme that aims to define the absolute quantity, in copies per cell, of at least 4000 proteins in the yeast Saccharomyces cerevisiae. We have ba
Autor:
Victoria M. Harman, Karin Lanthaler, Craig Lawless, Chris M. Grant, Aishwarya Payapilly, Robert J. Beynon, Simon J. Hubbard, Philip Brownridge, Stephen W. Holman
Publikováno v:
Brownridge, P, Lawless, C, Payapilly, A B, Lanthaler, K, Holman, S W, Harman, V M, Grant, C M, Beynon, R J & Hubbard, S J 2013, ' Quantitative analysis of chaperone network throughput in budding yeast ', Proteomics, vol. 13, no. 8, pp. 1276-1291 . https://doi.org/10.1002/pmic.201200412
Proteomics
Proteomics
The network of molecular chaperones mediates the folding and translocation of the many proteins encoded in the genome of eukaryotic organisms, as well as a response to stress. It has been particularly well characterised in the budding yeast, Saccharo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7438d381d5c5bf8c4234e776edb64a4f
https://research.manchester.ac.uk/en/publications/b23183e7-e584-4f08-a89f-a2e47114ec17
https://research.manchester.ac.uk/en/publications/b23183e7-e584-4f08-a89f-a2e47114ec17
Autor:
Andrew R. Cossins, Luciane V. Mello, M. Peters, Philip Brownridge, Phillip D. Whitfield, Iain S. Young, Amy J. Claydon, Lynn McLean
Publikováno v:
The Journal of experimental biology. 212(Pt 2)
SUMMARYThe mechanical properties of the axial muscles vary along the length of a fish's body. This variation in performance correlates with the expression of certain muscle proteins. Parvalbumin (PARV) is an important calcium binding protein that hel
Autor:
Simon J. Gaskell, Robert J. Beynon, Claire E. Eyers, Catherine L. Winder, Naglis Malys, Stephen G. Oliver, Douglas B. Kell, Philip Brownridge, Karin Lanthaler, Christopher Knight, Pınar Pir, Deborah M. Simpson, Kathleen M. Carroll, Warwick B. Dunn
Publikováno v:
Molecular & Cellular Proteomics. 10:M111.007633
The availability of label-free data derived from yeast cells (based on the summed intensity of the three strongest, isoform-specific peptides) permitted a preliminary assessment of protein abundances for glycolytic proteins. Following this analysis,