Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Teng-Teng Chung"'
Autor:
Gerard Ruiz-Babot, Alessandra Mancini, Demetris Mariannis, Teng-Teng Chung, Tarek Ezzat Abdel-Aziz, Leonardo Guasti, Peter J. King, Fausto Palazzo, Irene Hadjidemetriou, Katja Kiseljak-Vassiliades, Margaret E. Wierman, William Drake, Aimee diMarco, Laila Parvanta, James Pittaway, Celso E. Gomez-Sanchez, Katia Mariniello
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 193
The adrenal cortex governs fundamental metabolic processes though synthesis of glucocorticoid, miner-alocorticoids and androgens. Studies in rodents have demonstrated that the cortex undergoes a self-renewal process and that capsular/subcapsular stem
Publikováno v:
Endocrinology
Bioluminescence resonance energy transfer analysis is used to study the interaction between melanocortin 2 receptor (MC2R) accessory protein and the MC2R and provides evidence for protein kinase A-dependent conformational changes in the receptor comp
Publikováno v:
European Journal of Endocrinology
ContextFamilial glucocorticoid deficiency (FGD) is a rare autosomal recessive disease, characterised by isolated glucocorticoid deficiency in the absence of mineralocorticoid deficiency. Inactivating mutations in the ACTH receptor (melanocortin-2-rec
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 23:159-165
Familial glucocorticoid deficiency is an autosomal recessive disorder resulting from defects in the action of adrenocorticotropic hormone (ACTH) to stimulate glucocorticoid synthesis in the adrenal. Production of mineralocorticoids by the adrenal is
Autor:
Adrian J. L. Clark, Peter J. King, Li F. Chan, Louise A. Metherell, Tom R. Webb, J. P. Chapple, Sadani N. Cooray, Teng-Teng Chung
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 93:4948-4954
Context: There are at least 24 missense, nonconservative mutations found in the ACTH receptor [melanocortin 2 receptor (MC2R)] that have been associated with the autosomal recessive disease familial glucocorticoid deficiency (FGD) type 1. The charact
Publikováno v:
Clinical endocrinology. 84(4)
BACKGROUND Patients taking hydrocortisone (HC) replacement for primary or secondary adrenal failure require individual adjustment of their dose. In addition to modifying the administered doses of HC for each patient, physicians are increasingly inter
Publikováno v:
Endocrine Abstracts.
Autor:
Eirini Meimaridou, Leonardo Guasti, Teng-Teng Chung, Li F. Chan, J. Paul Chapple, Michael E. Cheetham, Tom R. Webb, Michaela Egertová, Adrian J. L. Clark, Louise A. Metherell, Maurice R. Elphick, Sadani N. Cooray
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(15)
The melanocortin receptor (MCR) family consists of 5 G protein-coupled receptors (MC1R–MC5R) with diverse physiologic roles. MC2R is a critical component of the hypothalamic–pituitary–adrenal axis, whereas MC3R and MC4R have an essential role i