Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shreerang Bhide"'
Autor:
Lisa Pickering, Richard Stone, Ian Chau, James I. MacRae, Karla Lingard, Susana Banerjee, Barry Ward, Jessica Bazin, William Gordon, Naureen Starling, Katalin A. Wilkinson, Mary O'Brien, Anna Robinson, Joanne Droney, Sacheen Kumar, Emma Nicholson, Martin Pule, Isla Leslie, Andreas M. Schmitt, Ambrosius P. Snijders, Karolina Rzeniewicz, Emma Nye, Benjamin Shum, Mary Mangwende, Scott Shepherd, Nalinie Joharatnam-Hogan, Robyn L. Shea, Michael Howell, Anthony J. Swerdlow, Shaman Jhanji, Simon Caidan, Eleanor Carlyle, Laura Amanda Boos, Annika Fendler, Kevin W. Ng, Kate Tatham, Leila Mekkaoui, Tim Slattery, Margaret Crawford, Firza Gronthoud, Philip Hobson, Camila Gomes, Robert J. Wilkinson, Jerome Nicod, Charles Swanton, Mike Gavrielides, Kim Edmonds, Robin L. Jones, Fiona Byrne, Laura Cubitt, Alison Reid, Lucy Holt, Ana Agua-Doce, Ruth Harvey, Sarah Sarker, Spyridon Gennatas, Camille L. Gerard, Andrew Furness, Hamid Ahmod, Liam Welsh, Nicholas van As, Olivia Curtis, Nadia Yousaf, Mary Wu, Nicholas C. Turner, Christina Messiou, David Cunningham, Zayd Tippu, Georgina H. Cornish, Sonia Gandhi, Helen R. Flynn, Harshil Patel, Yasir Khan, James Larkin, Lewis Au, George Kassiotis, Samra Turajlic, Maddalena Cerrone, Clemency Stephenson, Steve Gamblin, Kate Young, Wenyi Xie, Shreerang Bhide, Robert L. Goldstone, Alicia Okines, Kevin J. Harrington, Lyra Del Rosario
Publikováno v:
Nature Cancer
Research Square
article-version (status) pre
article-version (number) 1
Research Square
article-version (status) pre
article-version (number) 1
Patients with cancer have higher COVID-19 morbidity and mortality. Here we present the prospective CAPTURE study, integrating longitudinal immune profiling with clinical annotation. Of 357 patients with cancer, 118 were SARS-CoV-2 positive, 94 were s
Autor:
Lisa Pickering, Nalinie Joharatnam-Hogan, Fiona Kinnaird, Andrew Furness, Mary Wu, Daqi Deng, Sina Namjou, Sarah Sarker, Aljosja Rogiers, Aida Murra, Justine Korteweg, Nicholas van As, Nicholas C. Turner, Anna Robinson, Joanne Droney, Kema Peat, Shaman Jhanji, Mike Gavrielides, Isla Leslie, Lauren Dowdie, Tara Foley, Christina Messiou, Natalie Ash, Taja Barber, Andrea Emslie-Henry, Simon Caidan, Karolina Rzeniewicz, Katalin A. Wilkinson, Ruth Harvey, Annika Fendler, Kate Tatham, Andreas M. Schmitt, Sunil Iyengar, Shreerang Bhide, Kayleigh Kelly, David L.V. Bauer, Benjamin Shum, Kim Edmonds, Gail Gardner, Scott Shepherd, Mark Ethell, Laura Amanda Boos, Liam Welsh, Robert J. Wilkinson, Lucy Holt, Alicia Okines, William Gordon, James I. MacRae, Maddalena Cerrone, Kevin J. Harrington, Mary Mangwende, Hamid Ahmod, Olivia Curtis, Emma Nicholson, Darren Murray, Susana Banerjee, Firza Gronthoud, Bhavna Oza, Naureen Starling, Wenyi Xie, Alison Reid, Karla Lingard, Ana Agua-Doce, Charles Swanton, Sacheen Kumar, Lewis Au, Michael Howell, James Larkin, Camille L. Gerard, Emma C Wall, Jessica Bazin, Ian Chau, Robin L. Jones, Fiona Byrne, Robyn L. Shea, Denise Kelly, Nadia Yousaf, Steve Gamblin, Kate Young, Sonia Gandhi, Susanna Walker, Eleanor Carlyle, Javier Pascual, David Cunningham, Samra Turajlic, Clemency Stephenson, Zayd Tippu, Gavin Kelly, Mary O'Brien, Sheima Farag, Molly O’Flaherty, George Kassiotis, Wanyuan Cui, Justin Mencel, Lyra Del Rosario, Simon Rodney
Publikováno v:
Nature cancer
Nature Cancer
Nature Cancer
Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune monitoring (CAPTURE) (NCT03226886) is a prospective cohort study of COVID-19 immunity in patients with cancer. Here we evaluated 585 patients following administration of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90b7e7f14703f40105aa2f1e5740b1a
https://doi.org/10.21203/rs.3.rs-916303/v1
https://doi.org/10.21203/rs.3.rs-916303/v1
Autor:
