Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tobias Pischon"'
Autor:
Vidya Velagapudi, Michael A. Schmidt, Rima Kaddurah-Daouk, Jennifer A. Kirwan, Tobias Pischon, Todd W. Mitchell
Publikováno v:
Clinical Chemistry. 65:827-832
Metabolomics and lipidomics play an important role in precision medicine. Global or targeted analyses of metabolites and lipids provide a specific metabolic phenotype, a “metabotype,” of an individual, which can provide important information on t
Autor:
Matthias B. Schulze, Clemens Wittenbecher, Annette Schürmann, Harald Grallert, Olga Kuxhaus, Andrea Teichmann, Karina Meidtner, Jennifer Kriebel, Heiner Boeing, Markus Jähnert, Meriem Ouni, Pascal Gottmann, Tobias Pischon
Publikováno v:
Diabetes 68, 188-197 (2019)
Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentr
Autor:
Jerzy Adamski, Susanne Jäger, Anna Floegel, Rafael R. C. Cuadrat, Matthias B. Schulze, Per Hoffmann, Clemens Wittenbecher, Cornelia Prehn, Tobias Pischon
Publikováno v:
Nutrients 12:3890 (2020)
Nutrients, Vol 12, Iss 3890, p 3890 (2020)
Nutrients
Volume 12
Issue 12
Nutrients, 12(12):3890
Nutrients, Vol 12, Iss 3890, p 3890 (2020)
Nutrients
Volume 12
Issue 12
Nutrients, 12(12):3890
Circulating levels of branched-chain amino acids, glycine, or aromatic amino acids have been associated with risk of type 2 diabetes. However, whether those associations reflect causal relationships or are rather driven by early processes of disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6cadd172b6360ca022249ee773f456
http://edoc.mdc-berlin.de/19788/7/19788suppl.zip
http://edoc.mdc-berlin.de/19788/7/19788suppl.zip
Autor:
Francesco Capozzi, Jildau Bouwman, Damariz Rivero, Alessandra Bordoni, G. De Tré, B. De Baets, Francesco Taglino, Katharina Nimptsch, Alessia Trimigno, N. De Cock, Tobias Pischon, Carl Lachat, Fulvio Mattivi, Mariona Pinart, Giovanni Felici, Duccio Cavalieri, Pietro Franceschi, Rosario Lombardo, Franco Miglietta, Francesco Vitali
Publikováno v:
Genes & Nutrition
Genes & nutrition 13 (2018). doi:10.1186/s12263-018-0601-y
info:cnr-pdr/source/autori:Vitali F.; Lombardo R.; Rivero D.; Mattivi F.; Franceschi P.; Bordoni A.; Trimigno A.; Capozzi F.; Felici G.; Taglino F.; Miglietta F.; De Cock N.; Lachat C.; De Baets B.; De Tre G.; Pinart M.; Nimptsch K.; Pischon T.; Bouwman J.; Cavalieri D./titolo:ONS: An ontology for a standardized description of interventions and observational studies in nutrition/doi:10.1186%2Fs12263-018-0601-y/rivista:Genes & nutrition/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:13
GENES AND NUTRITION
Genes & Nutrition, Vol 13, Iss 1, Pp 1-9 (2018)
Genes and Nutrition, 1, 13
Genes & nutrition 13 (2018). doi:10.1186/s12263-018-0601-y
info:cnr-pdr/source/autori:Vitali F.; Lombardo R.; Rivero D.; Mattivi F.; Franceschi P.; Bordoni A.; Trimigno A.; Capozzi F.; Felici G.; Taglino F.; Miglietta F.; De Cock N.; Lachat C.; De Baets B.; De Tre G.; Pinart M.; Nimptsch K.; Pischon T.; Bouwman J.; Cavalieri D./titolo:ONS: An ontology for a standardized description of interventions and observational studies in nutrition/doi:10.1186%2Fs12263-018-0601-y/rivista:Genes & nutrition/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:13
GENES AND NUTRITION
Genes & Nutrition, Vol 13, Iss 1, Pp 1-9 (2018)
