Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Winnie S Liang"'
Autor:
Kenneth Idler, Andreas Scherer, Charles Lu, Timothy K. McDaniel, Penelope Duerken-Hughes, K J. Langenbach, Seta Stanbouly, Charles Wang, Victoria Zismann, Keyur Talsania, Leming Shi, Margaret C. Cam, Shamoni Maheshwari, Zhipan Li, Luyao Ren, Petr Vojta, Mehdi Pirooznia, Jonathan J Keats, Rasika Kalamegham, Howard Jacob, Bao Tran, Liz Kerrigan, Baitang Ning, Ene Reimann, Jiri Drabek, Eric F. Donaldson, Zhaowei Yang, Sayed Mohammad Ebrahim Sahraeian, Daoud Meerzaman, Marc Sultan, Jessica Nordlund, Tsai-wei Shen, Sulev Kõks, Christopher E. Mason, Yunfei Guo, Winnie S. Liang, Claudia Catalanotti, Jeffrey M. Trent, Ying Yu, Roderick V. Jensen, Huixiao Hong, Malcolm Moos, Wenming Xiao, Stephen T. Sherry, Jonathan Foox, Joe Shuga, Hugo Y. K. Lam, Chunlin Xiao, Lijing Yao, Li Tai Fang, Wanqiu Chen, Marghoob Mohiyuddin, Monika Mehta, Rebecca Kusko, Roberta Maestro, Yongmei Zhao, Jonathan Adkins, Gary P. Schroth, Daniel Butler, Yuliya Kriga, Ogan D Abaan, Erich Jaeger, Yuanting Zheng, Daniela Gasparotto, Ulrika Liljedahl, Tiffany Hung, Eric Peters, Erica Tassone, Maryellen de Mars, Cu Nguyen, Lei Song, Bin Zhu, Weida Tong, Zivana Tezak, Justin B. Lack, Virginie Petitjean, Jyoti Shetty, Jing Li, Zhong Chen
Publikováno v:
Nat Biotechnol
The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms limits the implementation and uptake of cancer genomics. Here, we describe reference call sets o
Autor:
Stephen Pophal, Beate Peter, Winnie S. Liang, Nancy J. Scherer, Theresa A. Grebe, Colby Nielsen
Publikováno v:
American Journal of Medical Genetics Part A. 185:1532-1537
The 22q11.2 deletion syndrome (22q11.2 DS) is the most common deletion syndrome in humans. In most cases, it occurs de novo. A rare family of three with 22q11.2 deletion syndrome (22q11.2 DS) resulting from an unbalanced 18q;22q translocation is repo
Autor:
Amir Elyaderani, Gregory L. Powell, Nora I. Perrone-Bizzozero, Janet L. Neisewander, Michela Dell'Orco, Winnie S. Liang, Shobana Sekar, Annika Vannan
Publikováno v:
Biology
Volume 10
Issue 9
Biology, Vol 10, Iss 939, p 939 (2021)
Volume 10
Issue 9
Biology, Vol 10, Iss 939, p 939 (2021)
The RNA-binding protein HuD (a.k.a., ELAVL4) is involved in neuronal development and synaptic plasticity mechanisms, including addiction-related processes such as cocaine conditioned-place preference (CPP) and food reward. The most studied function o
Autor:
Rebecca F. Halperin, Apurva Hegde, Jessica D. Lang, Elizabeth A. Raupach, C4RCD Research Group, Christophe Legendre, Winnie S. Liang, Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman, Jeffrey M. Trent, Sampathkumar Rangasamy, Patrick Pirrotte, Nicholas J. Schork
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
The robust detection of disease-associated splice events from RNAseq data is challenging due to the potential confounding effect of gene expression levels and the often limited number of patients with relevant RNAseq data. Here we present a novel sta
Publikováno v:
Genome Research. 29:819-830
Oncoviral infection is responsible for 12%–15% of cancer in humans. Convergent evidence from epidemiology, pathology, and oncology suggests that new viral etiologies for cancers remain to be discovered. Oncoviral profiles can be obtained from cance
Autor:
Shobana Sekar, Winnie S. Liang
Publikováno v:
Non-coding RNA Research
Non-coding RNA Research, Vol 4, Iss 1, Pp 23-29 (2019)
Non-coding RNA Research, Vol 4, Iss 1, Pp 23-29 (2019)
Within the last decade, active research on circular RNAs (circRNAs) has dramatically improved our understanding of the expression and function of these non-coding RNAs. While several mechanisms for circRNA function have been proposed, including seque
Publikováno v:
Aging (Albany NY)
Alzheimer's disease (AD) is manifested by regional cerebral hypometabolism. Sirtuin 3 (Sirt3) is localized in mitochondria and regulates cellular metabolism, but the role of Sirt3 in AD-related hypometabolism remains elusive. We used expression profi
Autor:
Aleksandar Sekulic, Winnie S. Liang, Apurva M. Hegde, Nicholas J. Schork, Jeffrey A. Sosman, Rebecca F. Halperin, Patrick Pirrotte, Sampathkumar Rangasamy, Jeffrey M. Trent, Christophe Legendre, Elizabeth A. Raupach, Patricia LoRusso, Jessica D. Lang
Here we present a novel statistical approach to splicing outlier and differential splicing detection, implemented in a software package called Bisbee. We leverage Bisbee’s prediction of protein level effects to benchmark using matched RNAseq and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd320b75e67b290260608597c928805
https://doi.org/10.1101/2020.08.13.250167
https://doi.org/10.1101/2020.08.13.250167
Autor:
Fulvio D'Angelo, Mylan R. Blomquist, Francesca Pia Caruso, Joanna J. Phillips, Winnie S. Liang, John D. Carpten, Jeffrey M. Trent, Sara A. Byron, Rebecca F. Halperin, Michael D. Prados, Harshil Dhruv, Nhan L. Tran, Michele Ceccarelli, Sen Peng, Luciano Garofano, Michael E. Berens, Antonio Iavarone, David Craig, Shannon P. Fortin Ensign
Publikováno v:
Neuro-oncology advances, vol 2, iss 1
Neuro-oncology Advances
Neuro-oncology Advances
Background Tumor heterogeneity underlies resistance and disease progression in glioblastoma (GBM), and tumors most commonly recur adjacent to the surgical resection margins in contrast non-enhancing (NE) regions. To date, no targeted therapies have m
Autor:
Annalee Boyle, Geidy E. Serrano, Lori Cuyugan, Winnie S. Liang, Philipp Geiger, Thomas G. Beach, Shobana Sekar
Publikováno v:
Journal of visualized experiments : JoVE. (153)
Circular RNAs (circRNAs) are a class of non-coding RNAs involved in functions including micro-RNA (miRNA) regulation, mediation of protein-protein interactions, and regulation of parental gene transcription. In classical next generation RNA sequencin