Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shaney L. Barratt"'
Autor:
Nazia Chaudhuri, Timothy Wallis, Laura Horgan, David J.F. Smith, Thomas Simpson, Philip L. Molyneaux, Sophie V. Fletcher, Philippa Hallchurch, Muhunthan Thillai, Ieva Jakaityte, Katherine Myall, Stefan Stanel, Louise E. Crowley, Thomas Lewis, Tom McLellan, Fiona Thompson, Zhe Wu, Ryan Miller, Michael A Gibbons, Alex West, Paul Beirne, Shaney L Barratt, Anjali Crawshaw
Publikováno v:
The European Respiratory Journal
article-version (VoR) Version of Record
Simpson, T, Barratt, S L, Beirne, P, Chaudhuri, N, Crawshaw, A, Crowley, L E, Fletcher, S, Gibbons, M A, Hallchurch, P, Horgan, L, Jakaityte, I, Lewis, T, McLellan, T, Myall, K J, Miller, R, Smith, D J F, Stanel, S, Thillai, M, Thompson, F, Wallis, T, Wu, Z, Molyneaux, P L & West, A G 2021, ' The burden of Progressive Fibrotic Interstitial lung disease across the UK ', The European respiratory journal, vol. 58, no. 1, 2100221 . https://doi.org/10.1183/13993003.00221-2021
article-version (VoR) Version of Record
Simpson, T, Barratt, S L, Beirne, P, Chaudhuri, N, Crawshaw, A, Crowley, L E, Fletcher, S, Gibbons, M A, Hallchurch, P, Horgan, L, Jakaityte, I, Lewis, T, McLellan, T, Myall, K J, Miller, R, Smith, D J F, Stanel, S, Thillai, M, Thompson, F, Wallis, T, Wu, Z, Molyneaux, P L & West, A G 2021, ' The burden of Progressive Fibrotic Interstitial lung disease across the UK ', The European respiratory journal, vol. 58, no. 1, 2100221 . https://doi.org/10.1183/13993003.00221-2021
While idiopathic pulmonary fibrosis (IPF) remains the exemplar progressive fibrotic lung disease, there remains a cohort of non-IPF fibrotic lung diseases (fILD) which adopt a similar clinical behaviour to IPF despite therapy [1]. This phenotypically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd009971d0303270dd63da2f1d7d778c
https://eprints.soton.ac.uk/478095/
https://eprints.soton.ac.uk/478095/
Autor:
Karen T Elvers, Adrian Oates, Shaney L Barratt, Anna J Morley, Nick A Maskell, Fergus Hamilton, Marie Attwood, Alasdair P. MacGowan, David T Arnold, Jorgen McKernon, Charmaine Donald, Alan R. Noel
Publikováno v:
Arnold, D T, Attwood, M, Barratt, S, Morley, A, Elvers, K T, McKernon, J, Donald, C, Oates, A, Noel, A, MacGowan, A, Maskell, N A & Hamilton, F W 2021, ' Predicting outcomes of COVID-19 from admission biomarkers : a prospective UK cohort study ', Emergency Medicine Journal, vol. 38, no. 7, pp. 543-548 . https://doi.org/10.1136/emermed-2020-210380
Emergency Medicine Journal : EMJ
Emergency Medicine Journal : EMJ
IntroductionCOVID-19 has an unpredictable clinical course, so prognostic biomarkers would be invaluable when triaging patients on admission to hospital. Many biomarkers have been suggested using large observational datasets but sample timing is cruci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a684ca0da12f3e78f08b037b644c6f70
https://research-information.bris.ac.uk/ws/files/289127273/DISCOVER_BMJem_resub2_CLEAN.pdf
https://research-information.bris.ac.uk/ws/files/289127273/DISCOVER_BMJem_resub2_CLEAN.pdf
Autor:
Marie Attwood, Karen T Elvers, Shaney L Barratt, David T Arnold, Alan R. Noel, Nick A Maskell, Alasdair P. MacGowan, Charmaine Donald, Jorgen McKernon, Fergus Hamilton, Anna J Morley, Adrian Oates
IntroductionCOVID-19 has an unpredictable clinical course so prognostic biomarkers would be invaluable when triaging patients on admission to hospital. Many biomarkers have been suggested using large observational datasets but sample timing is crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baea172a3805de3f5f2fbda68098e60f
https://doi.org/10.1101/2020.06.25.20137935
https://doi.org/10.1101/2020.06.25.20137935
Publikováno v:
Guilt by association: ILD genetics and co-morbidities.