Genes and Nutrition, 1, 13
Background The multidisciplinary nature of nutrition research is one of its main strengths. At the same time, however, it presents a major obstacle to integrate data analysis, especially for the terminological and semantic interpretations that specif
Publikováno v:
American Journal of Epidemiology. 183:553-560
Higher levels of insulin-like growth factor-binding protein 3 (IGFBP-3) might raise the risk of type 2 diabetes mellitus (T2DM) via binding of insulin-like growth factor 1 (IGF-1), an insulin-like hormone that is involved in glucose homeostasis. We i
Autor:
Rosario Lombardo, Luis Castaño, Janette Walton, Michèle Guillaume, Katharina Nimptsch, Jean Tafforeau, Christophe Matthys, Antonietta Robino, Heiner Boeing, Christina Kleiser, Marie Standl, Eha Nurk, Thorsten Heuer, Ute Nöthlings, Mariona Pinart, Chen Yang, Maria De Angelis, Paolo Gasparini, Jakob Linseisen, Marco Gobbetti, Jordi Merino, Jildau Bouwman, Luis Masana, Birgit Christiane Zyriax, Lars O. Dragsted, Nathalie De Cock, Tobias Pischon, Anne-Françoise Donneau, Raffaella Canali, Holger Schulz, Eberhard Windler, Elena Biagi, Eamon Laird, Giuditta Perozzi, Marta Stelmach-Mardas, Stephanie Jeran, Massimo D'Archivio, Gemma Rojo-Martínez, Carl Lachat, Janett Barbaresko
Publikováno v:
Pinart, M, Nimptsch, K, Bouwman, J, Dragsted, L O, Yang, C, De Cock, N, Lachat, C, Perozzi, G, Canali, R, Lombardo, R, D'Archivio, M, Guillaume, M, Donneau, A-F, Jeran, S, Linseisen, J, Kleiser, C, Nöthlings, U, Barbaresko, J, Boeing, H, Stelmach-Mardas, M, Heuer, T, Laird, E, Walton, J, Gasparini, P, Robino, A, Castaño, L, Rojo-Martínez, G, Merino, J, Masana, L, Standl, M, Schulz, H, Biagi, E, Nurk, E, Matthys, C, Gobbetti, M, de Angelis, M, Windler, E, Zyriax, B-C, Tafforeau, J & Pischon, T 2018, ' Joint data analysis in nutritional epidemiology : Identification of observational studies and minimal requirements ', Journal of Nutrition, vol. 148, no. 2, pp. 285-297 . https://doi.org/10.1093/jn/nxx037
JOURNAL OF NUTRITION
Journal of Nutrition, 2, 148, 285-297
JOURNAL OF NUTRITION
Journal of Nutrition, 2, 148, 285-297
BACKGROUND: Joint data analysis from multiple nutrition studies may improve the ability to answer complex questions regarding the role of nutritional status and diet in health and disease. OBJECTIVE: The objective was to identify nutritional observat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00bb688c812ef8f8bf67737446b639c
https://curis.ku.dk/portal/da/publications/joint-data-analysis-in-nutritional-epidemiology(66cff4d5-8a32-4802-a4e1-b5cc93cd6dd5).html
https://curis.ku.dk/portal/da/publications/joint-data-analysis-in-nutritional-epidemiology(66cff4d5-8a32-4802-a4e1-b5cc93cd6dd5).html
Autor:
Diana van Heemst, Matthias B. Schulze, Joris Deelen, Jerzy Adamski, Ramneek Gupta, Sophie Molnos, P. Eline Slagboom, Valborg Gudmundsdottir, Simone Wahl, Annette Peters, Ewan R. Pearson, Anette-G. Ziegler, Anna Floegel, Harald Grallert, E. Marelise W. Eekhoff, A.M.C. Simonis-Bik, Christian Herder, Helle Krogh Pedersen, René Pool, Eco J. C. de Geus, Mark Haid, Gonneke Willemsen, Nienke van Leeuwen, Dorret I. Boomsma, Karsten Suhre, Michael Roden, Tobias Pischon, Daniela Much, Leen M 't Hart, Christian Gieger, Marian Beekman, Wolfgang Rathmann, Mark H. H. Kramer, Cornelia Prehn, Anna Jonsson, Wolfgang Bernigau, Harmen H.M. Draisma, Sandra Hummel, Barbara Thorand, Mark I. McCarthy, Michaela Breier, Heiner Boeing, Rui Wang-Sattler, Søren Brunak
