Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pilar Gutiérrez"'
Autor:
Swathi Sudhakar, Erin Cutts, Christopher Cawood, Luis Aragón, David Rueda, Pilar Gutiérrez-Escribano, Gemma Lm Fisher, Jonay García-Luis
Condensin plays a central role in the organisation of chromosomes by compacting chromatin into loops during mitosis. Condensin achieves this through a loop extrusion mechanism that remains poorly understood. To identify the molecular steps of yeast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d3dcadcd67524c8d3f4243dc2c07ba
https://doi.org/10.21203/rs.3.rs-901482/v1
https://doi.org/10.21203/rs.3.rs-901482/v1
Autor:
José Alonso Aguilar-Velázquez, Carolina del Pilar Gutiérrez-González, Héctor Rangel-Villalobos, Mayra Elizabeth García-Aceves, Gabriela Martínez-Cortés
Publikováno v:
Forensic Science International: Genetics Supplement Series. 7:617-619
We report three peculiar motherless paternity cases received in our lab at consecutive months, which involved four father-child mismatches for Penta E, the autosomal STR loci included in the Powerplex Fusion system. In all these cases, based on the r
Autor:
Eva Merino, Luis Aragón, Holger Kramer, Esmeralda Alonso-Rodríguez, Alex Montoya, Andrés Clemente-Blanco, María Teresa Villoria, Pilar Gutiérrez-Escribano, Adrián Campos, Facundo Ramos
Publikováno v:
Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The role of Rad53 in response to a DNA lesion is central for the accurate orchestration of the DNA damage response. Rad53 activation relies on its phosphorylation by Mec1 and its own autophosphorylation in a manner dependent on the adaptor Rad9. Whil
Autor:
Pilar Gutiérrez-Escribano, Matteo Allegretti, Jan Löwe, Francis J. O’Reilly, Christopher Cawood, Luis Aragón, Ludwig Sinn, Martin Beck, Byung-Gil Lee, Christian H. Haering, Léa Lecomte, Juri Rappsilber, Fabian Merkel, Takanori Nakane, Sol Bravo, Markus Hassler, Marc Kschonsak
Publikováno v:
Nat Struct Mol Biol
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology
Complexes containing a pair of structural maintenance of chromosomes (SMC) family proteins are fundamental for the three-dimensional (3D) organization of genomes in all domains of life. The eukaryotic SMC complexes cohesin and condensin are thought t
Autor:
Mohammad M. Karimi, Jonay García-Luis, Mar Sánchez, Luis Aragón, Luciana Lazar-Stefanita, Pilar Gutiérrez-Escribano, Adam Jarmuz, Axel Cournac, Alicia García, Alex Montoya, Sara Serrate González, Francisco Antequera, Holger B. Kramer, Marian Dore, Agnès Thierry, Romain Koszul
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature Structural & Molecular Biology
Digital.CSIC. Repositorio Institucional del CSIC
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Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biology
Nature Structural and Molecular Biology, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature Structural & Molecular Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biology
Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here, we show that the role of cohesin in chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff873f2a495cde66beec1322917ac14
https://hal-pasteur.archives-ouvertes.fr/pasteur-02866764
https://hal-pasteur.archives-ouvertes.fr/pasteur-02866764
Autor:
Marian Dore, Pilar Gutiérrez-Escribano, Alicia García, Francisco Antequera, Jonay García-Luis, Romain Koszul, Luciana Lazar-Stefanita, Adam Jarmuz, Mohammad M. Karimi, Luis Aragón, Agnès Thierry, Alex Montoya, Mar Sánchez, Holger B. Kramer, Sara Serrate González
Cohesin is a key regulator of genome architecture with roles in sister chromatid cohesion 1,2 and the organisation of higher-order structures during interphase 3 and mitosis 4,5. The recruitment and mobility of cohesin complexes on DNA is restricted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa3a0306cf15a0114e1eaa9a97eebbe
