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Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2021, 37 (6-7), pp.632-638. ⟨10.1051/medsci/2021087⟩
médecine/sciences, 2021, 37 (6-7), pp.632-638. ⟨10.1051/medsci/2021087⟩
médecine/sciences, EDP Sciences, 2021, 37 (6-7), pp.632-638. ⟨10.1051/medsci/2021087⟩
médecine/sciences, 2021, 37 (6-7), pp.632-638. ⟨10.1051/medsci/2021087⟩
The cilium is a cell extension forming a distinct compartment of eukaryotic cell body with a complex and dynamic structure. This structure is highly conserved across species and ensures various functions as sensory and motility. In humans, ciliary dy
Autor:
Rajendra Prasad, Attilio Di Pietro, Shweta Nim, Stéphane Moreau, Elisabeth Thivet, Luisa Ronga, Marc Le Borgne, Solène Savrimoutou, Mathieu Marchivie, Jean Guillon
Publikováno v:
RSC Advances
RSC Advances, Royal Society of Chemistry, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, Royal Society of Chemistry, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
International audience; Two series of piperazinyl-pyrrolo[1,2-a]quinoxaline derivatives were prepared via a Buchwald–Hartwig cross-coupling reaction and then evaluated for their ability to inhibit the drug efflux activity of CaCdr1p and CaMdr1p tra
Autor:
Lisa Le Borgne, Charlotte Hendriks, Warren C. McNabb, Jane A. Mullaney, Nicole C. Roy, Alicia M. Barnett
Publikováno v:
American Journal of Physiology-Cell Physiology. 320:C794-C805
The development of alternative in vitro culture methods has increased in the last decade as three-dimensional organoids of various tissues, including those of the small and large intestines. Due to their multicellular composition, organoids offer adv
Autor:
Pierrick Le Borgne, Lise Bérard, Ndenga Tonduangu, Pascal Bilbault, Karine Alamé, François Lefebvre, Sepsis) (Clr), Stéphane Gennai, C.E. Lavoignet, Lauriane Cipolat, Yannick Gottwalles, Laure Abensur Vuillaume
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 1274, p 1274 (2021)
Journal of Personalized Medicine
Journal of Personalized Medicine, MDPI, 2021, 11 (12), pp.1274. ⟨10.3390/jpm11121274⟩
Journal of Personalized Medicine; Volume 11; Issue 12; Pages: 1274
Journal of Personalized Medicine
Journal of Personalized Medicine, MDPI, 2021, 11 (12), pp.1274. ⟨10.3390/jpm11121274⟩
Journal of Personalized Medicine; Volume 11; Issue 12; Pages: 1274
(1) Introduction: According to recent studies, the ratio of C-reactive-protein to lymphocyte is more sensitive and specific than other biomarkers associated to systemic inflammatory processes. This study aimed to determine the prognostic value of CLR
Autor:
Diogo Henrique Kita, Vivian Rotuno Moure, Malika Berredjem, Geraldo Picheth, Sabrina Lusvarghi, Ingrid Fatima Zattoni, Nathalie Guragossian, Fabiane Gomes de Moraes Rego, Suresh V. Ambudkar, Christelle Marminon, Marc Le Borgne, Glaucio Valdameri, Marcos Brown Gonçalves, Zouhair Bouaziz, Joachim Jose, Sofiane Bouacida, Billel Belhani, Thomas Moulenat
Publikováno v:
Scientific Reports
Scientific Reports, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR) in many cancers. The most promising strategy to overcome ABCG2-mediated MDR is the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c8cc9ea76f4d3466fc3592b560030c
https://hal.science/hal-03126318
https://hal.science/hal-03126318
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.66659⟩
eLife, Vol 10 (2021)
eLife, 2021, 10, ⟨10.7554/eLife.66659⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.66659⟩
eLife, Vol 10 (2021)
eLife, 2021, 10, ⟨10.7554/eLife.66659⟩
In multiple cell lineages, Delta-Notch signalling regulates cell fate decisions owing to unidirectional signalling between daughter cells. In Drosophila pupal sensory organ lineage, Notch regulates the intra-lineage pIIa/pIIb fate decision at cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c146b4395da6348ab038d128464d1d5
https://hal.archives-ouvertes.fr/hal-03368144/file/66659#downloads
https://hal.archives-ouvertes.fr/hal-03368144/file/66659#downloads
Autor:
Valerie Steier, Hélène Le-Borgne, Maryse Lowinski, Annick Parent, Magali Mathieu, David Papin, Florence Fassy, Laure Delarbre, Laurent Debussche, Rak Alexey, Jean-Pierre Marquette, Francis Duffieux, Jacques Houtmann, Bruno Genet, Cécile Delorme, Patrick Didier, Thomas Bertrand, Annabelle Lamberton
Publikováno v:
Small GTPases
KRAS genes belong to the most frequently mutated family of oncogenes in cancer. The G12C mutation, found in a third of lung, half of colorectal and pancreatic cancer cases, is believed to be responsible for a substantial number of cancer deaths. For
Autor:
Delphine Thibaut, Joy Lachat, Rémi Le Borgne, Allon Weiner, Jean-Marc Verbavatz, Alice Pascault
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.3781. ⟨10.1038/s41467-022-31237-z⟩
Nature Communications, 2022, 13 (1), pp.3781. ⟨10.1038/s41467-022-31237-z⟩
SummaryThe opportunistic fungal pathogen Candida albicans is normally commensal, residing in the mucosa of most healthy individuals. In susceptible hosts, its filamentous hyphal form can invade epithelial layers leading to superficial or severe syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce135123eaa99a9e9bce1bf06627766
https://doi.org/10.1101/2021.09.09.459426
https://doi.org/10.1101/2021.09.09.459426
Autor:
Catherine Durieu, Rémi Le Borgne, Fred Bernard, Julie Jouette, Sandra Claret, Antoine Guichet
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Frontiers media, 2021, 9, ⟨10.3389/fcell.2021.719582⟩
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Frontiers media, 2021, 9, ⟨10.3389/fcell.2021.719582⟩
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In cell biology, detection of protein subcellular localizations is often achieved by optical microscopy techniques and more rarely by electron microscopy (EM) despite the greater resolution offered by EM. One of the possible reasons was that protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f323311745161a6a8c62a4f04c632ce
https://hal.archives-ouvertes.fr/hal-03421207
https://hal.archives-ouvertes.fr/hal-03421207