Publikováno v:
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia, 61(1), 117-129. Springer Verlag
Diabetologia, 61(1), 117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A E, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 'T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study ', Diabetologia, vol. 61, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2017, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia
Diabetologia, 61(1):117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & ’T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia, 61(1), 117-129. Springer Verlag
Diabetologia, 61(1), 117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A E, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 'T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study ', Diabetologia, vol. 61, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2017, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia
Diabetologia, 61(1):117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & ’T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Aims/hypothesis Circulating metabolites have been shown to reflect metabolic changes during the development of type 2 diabetes. In this study we examined the association of metabolite levels and pairwise metabolite ratios with insulin responses after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3138b1b57ae911b25528c3590b8b87bd
https://doi.org/10.1007/s00125-017-4436-7
https://doi.org/10.1007/s00125-017-4436-7
Autor:
Jildau Bouwman, Niels Hulstaert, Eamon Laird, John Van Camp, Giuditta Perozzi, Marta Stelmach-Mardas, Patrick Kolsteren, Axelle Hoge, Stéphanie Maria Palombi, Maria De Angelis, Chen Yang, Irina Dobre, Hendrik De Ruyck, Carl Lachat, Rosario Lombardo, Guy De Tré, Christophe Matthys, Katharina Nimptsch, Peter Clarys, Angela A. Rivellese, Dolores Corella, Raffaella Canali, Marco Gobbetti, Jean Tafforeau, Fabio Minervini, Tobias Pischon, Sofian De Clercq, Laura Kehoe, Antoon Bronselaer, Mariona Pinart, Lars O. Dragsted, Bernard De Baets, Janette Walton, Nathalie De Cock, Rosalba Giacco, Oscar Coltell
Publikováno v:
Yang, C, Pinart, M, Kolsteren, P, Van Camp, J, De Cock, N, Nimptsch, K, Pischon, T, Laird, E, Perozzi, G, Canali, R, Hoge, A, Stelmach-Mardas, M, Dragsted, L O, Palombi, S M, Dobre, I, Bouwman, J, Clarys, P, Minervini, F, De Angelis, M, Gobbetti, M, Tafforeau, J, Coltell, O, Corella, D, De Ruyck, H, Walton, J, Kehoe, L, Matthys, C, De Baets, B, De Tré, G, Bronselaer, A, Rivellese, A, Giacco, R, Lombardo, R, De Clercq, S, Hulstaert, N & Lachat, C 2017, ' Perspective : Essential study quality descriptors for data from nutritional epidemiologic research ', Advances in Nutrition, vol. 8, no. 5, pp. 639-651 . https://doi.org/10.3945/an.117.015651
Advances in nutrition (Bethesda Md., Print) 8 (2017): 639–651. doi:10.3945/an.117.015651
