Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rabia Hussain"'
Autor:
Nawal Salahuddin, Nisar Rao, Zahra Hasan, Mussarat Ashraf, Rabia Hussain, Martin E. Rottenberg, M. Islam
Publikováno v:
Scandinavian Journal of Immunology. 75:220-226
Improved tools are required to study immunopathogenesis of tuberculosis (TB). Mycobacterium tuberculosis antigen-stimulated T cell-based assays can detect TB but are less effective when responses are compromised such as in severe disease. We investig
Autor:
Sherin Zafar, Tom H. M. Ottenhoff, S. Brahmbhatt, Graham H. Bothamley, Rabia Hussain, Jan W. Drijfhout, F. V. Lopez, Hazel M. Dockrell, Ghaffar Dawood, Steven G. Smith
Publikováno v:
Clinical and Experimental Immunology. 128:140-148
SUMMARYIn order to identify T cell epitopes within the Mycobacterium leprae 45-kD serine-rich antigen, we analysed responses to overlapping 17-mer peptides encompassing the whole antigen in non-exposed UK controls, Pakistani leprosy patients and tube
Publikováno v:
Immunology. 96:620-627
Mycobacterium leprae-specific immunoglobulin G1 (IgG1) antibodies in patients with leprosy show a direct correlation with bacterial load (ρ=0·748; P < 0002) suggesting that IgG1 B-cell responses may be surrogate markers of disease progression. To i
Publikováno v:
Clinical and Experimental Immunology. 114:204-209
SUMMARYT cell responses play a critical role in determining protective responses to leprosy. Patients with self-limiting tuberculoid leprosy show high T cell reactivity, while patients with disseminated lepromatous form of the disease show absent to
Publikováno v:
Journal of clinical immunology. 31(5)
Dynamic cytokine profiles from endogenously activated T cells in transit from lymph node to the infected sites via the blood compartment after recent exposure to Mycobacterium tuberculosis may differentiate disease progressors from non-disease progre
Autor:
Bushra Jamil, Zahra Hasan, Javaid A Khan, S. Jamil, Maria Khan, Rabia Hussain, R. Ali, Muhammad Yusuf, Nosheen Nasir, Muhammad Irfan
Publikováno v:
Scandinavian journal of immunology. 69(3)
Protection against Mycobacterium tuberculosis infection is dependent on T cell and macrophage activation regulated by cytokines. Cytokines and chemokines produced at disease sites may be released into circulation. Data available on circulating cytoki
Publikováno v:
BMC Immunology, Vol 6, Iss 1, p 14 (2005)
BMC Immunology
BMC Immunology
Background Tuberculosis causes 3 million deaths annually. The most common site of tuberculosis is pulmonary however; extra-pulmonary forms of the disease also remain prevalent. Restriction of Mycobacterium tuberculosis depends on effective recruitmen
Publikováno v:
Immunology. 111(4)
Mycobacterium leprae (ML) GroES has been shown to induce strong T cell responses in tuberculoid as well as in exposed healthy contacts of leprosy patients, and therefore this antigen has been the focus of study as a potential vaccine candidate. Parad
Erythema nodosum leprosum (ENL) is a serious complication of lepromatous (L) disease in leprosy. We have previously shown that of the four IgG subclasses, IgG1 and IgG3 Mycobacterium leprae-specific antibodies are significantly lower in leprosy patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2644375fb953cdbded64296b2ffc83
https://europepmc.org/articles/PMC2200614/
https://europepmc.org/articles/PMC2200614/
Publikováno v:
Clinical and diagnostic laboratory immunology. 2(6)
Mycobacterium tuberculosis-specific antibodies (immunoglobulin M [IgM], IgE, IgG, and IgG subclasses) were determined in 164 tuberculosis patients (pulmonary involvement, n = 135; lymph node involvement, n = 29), 59 healthy household contacts (HC), a