Introduction The therapeutic management of CTD-ILD and idiopathic forms differs widely, thus accurate diagnosis is essential. Several myositis-specific and myositis-associated antibodies (MSA/MAA) are now detectable that may associate with ILD. We wi
Autor:
David O. Bates, Nicholas Beazley-Long, Richard P. Hulse, Sebastian Oltean, Maria Peiris-Pagès, Nikita Ved, Xi Ye, Rebecca R. Foster, Domingo J. Tortonese, Maria J. C. Machado, Steven J. Harper, Andrew V. Benest, Shaney L Barratt, Lucy F. Donaldson
Publikováno v:
Bates, D O, Beazley-Long, N, Benest, A, Ye, X, Ved, N, Hulse, R, Barratt, S, Machado, M, Donaldson, L F, Harper, S, Peiris-Pages, M, Tortonese, D, Oltean, S & Foster, R R 2018, ' Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators ', Comprehensive Physiology, vol. 8, no. 3, pp. 955-979 . https://doi.org/10.1002/cphy.c170015
Comprehensive Physiology
Comprehensive Physiology
The vascular endothelial growth factor (VEGF) family of proteins are key regulators of physiological systems. Originally linked with endothelial function, they have since become understood to be principal regulators of multiple tissues, both through
Publikováno v:
Placenta. 22:822-830
Placental trophoblasts undergo apoptosis as part of normal epithelial turnover and placental ageing. Classically, the induction of apoptosis in in vitro preparations has utilized the cytokines TNFalpha and IFNgamma and has been measured using the TUN
Autor:
Shaney L Barratt, Gavin I. Welsh, Thomas Blythe, Caroline Jarrett, Ann B. Millar, David O. Bates, Chris J. Scotton, Khadija Ourradi
Publikováno v:
Thorax. 70:A38.2-A39
Introduction VEGF has been implicated in the development of IPF. Alternative splicing of the VEGF-A gene generates numerous isoforms. The differential effects of these isoforms, in particular the VEGF-A xxx b family, thought to have several opposing
Autor:
Gavin I. Welsh, Caroline Jarrett, Shaney L Barratt, Ann B. Millar, Khadija Ourradi, David O. Bates, Thomas Blythe, Chris J. Scotton
Publikováno v:
Thorax. 69:A73-A73
Introduction VEGF has been implicated in the pathogenesis of IPF. Differential splicing of the VEGF gene produces an alternative family of isoforms (VEGF xxx b) that have anti-angiogenic properties, in contrast to conventional isoforms (VEGF xxx ). C
Autor:
Caroline Jarrett, Toby M. Maher, David O. Bates, Thomas Blythe, Khadija Ourradi, Gavin I. Welsh, Shaney L Barratt, Ann B. Millar
Publikováno v:
Thorax. 68:A139.2-A140
Introduction Vascular endothelial growth factor (VEGFA) has been implicated in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF). Two families of endogenous isoforms exist formed by alternative splicing of mRNA transcripts: the conventional pot
Autor:
Thomas Blythe, Ann B. Millar, Gavin I. Welsh, Khadija Ourradi, Caroline Jarrett, Shaney L Barratt
Publikováno v:
Thorax. 68:A1.2-A1
Vascular endothelial growth factor (VEGF) undergoes alternate splicing producing isoforms with differing functional effects. The most biologically active and extensively studied isoform is VEGF 165 . An isoform that causes inhibition of endothelial p