Zobrazeno 71 - 80
of 114
pro vyhledávání: '"Ye Zheng"'
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 11, Iss 10, p e1004491 (2015)
PLoS Computational Biology, Vol 11, Iss 10, p e1004491 (2015)
Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells’ regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin immunopr
Autor:
Christina Chang, Jeniffer B. Hernandez, John Le Lay, Klaus H. Kaestner, Marc Montminy, Mathias Leblanc, Ye Zheng, David Grimm
Publikováno v:
Nature communications
Following their activation in response to inflammatory signals, innate immune cells secrete T cell polarizing cytokines that promote the differentiation of naïve CD4 T cells into T helper (Th) cell subsets. Amongst these, Th17 cells play a prominent
Publikováno v:
The Journal of Experimental Medicine
Signaling pathways involved in regulating T cell proliferation and survival are not well understood. Here we have investigated a possible role of the nuclear factor (NF)-kappaB pathway in regulating mature T cell function by using CD4+ T cells from p
Publikováno v:
Immunity. 16:257-270
Despite the established role of dendritic cells (DCs) in regulating T lymphocyte activation, intracellular mechanisms responsible for controlling DC function are largely undefined. Here, we have studied DCs from mice deficient in the p50, RelA, and c
Publikováno v:
Cell. 158(4)
SummaryThe homeostasis of multicellular organisms requires terminally differentiated cells to preserve their lineage specificity. However, it is unclear whether mechanisms exist to actively protect cell identity in response to environmental cues that
Autor:
David F. Carpio, Peter Bruzzo, Ruslan Medzhitov, Ming O. Li, Ye Zheng, Fateh Ouaaz, Veena M. Singh, Amer A. Beg
Publikováno v:
The Journal of Immunology. 166:7128-7135
Tissue damage induced by infection or injury can result in necrosis, a mode of cell death characterized by induction of an inflammatory response. In contrast, cells dying by apoptosis do not induce inflammation. However, the reasons for underlying di
Publikováno v:
Fertility and Sterility. 106:e270
Autor:
Fan Wang, Wen Zhang, Jianhua Li, Min Wu, Zhenghong Yuan, Peng Xiuhua, Jieliang Chen, Junyu Lin, Cuncun Chen, Ye Zheng
The hepatitis B virus (HBV) is a DNA virus that can cause chronic hepatitis B (CHB) in humans. Current therapies for CHB infection are limited in efficacy and do not target the pre-existing viral genomic DNA, which are present in the nucleus as a cov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b60473638492d473db13a0c812ed396
https://europepmc.org/articles/PMC3916035/
https://europepmc.org/articles/PMC3916035/
Publikováno v:
Cell Cycle. 13:3159-3160
The homeostasis of multicellular organisms requires terminally differentiated cells to preserve their lineage specificity. However, it is unclear if mechanisms exist to actively protect cell identity in response to environmental cues that confer func
Autor:
Yanling Feng, Ye Zheng, Di Tian, Yunwen Hu, Boyin Qin, Zhigang Song, Tao Yang, Yuqin Yang, Zhaoqin Zhu, Lixiang Chen, Xiaonan Zhang, Hua Yang, Bisheng Shi, Chunhua Xu, Wencai Guan, Fang Liu, Dong Zeng, Wenjiang Zhou, Xiaohui Zhou
Publikováno v:
Emerging Microbes & Infections
A new avian-origin influenza virus A (H7N9) recently crossed the species barrier and infected humans; therefore, there is an urgent need to establish mammalian animal models for studying the pathogenic mechanism of this strain and the immunological r