https://doi.org/10.1101/756601
https://doi.org/10.1101/756601
Autor:
Jonas Huber, Aida Llauró, Matthew D. Newton, Isabel Aly, Johannes Stigler, Pilar Gutiérrez-Escribano, Alex Montoya, Luis Aragón, David Rueda, Joseph Davy, Holger Kramer, Ricardo Aramayo, Loredana Tanasie
Essential processes such as accurate chromosome segregation, regulation of gene expression and DNA repair rely on protein-mediated DNA tethering. Sister chromatid cohesion requires the SMC complex cohesin to act as a protein linker that holds replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17379eb4c9fe29fb03bb95fefc57cc29
https://doi.org/10.1101/757286
https://doi.org/10.1101/757286
Autor:
Pilar Gutiérrez-Escribano, Luis Aragón, Roger Solé-Soler, Mariel Zapatka, Irene Pociño-Merino, Ralf Erik Wellinger, Neus Colomina, Hayat Heluani-Gahete, Celia Casas, Marcelino Bermúdez-López, Jordi Torres-Rosell, Sonia Apostolova, Eva Ibars, Marc Tarrés
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Cell Reports, Vol 29, Iss 10, Pp 3160-3172.e4 (2019)
Recercat. Dipósit de la Recerca de Catalunya
Repositorio Abierto de la UdL
Universitad de Lleida
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, Vol 29, Iss 10, Pp 3160-3172.e4 (2019)
Recercat. Dipósit de la Recerca de Catalunya
Repositorio Abierto de la UdL
Universitad de Lleida
Digital.CSIC. Repositorio Institucional del CSIC
Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms to tolerate DNA lesions. The Smc5/6 complex, together with the Nse2/Mms21 SUMO ligase, plays essential roles in genome stability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f02856982fc8577407c72de49e36308
http://www.cell.com/article/S2211124719314561/pdf
http://www.cell.com/article/S2211124719314561/pdf
Autor:
Luis Aragón, Andrés Clemente-Blanco, María Teresa Villoria, Eva Merino, Pilar Gutiérrez-Escribano, Facundo Ramos, Alex Montoya, Esmeralda Alonso-Rodríguez, Holger Kramer
The role of Rad53 in response to a DNA lesion is central for the accurate orchestration of the DNA damage response. Rad53 activation relies on its phosphorylation by the Mec1 kinase and its own auto-phosphorylation in a manner dependent on the adapto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc91be648b2e57019f08a84dbe4cde1
https://doi.org/10.1101/470427
https://doi.org/10.1101/470427
Autor:
Clara Aicart-Ramos, Fernando Moreno-Herrero, Pilar Gutiérrez-Escribano, Holger B. Kramer, Juri Rappsilber, Alex Montoya, Roger Solé-Soler, Kyle L. Morris, Silvia Hormeño, Jordi Torres-Rosell, Francis J. O’Reilly, Luis Aragón, Julene Madariaga-Marcos, Ricardo Aramayo
Publikováno v:
Molecular Cell
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Gutierrez-Escribano, P, Hormeño, S, Madariaga-Marcos, J, Solé-Soler, R, O’Reilly, F J, Morris, K, Aicart-Ramos, C, Aramayo, R, Montoya, A, Kramer, H, Rappsilber, J, Torres-Rosell, J, Moreno-Herrero, F & Aragon, L 2020, ' Purified Smc5/6 complex exhibits DNA substrate recognition and compaction ', Molecular Cell, vol. 80, no. 6, pp. 1039-1054.e6 . https://doi.org/10.1016/j.molcel.2020.11.012
Digital.CSIC. Repositorio Institucional del CSIC
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Gutierrez-Escribano, P, Hormeño, S, Madariaga-Marcos, J, Solé-Soler, R, O’Reilly, F J, Morris, K, Aicart-Ramos, C, Aramayo, R, Montoya, A, Kramer, H, Rappsilber, J, Torres-Rosell, J, Moreno-Herrero, F & Aragon, L 2020, ' Purified Smc5/6 complex exhibits DNA substrate recognition and compaction ', Molecular Cell, vol. 80, no. 6, pp. 1039-1054.e6 . https://doi.org/10.1016/j.molcel.2020.11.012
Digital.CSIC. Repositorio Institucional del CSIC
Repositorio Abierto de la UdL
Universitad de Lleida
Summary Eukaryotic SMC complexes, cohesin, condensin, and Smc5/6, use ATP hydrolysis to power a plethora of functions requiring organization and restructuring of eukaryotic chromosomes in interphase and during mitosis. The Smc5/6 mechanism of action