Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Nam-Soon Kim"'
Autor:
Soo Young Jun, Min Hyuk Choi, Su Jin Jeon, Joon Won Kang, Ju-Sik Min, Iksu Byeon, Jeong Ju Lee, Nam-Soon Kim, Ji Yong Yoon, Jin Ok Yang, Yong Jae Lee
Publikováno v:
Genetic Testing and Molecular Biomarkers. 24:54-58
Aim: Lennox-Gastaut syndrome (LGS) is a severe type of childhood-onset epilepsy with multiple types of seizures, specific discharges on electroencephalography, and intellectual disability. However, LGS-related genes are largely unknown. To identify c
Autor:
Young-Kyoung Ryu, Tae Kyung Kim, Jae-Ran Lee, ChiHye Chung, Jeong Yeob Baek, Nam-Soon Kim, Rumeysa Dogan, Jahong Koo, Dahun Um, Won-Ho Shin, Bohyeon Jeong, Hyung-Seok Choi, Jinyoung Jeong, Seungjae Zhang, Kyoung-Shim Kim, Subin Park, Da Yong Lee, Wang Sik Lee
Publikováno v:
Journal of hazardous materials. 426
As global plastic production continues to grow, microplastics released from a massive quantity of plastic wastes have become a critical environmental concern. These microplastic particles are found in a wide range of living organisms in a diverse arr
Autor:
Jeong-Ju Lee, Jin-Man Kim, Soo Young Jun, Su-Jin Jeon, Ji-Yong Yoon, Nam-Soon Kim, Debasish Halder, Hyang Ran Yoon
Publikováno v:
Cancers, Vol 13, Iss 2925, p 2925 (2021)
Cancers
Volume 13
Issue 12
Cancers
Volume 13
Issue 12
Simple Summary We recently reported that the human TOR signaling regulator (hereafter TIPRL) contributes to the drug-resistance of hepatocellular carcinomas (HCCs) and the involvement of TIPRL/LC3/CD133 in liver cancer aggressiveness. This study aims
Autor:
Jeong-Ju Lee, Debasish Halder, Duk Hyun Sung, Byoung Joon Kim, Sohyun Yun, Su-Jin Jeon, Jin Myoung Seok, Nam-Soon Kim, Jung Kyoon Choi, Eui-Jeon Woo, Ja-Hyun Jang, Jin Ok Yang, Jin Whan Cho, Ji-Yong Yoon, Soo Young Jun
Publikováno v:
Genomics. 113(6)
Hereditary Spastic Paraplegias (HSP) are a group of rare inherited neurological disorders characterized by progressive loss of corticospinal motor-tract function. Numerous patients with HSP remain undiagnosed despite screening for known genetic cause
Autor:
Jae-Ran Lee, Tae Hwan Kim, Nam-Soon Kim, Won-Ho Shin, Dae-Soo Kim, Da Yong Lee, Bohyeon Jeong
Publikováno v:
Neuroscience. 411:76-85
Spastin is a microtubule-severing enzyme encoded by SPAST, which is broadly expressed in various cell types originated from multiple organs. Even though SPAST is well known as a regulator of the axon growth and arborization in neurons and a genetic f
Autor:
Byoung Joon Kim, Duk Hyun Sung, Hong-Ryul Jung, Nam-Soon Kim, Cho-Rok Jung, Hyun Mi Kang, Kyung-Sook Chung, Jung Hwa Lim, Tae Kyung Chang, Dae-Soo Kim, Hyun-Soo Cho, Kyung Hee Noh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3221-3233
The spastin protein (SPAST) contains an ATPase with diverse cellular activities (AAA) domain and regulates microtubule dynamics. Missense mutations of the SPAST gene are frequently detected in patients with hereditary spastic paraplegias (HSPs) and r
Autor:
Debasish Halder, Byungwook Lee, Soo Young Jun, Sohyun Yun, Min-Hyuk Choi, Jeong-Ju Lee, Ji-Yong Yoon, Iksu Byeon, Juhyun Kong, Sang Ook Nam, Joon Won Kang, Nam-Soon Kim, Su-Jin Jeon, Jeehun Lee, Hyeok Hee Kwon, Jin Ok Yang
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2021)
Frontiers in Genetics, Vol 11 (2021)
Lennox-Gastaut syndrome (LGS) is a severe type of childhood-onset epilepsy characterized by multiple types of seizures, specific discharges on electroencephalography, and intellectual disability. Most patients with LGS do not respond well to drug tre
Autor:
Jeong-Ju Lee, Min-Hyuk Choi, Debasish Halder, Cho-Rok Jung, Jung-Hwa Lim, Su-Jin Jeon, Jun-Ho Ahn, Nam-Soon Kim, Ji-Yong Yoon, Soo Young Jun, Jin-Man Kim, Hyun-Soo Cho
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-17 (2019)
Cell Death and Disease, Vol 10, Iss 12, Pp 1-17 (2019)
Autophagy, an intracellular system of degrading damaged organelles and misfolded proteins, is essential for cancer cell survival. Despite the progress made towards understanding the mechanism, identification of novel autophagy regulators presents a m
Autor:
Sugi Lee, Jea Woon Ryu, Jung-Hwa Oh, Jiwon Ahn, Ju-Sik Min, Hyun Mi Kang, Janghwan Kim, Kyung-Sook Chung, Mi Young Son, Jun Ho Ahn, Jeong Ju Lee, Nam-Soon Kim, Dae-Soo Kim, Hyun-Soo Cho, Cho Rok Jung
Publikováno v:
Hepatology (Baltimore, Md.)
Alternative cell sources, such as three-dimensional organoids and induced pluripotent stem cell-derived cells, might provide a potentially effective approach for both drug development applications and clinical transplantation. For example, the develo
Autor:
Yoo-Mi Kim, Jae-Ran Lee, Doyoun Kim, Eunjoon Kim, Tae-Sung Yoon, Na-Yoon Lee, Chong Kun Cheon, Nam-Soon Kim, So-Hee Lim
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
SCIENTIFIC REPORTS(7)
Scientific Reports
SCIENTIFIC REPORTS(7)
KIF1A is a brain-specific anterograde motor protein that transports cargoes towards the plus-ends of microtubules. Many variants of the KIF1A gene have been associated with neurodegenerative diseases and developmental delay. Homozygous mutations of K