Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Samir K. Gupta"'
Autor:
Nicole Shepherd, Corlin Jewell, Ningjie Hu, Kai Yang, Daniel Byrd, Jimin Gao, Samir K. Gupta, Yanyan Xing, Jie Lan, Carole Kounga, Qigui Yu, Tohti Amet
Publikováno v:
Journal of Virology. 89:9393-9406
Both HIV-1 virions and infected cells use their surface regulators of complement activation (RCA) to resist antibody-dependent complement-mediated lysis (ADCML). Blockage of the biological function of RCA members, particularly CD59 (a key RCA member
Publikováno v:
Journal of Antimicrobial Chemotherapy. 70:2889-2893
OBJECTIVES The HIV NNRTI rilpivirine is being evaluated as a possible agent for HIV pre-exposure prophylaxis. We have recently shown that the NNRTI efavirenz may impair endothelial function assessed as flow-mediated dilation (FMD), but whether this i
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 68:550-553
The relationships between HIV infection, monocyte activation, and endothelial colony forming cells (ECFCs) are unknown. We compared ECFC, intermediate monocytes (CD14+CD16+), and non-classical monocytes (CD14dimCD16++) levels in HIV-infected particip
Autor:
Hongji Zhang, Takashi Hato, Zeruesenay Desta, Todd C. Skaar, Samir K. Gupta, Michael T. Eadon, Pierre C. Dagher
Publikováno v:
Antiviral Chemistry and Chemotherapy. 24:72-76
BackgroundThe integrase inhibitors, raltegravir and dolutegravir, are nucleoside reverse transcriptase inhibitor-sparing agents which may be used as part of first-line antiretroviral therapy for HIV. These drugs inhibit creatinine secretion through o
Autor:
Luis J. Montaner, Young Min Son, Samir K. Gupta, Tohti Amet, In Su Cheon, Li Jiang, Jie Sun, Alexander L. Dent, Su Huang, Qigui Yu
Follicular Th (Tfh) cells are a distinct subset of Th cells that help B cells produce class-switched antibodies. Studies have demonstrated that Tfh cells are highly prone to HIV infection and replication. However, the molecular mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679d83c252f3a7a93e8e75952cb33bb8
https://europepmc.org/articles/PMC5505751/
https://europepmc.org/articles/PMC5505751/
Autor:
Sushmita Rane, Samir K. Gupta, Yanyan Xing, Shanxiang Zhang, Wei Li, Jie Lan, Nicole Shepherd, Jun Dong, Qigui Yu
HIV-1-associated neurocognitive disorders (HAND) continue to be a major concern in the infected population, despite the widespread use of combined antiretroviral therapy (cART). Growing evidence suggests that an imbalance between matrix metalloprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17813c845b5b9798912d85ce1c4213a
https://europepmc.org/articles/PMC5793222/
https://europepmc.org/articles/PMC5793222/
Autor:
Matthias Clauss, Chul Kim, Jalees Rehman, Linden A. Green, Gangaraju Rajashekhar, Samir K. Gupta
Publikováno v:
AIDS Research and Human Retroviruses. 28:1207-1215
Untreated HIV infection is associated with endothelial dysfunction and subsequent cardiovascular disease, likely due to both direct effects of the virus and to indirect effects of systemic inflammation on the vasculature. We have recently shown that
Autor:
Brian Taylor, Maja Deuter-Reinhard, Matthias Clauss, Linden Green, Samir K. Gupta, Zeruesenay Desta, Chul Wook Kim
Publikováno v:
Antiviral Therapy. 16:1335-1339
Background The use of abacavir and didanosine in HAART has been associated with an increased risk of myocardial infarction in HIV-infected patients. The aim of this study was to address the development of endothelial dysfunction in cultivated coronar
Publikováno v:
European Journal of Clinical Pharmacology. 67:591-599
To examine the effect of pegylated interferon (PEG-IFN) alfa-2b on the activity of major drug-metabolizing enzymes. This nonrandomized, open-label, multiple-dose study examined the effects of PEG-IFN alfa-2b on the activity of CYP450 1A2, 2 C8/9, 2D6
Autor:
Laura Moran, Lynne Jones, Judith A. Aberg, John W. Mellors, Marisa Tungsiripat, James F. Rooney, Samir K. Gupta, Beverly Alston-Smith, Douglas Kitch, Marshall J. Glesby
Publikováno v:
AIDS. 24:1781-1784
Several studies have reported improvement in lipids after antiretroviral therapy switches to tenofovir disoproxil fumarate (TDF)-containing regimens. We assessed lipid-lowering effects of TDF by adding it to a stable antiretroviral therapy regimen in