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Publikováno v:
Journal of Biological Chemistry. 279:27855-27860
The Gal4p family of yeast zinc cluster proteins comprises regulators of multidrug resistance genes. For example, Pdr1p and Pdr3p bind as homo- or heterodimers to pleiotropic drug response elements (PDREs) found in promoters of target genes. Other zin
Autor:
Martine Raymond, Sandra Weber, Bernard Turcotte, Sarah MacPherson, Bassel Akache, Xavier De Deken
Publikováno v:
Antimicrobial agents and chemotherapy. 49(5)
The human pathogen Candida albicans is responsible for a large proportion of infections in immunocompromised individuals, and the emergence of drug-resistant strains is of medical concern. Resistance to antifungal azole compounds is often due to an i