Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shih Jie Chou"'
Autor:
Winnie Khor, Tzyh-Chang Hwang, Chih-Chien Wang, Aliaksandr A. Yarmishyn, Jiunn-Tyng Yeh, Shih-Hwa Chiou, Shih-Jie Chou
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102683- (2022)
Cystic fibrosis (CF) is a genetic disease affects CFTR channel synthesis. While 90 percent of the CF patients now benefit from small molecule target therapies, this treatment has yet to extend to those bearing nonsense mutations. Studies of these rar
Externí odkaz:
https://doaj.org/article/d320ba5238754044b926d5f68138bc5b
Autor:
Chian-Shiu Chien, Yueh Chien, Yi-Ying Lin, Ping-Hsing Tsai, Shih-Jie Chou, Aliaksandr A. Yarmishyn, Elham Rastegari, Ting-Xian Wang, Hsin-Bang Leu, Yi-Ping Yang, Mong-Lien Wang, Ying-Chun Jheng, Henkie Isahwan Ahmad Mulyadi Lai, Lo-Jei Ching, Teh-Ia Huo, Jong-Yuh Cherng, Chien-Ying Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Non-viral gene delivery holds promises for treating inherited diseases. However, the limited cloning capacity of plasmids may hinder the co-delivery of distinct genes to the transfected cells. Previously, the conjugation of maleimide-functionalized p
Externí odkaz:
https://doaj.org/article/06e7ba69acc949cfa46f67b06f9229a6
Autor:
Hao-Yu Tsai, Henkie Isahwan Ahmad Mulyadi Lai, Zhang-Yuan Chen, Tai-Chi Lin, Winnie Khor, Wen-Chuan Kuo, Jia-Pu Syu, Ping-Hsing Tsai, Yi-Ping Yang, Yueh Chien, Shih-Jen Chen, De-Kuang Hwang, Shih-Hwa Chiou, Shih-Jie Chou
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 159 (2022)
Autophagy plays a protective role in the retinal pigment epithelium (RPE) by eliminating damaged organelles in response to reactive oxygen species (ROS). Dual-specificity protein phosphatase 6 (DUSP6), which belongs to the DUSP subfamily, works as a
Externí odkaz:
https://doaj.org/article/3acef2f17b5d40a998d9455c9b402d5c
Autor:
Shih-Jie Chou, Yu-Ling Ko, Yu-Hsuan Yang, Aliaksandr A. Yarmishyn, Yu-Ting Wu, Chien-Tsun Chen, Hsin-Chen Lee, Yau-Huei Wei, Shih-Hwa Chiou
Publikováno v:
Stem Cell Research, Vol 30, Iss , Pp 201-205 (2018)
MERRF syndrome is predominantly caused by A8344G mutation in the mitochondrial DNA (mtDNA), affecting MT-TK gene, which impairs the mitochondrial electron transport chain function. Here, we report the generation of two isogenic induced pluripotent st
Externí odkaz:
https://doaj.org/article/78b2268b748b4d31afa77ca0a168bb31
Autor:
Hui-Yung Song, Yi-Ping Yang, Yueh Chien, Wei-Yi Lai, Yi-Ying Lin, Shih-Jie Chou, Mong-Lien Wang, Chien-Ying Wang, Hsin-Bang Leu, Wen-Chung Yu, Chian-Shiu Chien
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2381 (2021)
The late-onset type of Fabry disease (FD) with GLA IVS4 + 919G > A mutation has been shown to lead to cardiovascular dysfunctions. In order to eliminate variations in other aspects of the genetic background, we established the isogenic control of ind
Externí odkaz:
https://doaj.org/article/fa5d68840bc447008817fa477918d860
Autor:
Henkie Isahwan Ahmad Mulyadi Lai, Shih-Jie Chou, Yueh Chien, Ping-Hsing Tsai, Chian-Shiu Chien, Chih-Chien Hsu, Ying-Chun Jheng, Mong-Lien Wang, Shih-Hwa Chiou, Yu-Bai Chou, De-Kuang Hwang, Tai-Chi Lin, Shih-Jen Chen, Yi-Ping Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1320 (2021)
Angiotensin-converting enzyme 2 (ACE2) was identified as the main host cell receptor for the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its subsequent infection. In some coronavirus disease 2019 (COVID-19) patients, it
Externí odkaz:
https://doaj.org/article/dab18b80656047598413247a9e2e0e1b
Autor:
Yung-Fang Tu, Chian-Shiu Chien, Aliaksandr A. Yarmishyn, Yi-Ying Lin, Yung-Hung Luo, Yi-Tsung Lin, Wei-Yi Lai, De-Ming Yang, Shih-Jie Chou, Yi-Ping Yang, Mong-Lien Wang, Shih-Hwa Chiou
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2657 (2020)
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, affecting not only the healt
Externí odkaz:
https://doaj.org/article/e5f69ce23446439098ef0bc0a0364a1c
Autor:
Winnie Khor, Tzyh-Chang Hwang, Chih-Chien Wang, Aliaksandr A. Yarmishyn, Jiunn-Tyng Yeh, Shih-Hwa Chiou, Shih-Jie Chou
Publikováno v:
Stem Cell Research, Vol 60, Iss, Pp 102683-(2022)
Cystic fibrosis (CF) is a genetic disease affects CFTR channel synthesis. While 90 percent of the CF patients now benefit from small molecule target therapies, this treatment has yet to extend to those bearing nonsense mutations. Studies of these rar
Autor:
Yueh Chien, Shih-Jie Chou, Yuh-Lih Chang, Hsin-Bang Leu, Yi-Ping Yang, Ping-Hsing Tsai, Ying-Hsiu Lai, Kuan-Hsuan Chen, Wei-Chao Chang, Shih-Hsien Sung, Wen-Chung Yu
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1480 (2018)
(1) Background: A high incidence of intervening sequence (IVS)4+919 G>A mutation with later-onset cardiac phenotype have been reported in a majority of Taiwan Fabry cohorts. Some evidence indicated that conventional biomarkers failed to predict the l
Externí odkaz:
https://doaj.org/article/0d1c4dc170da436fa741dc6e8825aaac