Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Rik, P."'
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-5 (2024)
Abstract The family of secreted dimeric proteins known as the Transforming Growth Factor-β (TGF-β) family plays a critical role in facilitating intercellular communication within multicellular animals. A recent symposium on TGF-β Biology - Signali
Externí odkaz:
https://doaj.org/article/d0acd9558a5344b99d2a85d3e1ba8b9c
Publikováno v:
FEBS Open Bio, Vol 14, Iss 4, Pp 655-674 (2024)
Multifunctional enzyme, type‐1 (MFE1) catalyzes the second and third step of the β‐oxidation cycle, being, respectively, the 2E‐enoyl‐CoA hydratase (ECH) reaction (N‐terminal part, crotonase fold) and the NAD+‐dependent, 3S‐hydroxyacyl
Externí odkaz:
https://doaj.org/article/333c3c615e614729a5c9efb7d149d074
Autor:
Laura Dirkx, Sara I Van Acker, Yasmine Nicolaes, João Luís Reis Cunha, Rokaya Ahmad, Rik Hendrickx, Ben Caljon, Hideo Imamura, Didier G Ebo, Daniel C Jeffares, Yann G-J Sterckx, Louis Maes, Sarah Hendrickx, Guy Caljon
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012181 (2024)
Addressing the challenges of quiescence and post-treatment relapse is of utmost importance in the microbiology field. This study shows that Leishmania infantum and L. donovani parasites rapidly enter into quiescence after an estimated 2-3 divisions i
Externí odkaz:
https://doaj.org/article/c3328a026fb045d3b54dc41a434fc149
Autor:
Jérémie Zappia, Qiao Tong, Renée Van der Cruyssen, Frederique M. F. Cornelis, Cécile Lambert, Tiago Pinto Coelho, Juliane Grisart, Erika Kague, Rik J. Lories, Marc Muller, Dirk Elewaut, Chrissy L. Hammond, Christelle Sanchez, Yves Henrotin
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis (OA), and osteomodulin (OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However,
Externí odkaz:
https://doaj.org/article/ce5742b9c2b84d36af2ac8b2853ba263
Autor:
Nils Rother, Cansu Yanginlar, Geoffrey Prévot, Inge Jonkman, Maaike Jacobs, Mandy M.T. van Leent, Julia van Heck, Vasiliki Matzaraki, Anthony Azzun, Judit Morla-Folch, Anna Ranzenigo, William Wang, Roy van der Meel, Zahi A. Fayad, Niels P. Riksen, Luuk B. Hilbrands, Rik G.H. Lindeboom, Joost H.A. Martens, Michiel Vermeulen, Leo A.B. Joosten, Mihai G. Netea, Willem J.M. Mulder, Johan van der Vlag, Abraham J.P. Teunissen, Raphaël Duivenvoorden
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113458- (2023)
Summary: Innate immune memory, also called ''trained immunity,'' is a functional state of myeloid cells enabling enhanced immune responses. This phenomenon is important for host defense, but also plays a role in various immune-mediated conditions. We
Externí odkaz:
https://doaj.org/article/dff74b8c0faf4120b0eff5cf97c0a2a4
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5208 (2024)
Over the last decades, the survival of multiple myeloma (MM) patients has considerably improved. However, despite the availability of new treatments, most patients still relapse and become therapy-resistant at some point in the disease evolution. The
Externí odkaz:
https://doaj.org/article/9803360a86a44bb7b5adc0c223e40382
Autor:
Sumeet K. Tiwari, Boas C. L. van der Putten, Thilo M. Fuchs, Trung N. Vinh, Martin Bootsma, Rik Oldenkamp, Roberto La Ragione, Sebastien Matamoros, Ngo T. Hoa, Christian Berens, Joy Leng, Julio Álvarez, Marta Ferrandis-Vila, Jenny M. Ritchie, Angelika Fruth, Stefan Schwarz, Lucas Domínguez, María Ugarte-Ruiz, Astrid Bethe, Charlotte Huber, Vanessa Johanns, Ivonne Stamm, Lothar H. Wieler, Christa Ewers, Amanda Fivian-Hughes, Herbert Schmidt, Christian Menge, Torsten Semmler, Constance Schultsz
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Escherichia coli is an opportunistic pathogen which colonizes various host species. However, to what extent genetic lineages of E. coli are adapted or restricted to specific hosts and the genomic determinants of such adaptation or
Externí odkaz:
https://doaj.org/article/7a560aabe0c64a319f4f4d18e4ff943d
Autor:
Emmanuelle Charrin, Dina Dabaghie, Ilke Sen, David Unnersjö-Jess, Katja Möller-Hackbarth, Mikhail Burmakin, Rik Mencke, Sonia Zambrano, Jaakko Patrakka, Hannes Olauson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Transgenic overexpression of αKlotho in hepatocytes results in protection against renal insults, possibly through modulation of the ER stress response by circulating αKlotho. In contrast, αKlotho overexpressed in podocytes is not renoprotective.
Externí odkaz:
https://doaj.org/article/619b3e82d9e24b86ae6db800031da9d4
Autor:
Rik Paulus Bernardus Tonino, Mackenzie Tweardy, Stephan Wegerich, Rolf Brouwer, Jaap Jan Zwaginga, Martin Roelof Schipperus
Publikováno v:
Digital Biomarkers, Vol 6, Iss 3, Pp 117-126 (2022)
Introduction: Little is known if, and to what extent, outpatient red blood cell (RBC) transfusions benefit chronic transfusion-dependent patients. Costs, labour, and potential side effects of RBC transfusions cause a restrictive transfusion strategy
Externí odkaz:
https://doaj.org/article/cd259ba5dc134248a768e10cf7e91417
Publikováno v:
Ecology and Society, Vol 28, Iss 3, p 7 (2023)
Nigeria is a major rice-producing and rice-importing country in Africa, challenged with ensuring rice-food security for its growing population. Successive governments have implemented several strategies to increase local rice production such as rice
Externí odkaz:
https://doaj.org/article/c79444081e0a4ea8af28e3251682fe36