Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Michael Lee"'
Autor:
Jason E. Miller, Manu Shivakumar, David J. Carey, Yanfei Zhang, Ming Ta Michael Lee, Radhika Gogoi, Venkata Ramesh Dasari, Dokyoon Kim
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 30:1681-1688
Background: Rare variants play an essential role in the etiology of cancer. In this study, we aim to characterize rare germline variants that impact the risk of cancer. Methods: We performed a genome-wide rare variant analysis using germline whole ex
Autor:
Cheng Cheng Zhang, Amanda E. Jones, John M. Abrams, Simon J. Newkirk, Giovanni A. Botten, Xun Wang, Wenfeng An, Jian Xu, Zhimin Gu, Yuannyu Zhang, Mi Deng, Hui Cao, Kathryn E. Dickerson, Michael Lee, Yuxuan Liu, Junhua Lyu, Annika Wylie
Publikováno v:
Nature Genetics. 53:672-682
Transposable elements or transposons are major players in genetic variability and genome evolution. Aberrant activation of long interspersed element-1 (LINE-1 or L1) retrotransposons is common in human cancers, yet their tumor-type-specific functions
Publikováno v:
BioResources. 16:2921-2936
The demand for timber resources in the building industry has been increasing. Plantation Eucalyptus nitens is of interest because of its sustainable supply and potential for structural applications. However, few design standards cover strength values
Autor:
Cédric Diot, Aurian P. García-González, Andre F. Vieira, Melissa Walker, Megan Honeywell, Hailey Doyle, Olga Ponomarova, Yomari Rivera, Huimin Na, Hefei Zhang, Michael Lee, Carissa P. Olsen, Albertha J.M. Walhout
Publikováno v:
Nature communications. 13(1)
Tamoxifen is a selective estrogen receptor (ER) modulator that is used to treat ER-positive breast cancer, but that at high doses kills both ER-positive and ER-negative breast cancer cells. We recapitulate this off-target effect in Caenorhabditis ele
Publikováno v:
Zootaxa. 5067(4)
In this paper, one new genus, Ptosoproctus gen. nov., is established with two new species: P. lanzhouensis sp. nov. and P. baishishanicus sp. nov., described and illustrated based on material collected from northern China. The genus Eulithoxenus Bey-
Autor:
Filip Jagodzinski, Milo Rupp, Michael Lee, Jordan D. Valgardson, Jeanine F. Amacher, Robin Cosbey, Paul Houser, Raiden Van Bronkhorst
Publikováno v:
Protein Sci
Recognition of short linear motifs (SLiMs) or peptides by proteins is an important component of many cellular processes. However, due to limited and degenerate binding motifs, prediction of cellular targets is challenging. In addition, many of these
Publikováno v:
Genes & Genomics. 41:1273-1280
Acquired resistance is a significant clinical challenge in targeted therapy of melanomas using BRAF inhibitors. We previously identified that downregulation of miR-92a-1-5p confers acquired resistance to BRAF inhibition using an miRNA array platform.
Autor:
Kevin R. Costello, Michael Lee, Mudasar Basam, J. Andrew Pospisilik, Dustin E. Schones, Candi Trac, Amy Leung
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes to have function, the majority of these elements are epigenetically silenced by DNA methyl
Publikováno v:
Cureus
Cutaneous Leishmaniasis due to Leishmania mexicana is a common cause of New World protozoal infections endemic to southern Mexico and now the United States (US). We present a case of a 72-year-old male who became infected with cutaneous L. mexicana w