Nicholas van As, Bram Snijders, Scott Thomas Colville Shepherd, Steve Gamblin, Kate Young, Adrian Hayday, James Larkin, Ben Shum, Laura Amanda Boos, Phillip Hobson, Tim Slattery, Georgina H. Cornish, Ana Agua-Doce, Olivia Curtis, Joanne Droney, Mike Gavrielides, Alison Reid, Helen R. Flynn, Katalin A. Wilkinson, Anthony J. Swerdlow, James I. MacRae, Susana Banerjee, Lewis Au, Shreerang Bhide, Michael Howell, Martin Pule, Nicholas C. Turner, Robin L. Jones, Fiona Byrne, Spyridon Gennatas, Christina Messiou, Richard Stone, Liam Welsh, Yasir Khan, Zayd Tippu, Firza Gronthoud, Camilla Gomes, Ruth Harvey, Naureen Starling, Maddalena Cerrone, Sacheen Kumar, Wenyi Xie, Barry Ward, Alicia Okines, Kevin J. Harrington, George Kassiotis, Nadia Yousaf, Annika Fendler, Kevin W. Ng, Kate Tatham, Jerome Nicod, Emma Nye, Andrew Furness, Shaman Jhanji, Simon Caidan, David Cunningham, Leila Mekkaoui, Samra Turajlic, Charles Swanton, Camille L. Gerard, Robert L. Goldstone, Ian Chau, Jennifer Rusby, Emma Nicholson, Isla Leslie, Robert J. Wilkinson, Lisa Pickering, Sonia Ghandi
SUMMARYThere is a pressing need to characterise the nature, extent and duration of immune response to SARS-CoV-2 in cancer patients and inform risk-reduction strategies and preserve cancer outcomes. CAPTURE is a prospective, longitudinal cohort study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a28e61a8bd5ee40901ca8448ca9db7
https://doi.org/10.1101/2020.12.21.20248608
https://doi.org/10.1101/2020.12.21.20248608
Autor:
Shreerang Bhide, Jordan Cheng, Hisham Mehanna, Karl Payne, Feng Li, Paul Nankivell, Yong Kim, Daniele Borsetto, Nikolas Batis, Kanishka Rao, David T.W. Wong
Publikováno v:
Critical reviews in oncogenesis. 23(3-4)
Head and neck squamous cell carcinoma (HNSCC) manifests in the mucosal epithelial lining of the oral cavity, oropharynx, hypopharynx, nasopharynx or larynx and has a tremendous disease burden worldwide. Smoking and alcohol consumption were once major
Autor:
Shreerang Bhide, Richard G. Vile, Georges Vassaux, Kevin J. Harrington, Shane Zaidi, Christopher M. Nutting, C L White, Mohan Hingorani, Hardev Pandha, Konstantinos N. Syrigos, Alan Melcher
Publikováno v:
Molecular Therapy. 18:1599-1605
Adenoviral (AdV) transfer of sodium iodide symporter (NIS) gene has translational potential, but relatively low levels of transduction and subsequent radioisotope uptake limit the efficacy of the approach. In previous studies, we showed that combinin
Autor:
Shreerang Bhide, Martin McLaughlin, Robert Huddart, Suzanne A. Eccles, Christopher M. Nutting, Kevin J. Harrington, Shane Zaidi, Paul Workman
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35436 (2012)
PLoS ONE
PLoS ONE
Background Heat shock protein 90 (HSP90) is a molecular chaperone responsible for the conformational maintenance of a number of client proteins that play key roles in cell cycle arrest, DNA damage repair and apoptosis following radiation. HSP90 inhib
Autor:
Laura Vidal, Fiona Errington, C L White, Richard G. Vile, Kevin J. Harrington, Katie Twigger, Hardev Pandha, Johann S. de Bono, Brad Thompson, Shreerang Bhide, Alan Melcher, Matthew C. Coffey, Lucy Heinemann
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(3)
Purpose: To test combination treatment schedules of reovirus and radiation in human and murine tumor cells in vitro and in vivo. Experimental Design: In vitro cytotoxicity and cell cycle effects of reovirus given alone and combined with radiotherapy
Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo
Autor:
Alan Melcher, Katie Twigger, Richard G. Vile, T Menghistu, Kevin J. Harrington, Hardev Pandha, C L White, Peter F. Searle, Shreerang Bhide
Publikováno v:
Gene therapy. 15(6)
Escherichia coli nitroreductase (NTR) converts the prodrug CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide) into a bifunctional alkylating agent that causes DNA crosslinks. In this study, the ability of NTR to enhance the combined effects of CB1954 an
Autor:
Victoria Roulstone, Gerard J. Nuovo, Brad Thompson, Konstantinos N. Syrigos, Shreerang Bhide, Eleni M. Karapanagiotou, Richard Morgan, Alan Melcher, Fiona Errington, Joan N. Kyula, Adel Jebar, Katie Twigger, Matthew C. Coffey, Kevin J. Harrington, Richard G. Vile, Hardev Pandha, C L White
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 368 (2012)
BMC Cancer, Vol 12, Iss 1, p 368 (2012)
Background Reovirus exploits aberrant signalling downstream of Ras to mediate tumor-specific oncolysis. Since ~90% squamous cell carcinomas of the head and neck (SCCHN) over-express EGFR and SCCHN cell lines are sensitive to oncolytic reovirus, we co