Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miloje Savic"'
Autor:
Kellie Vinal, Miloje Savic, Rachel Macmaster, Natalia Zelinskaya, S. Sunita, Graeme L. Conn, Pooja M. Desai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:2807-2816
Methylation of bacterial 16S rRNA within the ribosomal decoding center confers exceptionally high resistance to aminoglycoside antibiotics. This resistance mechanism is exploited by aminoglycoside producers for self-protection while functionally equi
Publikováno v:
Archives of Biological Sciences, Vol 62, Iss 3, Pp 559-564 (2010)
Ramonda serbica and Ramonda nathaliae, rare resurrection plants growing in the Balkan Peninsula, produce a high amount of phenolic compounds as a response to stress. The composition and size of bacterial communities in two rhizosphere soil samples of
Publikováno v:
Nucleic Acids Research
The 16S ribosomal RNA methyltransferase enzymes that modify nucleosides in the drug binding site to provide self-resistance in aminoglycoside-producing micro-organisms have been proposed to comprise two distinct groups of S-adenosyl-l-methionine (SAM
High-level resistance to a broad spectrum of aminoglycoside antibiotics can arise through either N7-methyl guanosine 1405 (m7G1405) or N1-methyl adenosine 1408 (m1A1408) modifications at the drug binding site in the bacterial 30S ribosomal subunit de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a5be49b039ebec3af348ae6d3c6847
https://europepmc.org/articles/PMC2966526/
https://europepmc.org/articles/PMC2966526/
Autor:
Miloje Savic, Ivana Moric, Branka Vasiljevic, Sanja Bajkic, Tatjana Ilic Tomic, Graeme L. Conn
Publikováno v:
The protein journal. 28(7-8)
The mechanism of resistance to aminoglycosides based on methylation of their target, 16S rRNA, was until recently described only in antibiotic producing microorganisms. However, equivalent methyltransferases have now also been identified among numero
Publikováno v:
Journal of bacteriology. 190(17)
The 16S rRNA methyltransferase Sgm from “ Micromonospora zionensis ” confers resistance to aminoglycoside antibiotics by specific modification of the 30S ribosomal A site. Sgm is a member of the FmrO family, distant relatives of the S -adenosyl-
Publikováno v:
International journal of systematic and evolutionary microbiology. 57(Pt 9)
Screening of soil samples from the Durmitor National Park, Serbia and Montenegro, for strains producing immunosuppressants with a similar mechanism of action to FK506 resulted in the isolation of the actinomycete strain MS405T. Isolate MS405T was fou
Autor:
Branka Vasiljevic, Miloje Savic
Publikováno v:
Journal of industrial microbiologybiotechnology. 33(6)
Natural products provide a unique element of molecular diversity and biological functionality and they are still indispensable for drug discovery. The polyketides, comprising a large and structurally diverse family of bioactive natural products, have
Autor:
Branka Vasiljevic, Natasa Skoko, Natasa Papic, Goran Ljubijankic, Miloje Savic, Jelena Vujovic
Publikováno v:
Journal of microbiological methods. 61(1)
The screening of microbial natural products continues to represent an important route to the discovery of novel chemicals for development of new therapeutic agents. The aim of this work was to develop an efficient method for the detection of immunosu