Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Timo K. van den Berg"'
Autor:
Robin van Bruggen, Anton T.J. Tool, Xi Wen Zhao, Taco W. Kuijpers, Nezihe Köker, Michel van Houdt, Mustafa Yavuz Köker, Paul Verkuijlen, Timo K. van den Berg, Panagiota Bouti, Hanke L. Matlung, Sinan Akbayram, Ozlem Keskin
Publikováno v:
Cancer immunology research, 9(2), 147-155. American Association for Cancer Research Inc.
The CD47–signal regulatory protein-alpha (SIRPα) immune checkpoint constitutes a therapeutic target in cancer, and initial clinical studies using inhibitors of CD47–SIRPα interactions in combination with tumor-targeting antibodies show promisin
Autor:
A. Robin Temming, Matthias Tammes Buirs, Arthur E. H. Bentlage, Louise W. Treffers, Hannah Feringa, Steven W. de Taeye, Taco W. Kuijpers, Sietse Q. Nagelkerke, Giso Brasser, Juk Yee Mok, Wim J. E. van Esch, Timo K. van den Berg, Theo Rispens, C. Ellen van der Schoot, Gestur Vidarsson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in immunology, 12:594773. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in immunology, 12:594773. Frontiers Media S.A.
Antibody-mediated blood disorders ensue after auto- or alloimmunization against blood cell antigens, resulting in cytopenia. Although the mechanisms of cell destruction are the same as in immunotherapies targeting tumor cells, many factors are still
Autor:
Sander Engels, Katka Franke, Timo K. van den Berg, Anja J. de Jong, Muhammet F. Gulen, Monika C. Wolkers, Edith M. Janssen, Andrea Ablasser, Melania Balzarolo, Bas van Steensel
Publikováno v:
Open Biology, Vol 11, Iss 3 (2021)
Open biology, 11(3):210030. Royal Society Publishing
Open Biology
Open biology, 11(3):210030. Royal Society Publishing
Open Biology
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition of microbial infections. Microbial DNA is frequently methylated at the N 6 position of adenines (m6A), a modification that is rare in mammalian host DNA. We
Autor:
Pieter F. van der Meer, Petros Papadopoulos, Dirk de Korte, Laura Gutierrez, María Villa-Fajardo, Vishal Salunkhe, Timo K. van den Berg, Brunette B. Daal, Iris M. De Cuyper
Publikováno v:
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Platelets, 30(3), 368-379. Informa Healthcare
instname
Platelets, 30(3), 368-379. Informa Healthcare
Platelet concentrates (PCs) represent a blood transfusion product with a major concern for safety as their storage temperature (20-24°C) allows bacterial growth, and their maximum storage time period (less than a week) precludes complete microbiolog
Autor:
Hung-Jen Chen, Anton Tj Tool, Marieke C.S. Boshuizen, Marion J.J. Gijbels, Esther Lutgens, Jan Van den Bossche, Annette E. Neele, Marten A. Hoeksema, Saskia van der Velden, Menno P.J. de Winther, Timo K. van den Berg, Hanke L. Matlung
Publikováno v:
Frontiers in Immunology, 11:594603. Frontiers Media S.A.
Neele, A E, Chen, H J, Gijbels, M J J, van der Velden, S, Hoeksema, M A, Boshuizen, M C S, Van den Bossche, J, Tool, A T, Matlung, H L, van den Berg, T K, Lutgens, E & de Winther, M P J 2021, ' Myeloid Ezh2 Deficiency Limits Atherosclerosis Development ', Frontiers in Immunology, vol. 11, 594603 . https://doi.org/10.3389/fimmu.2020.594603
Frontiers in immunology, 11:594603. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Neele, A E, Chen, H J, Gijbels, M J J, van der Velden, S, Hoeksema, M A, Boshuizen, M C S, Van den Bossche, J, Tool, A T, Matlung, H L, van den Berg, T K, Lutgens, E & de Winther, M P J 2021, ' Myeloid Ezh2 Deficiency Limits Atherosclerosis Development ', Frontiers in Immunology, vol. 11, 594603 . https://doi.org/10.3389/fimmu.2020.594603
Frontiers in immunology, 11:594603. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Macrophages define a key component of immune cells present in atherosclerotic lesions and are central regulators of the disease. Since epigenetic processes are important in controlling macrophage function, interfering with epigenetic pathways in macr
Autor:
Arno van Heijst, Judy Geissler, Emile van den Akker, Michel van Houdt, Wouter Koole, Koen J. van Aerde, Han J.M.P. Verhagen, Ivo van der Bijl, Cathelijn E.M. Aarts, Gerald Jaspers, Christine W. Bruggeman, Anton T.J. Tool, Evelien G. G. Sprenkeler, Thatjana Gardeitchik, Floris P. J. van Alphen, Iris C. Kreft, Martin de Boer, Hans Janssen, Taco W. Kuijpers, Stefanie S. V. Henriet, Kian D. Liem, Paul Verkuijlen, Timo K. van den Berg, Simon Tol, Robin van Bruggen