info:cnr-pdr/source/autori:Yang, Chen; Pinart, Mariona; Kolsteren, Patrick; Van Camp, John; De Cock, Nathalie; Nimptsch, Katharina; Pischon, Tobias; Laird, Eamon; Perozzi, Giuditta; Canali, Raffaella; Hoge, Axelle; Stelmach-Mardas, Marta; Dragsted, Lars Ove; Palombi, Stephanie Maria; Dobre, Irina; Bouwman, Jildau; Clarys, Peter; Minervini, Fabio; De Angelis, Maria; Gobbetti, Marco; Tafforeau, Jean; Coltell, Oscar; Corella, Dolores; De Ruyck, Hendrik; Walton, Janette; Kehoe, Laura; Matthys, Christophe; De Baets, Bernard; De Tre, Guy; Bronselaer, Antoon; Rivellese, Angela; Giacco, Rosalba; Lombardo, Rosario; De Clercq, Sofian; Hulstaert, Niels; Lachat, Carl/titolo:Perspective: Essential Study Quality Descriptors for Data from Nutritional Epidemiologic Research/doi:10.3945%2Fan.117.015651/rivista:Advances in nutrition (Bethesda Md., Print)/anno:2017/pagina_da:639/pagina_a:651/intervallo_pagine:639–651/volume:8
Advances in Nutrition, 5, 8, 639-651
Advances in Nutrition
Advances in nutrition (Bethesda Md., Print) 8 (2017): 639–651. doi:10.3945/an.117.015651
info:cnr-pdr/source/autori:Yang, Chen; Pinart, Mariona; Kolsteren, Patrick; Van Camp, John; De Cock, Nathalie; Nimptsch, Katharina; Pischon, Tobias; Laird, Eamon; Perozzi, Giuditta; Canali, Raffaella; Hoge, Axelle; Stelmach-Mardas, Marta; Dragsted, Lars Ove; Palombi, Stephanie Maria; Dobre, Irina; Bouwman, Jildau; Clarys, Peter; Minervini, Fabio; De Angelis, Maria; Gobbetti, Marco; Tafforeau, Jean; Coltell, Oscar; Corella, Dolores; De Ruyck, Hendrik; Walton, Janette; Kehoe, Laura; Matthys, Christophe; De Baets, Bernard; De Tre, Guy; Bronselaer, Antoon; Rivellese, Angela; Giacco, Rosalba; Lombardo, Rosario; De Clercq, Sofian; Hulstaert, Niels; Lachat, Carl/titolo:Perspective: Essential Study Quality Descriptors for Data from Nutritional Epidemiologic Research/doi:10.3945%2Fan.117.015651/rivista:Advances in nutrition (Bethesda Md., Print)/anno:2017/pagina_da:639/pagina_a:651/intervallo_pagine:639–651/volume:8
Advances in Nutrition, 5, 8, 639-651
Advances in Nutrition
Pooled analysis of secondary data increases the power of research and enables scientific discovery in nutritional epidemiology. Information on study characteristics that determine data quality is needed to enable correct reuse and interpretation of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c310d680bdf722be4d7ce7cc5b6e86
http://edoc.mdc-berlin.de/16766/7/16766suppl.docx
http://edoc.mdc-berlin.de/16766/7/16766suppl.docx
Autor:
Janine Kröger, Konstantin Strauch, Martina Müller-Nurasyid, Karina Meidtner, Heiner Boeing, Matthias B. Schulze, Christian Gieger, Cornelia Prehn, Sapna Sharma, Jerzy Adamski, Susanne Jäger, Anna Floegel, Harald Grallert, Simone Wahl, Annette Peters, Melanie Waldenberger, Per Hoffmann, Karsten Suhre, Tobias Pischon
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Sci. Rep. 7:6037 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Sci. Rep. 7:6037 (2017)
Diabetes-associated metabolites may aid the identification of new risk variants for type 2 diabetes. Using targeted metabolomics within a subsample of the German EPIC-Potsdam study (n = 2500), we tested previously published SNPs for their association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07609678ba12ec50d658df27f1dbda93
http://edoc.mdc-berlin.de/16679/2/16679suppl.pdf
http://edoc.mdc-berlin.de/16679/2/16679suppl.pdf
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178504 (2017)
PLoS ONE
PLoS ONE
In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these chall