Publikováno v:
Blood, 135(24), 2171-2181. American Society of Hematology
Blood, 135, 24, pp. 2171-2181
Blood, 135, 2171-2181
Blood
Blood, 135, 24, pp. 2171-2181
Blood, 135, 2171-2181
Blood
Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics, by coactivating serum response factor. Recently, the first human with MKL1 deficiency, leading to a novel primary immunodef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b809e6d92354a647f689ade8ce4f44
https://pure.amc.nl/en/publications/mkl1-deficiency-results-in-a-severe-neutrophil-motility-defect-due-to-impaired-actin-polymerization(8e622be7-3e65-412f-b3c2-5eedcabc6963).html
https://pure.amc.nl/en/publications/mkl1-deficiency-results-in-a-severe-neutrophil-motility-defect-due-to-impaired-actin-polymerization(8e622be7-3e65-412f-b3c2-5eedcabc6963).html
Autor:
Vishal Salunkhe, Sjaak Philipsen, Rutger W W Brouwer, Timo K. van den Berg, Nynke Gillemans, Jeroen Demmers, Lianne van de Laar, Erikjan Rijkers, Wilfred F. J. van IJcken, Noemí Caballero-Sánchez, Iris M. De Cuyper, Pieter De Bleser, Maaike R. Scheenstra, Laura Gutierrez, Andrea Acebes-Huerta, Patricia Martínez-Botía, Benjamin Nota, Andrea M. Woltman, Taco W. Kuijpers
Publikováno v:
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Journal of leukocyte biology, 110(4), 735-751. FASEB
Journal of Leukocyte Biology, 1-17. John Wiley & Sons Inc.
STARTPAGE=1;ENDPAGE=17;ISSN=0741-5400;TITLE=Journal of Leukocyte Biology
instname
Journal of leukocyte biology, 110(4), 735-751. FASEB
Journal of Leukocyte Biology, 1-17. John Wiley & Sons Inc.
STARTPAGE=1;ENDPAGE=17;ISSN=0741-5400;TITLE=Journal of Leukocyte Biology
Dendritic cells (DCs) are key immune modulators and are able to mount immune responses or tolerance. DC differentiation and activation imply a plethora of molecular and cellular responses, including transcriptional changes. PU.1 is a highly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948526b0e9c69ecf828402662f0b66b5
http://hdl.handle.net/10651/57182
http://hdl.handle.net/10651/57182
Autor:
Katka Franke, Saravanan Y. Pillai, Mark Hoogenboezem, Marion J. J. Gijbels, Hanke L. Matlung, Judy Geissler, Hugo Olsman, Chantal Pottgens, Patrick J. van Gorp, Maria Ozsvar-Kozma, Yasuyuki Saito, Takashi Matozaki, Taco W. Kuijpers, Rudi W. Hendriks, Georg Kraal, Christoph J. Binder, Menno P. J. de Winther, Timo K. van den Berg
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:570963. Frontiers Media S.A.
The inhibitory immunoreceptor SIRP alpha is expressed on myeloid and neuronal cells and interacts with the broadly expressed CD47. CD47-SIRP alpha interactions form an innate immune checkpoint and its targeting has shown promising results in cancer p
Autor:
Timo K. van den Berg, Sanne M. Meinderts, Robin van Bruggen, Judy Geissler, Sadaf Pakdaman, Michael W.T. Tanck, Taco W. Kuijpers, J.L. Kerkhoffs, Christine W. Bruggeman, Karin Fijnvandraat, Anita W. Rijneveld, Bart J. Biemond, Anoosha Habibi, Joep W. R. Sins, Sietse Q. Nagelkerke
Publikováno v:
Meinderts, S M, Sins, J W R, Fijnvandraat, K, Nagelkerke, S Q, Geissler, J, Tanck, M W, Bruggeman, C, Biemond, B J, Rijneveld, A W, Kerkhoffs, J L H, Pakdaman, S, Habibi, A, Van Bruggen, R, Kuijpers, T W, Pirenne, F & Van Den Berg, T K 2017, ' Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease ', Blood, vol. 130, no. 19, pp. 2121-2130 . https://doi.org/10.1182/blood-2017-05-784876
Blood, 130(19), 2121-2130. American Society of Hematology
Blood, 130(19), 2121-2130. American Society of Hematology
Red blood cell (RBC) transfusions are of vital importance in patients with sickle cell disease (SCD). However, a major complication of transfusion therapy is alloimmunization. The low-affinity Fcg receptors, expressed on immune cells, are important r
Autor:
Martin de Boer, Floris P. J. van Alphen, Martijn van der Kuip, Taco W. Kuijpers, Hans Janssen, Suzanne W.J. Terheggen, Karin van Leeuwen, Timo K. van den Berg, Judy Geissler, Alexander B. Meijer, Dirk Roos, Esther de Vries
Publikováno v:
Human Mutation. 38:1402-1411
Hermansky-Pudlak syndrome type 2 (HPS2) is a syndrome caused by mutations in the beta-3A subunit of the adaptor protein (AP)-3 complex (AP3B1 gene). We describe five unreported cases with four novel mutations, one of which caused aberrant pre-mRNA sp