Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Masahiro Hirakawa"'
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology, Vol 11 (2021)
Frontiers in immunology, 11:570550. Frontiers Media S.A.
Frontiers in Immunology
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology, Vol 11 (2021)
Frontiers in immunology, 11:570550. Frontiers Media S.A.
Frontiers in Immunology
Copyright © 2021 Matos, Hirakawa, Alho, Neleman, Graca and Ritz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d212f804dc42cd29f1bc575164c855
Autor:
Michihiro Ono, Masahiro Hirakawa, Koji Miyanishi, Takahiro Osuga, Kazuyuki Murase, Naoki Uemura, Yohei Arihara, Makoto Yoshida, Tsutomu Sato, Junji Kato, Yasushi Sato, Yutaka Okagawa, Fumito Tamura, Tsuyoshi Hayashi, Satoshi Iyama, Rishu Takimoto, Yutaka Kawano, Kohichi Takada, Masayoshi Kobune
Publikováno v:
Gastric Cancer. 19:85-97
ST6GalNAc I is a sialyltransferase controlling the expression of sialyl-Tn antigen (STn), which is overexpressed in several epithelial cancers, including gastric cancer, and is highly correlated with cancer metastasis. However, the functional contrib
Autor:
Kohichi Takada, Satoshi Iyama, Makoto Yoshida, Masahiro Hirakawa, Koji Miyanishi, Takahiro Osuga, Fumito Tamura, Yutaka Okagawa, Naoki Uemura, Yohei Arihara, Junji Kato, Masayoshi Kobune, Tsutomu Sato, Tsuyoshi Hayashi, Rishu Takimoto, Yasushi Sato, Michihiro Ono
Publikováno v:
Journal of the National Cancer Institute. 108(8)
BACKGROUND Fucose is utilized for the modification of different molecules involved in blood group determination, immunological reactions, and signal transduction pathways. We have recently reported that enhanced activity of the fucosyltransferase 3 a
Autor:
Masahiro Hirakawa, Koji Miyanishi, Kazuyuki Murase, Tsuyoshi Hayashi, Junji Kato, Masayoshi Kobune, Rishu Takimoto, Michihiro Ono, Kohichi Takada, Tsutomu Sato, Satoshi Iyama, Yasushi Sato, Takahiro Osuga, Masahiro Yoshida, Fumito Tamura
Publikováno v:
British Journal of Cancer
Background: Transforming growth factor-β (TGF-β) is a major inducer of epithelial–mesenchymal transition (EMT) in different cell types. TGF-β-mediated EMT is thought to contribute to tumour cell spread and metastasis. Sialyl Lewis antigens synth
Publikováno v:
Blood. 126:2357-2357
Introduction: CD4+ FoxP3+ CD25+ regulatory T cells (Treg) are required for maintenance of immune tolerance and immune homeostasis. Quantitative or functional Treg deficiency has been correlated with autoimmune disease, allergy, allograft rejection an
Autor:
Jennifer R. Brown, Masahiro Hirakawa, Tiago R. Matos, Siddha Kasar, Jerome Ritz, Benjamin L. Lampson, Stacey M. Fernandes
Publikováno v:
Blood. 126:1735-1735
Introduction: Idelalisib, a specific small molecule inhibitor of the delta isoform of PI3 kinase (PI3Kd), has recently been FDA approved for the treatment of relapsed CLL. Expression of PI3Kd is predominantly restricted to leukocytes, and inhibition
Autor:
Marie J Chammas, Jerome Ritz, Eduardo Espada, Carol Reynolds, Kathy S. Wang, Kazuyuki Murase, Jennifer Whangbo, Tiago R. Matos, Edouard Forcade, Masahiro Hirakawa
Publikováno v:
Blood. 126:3425-3425
Introduction: Cytokines play important roles in the activation, proliferation, differentiation and survival of T cells. Previous studies have revealed that individual cytokines selectively activate different T cell populations and also function at sp
Autor:
Jerome Ritz, Yutaka Kawano, Haesook T. Kim, Anthony Letai, Robert J. Soiffer, John Koreth, Kazuyuki Murase, Masahiro Hirakawa, Junji Kato, Ken-ichi Matsuoka, Tiago R. Matos, Jeremy Ryan
Publikováno v:
Blood. 124:1414-1414
CD4+CD25+Foxp3+ regulatory T cells (Treg) play a critical role in establishment of immune tolerance and prevention of graft versus host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT). The recovery and maintenance of Tr
Autor:
Tsuyoshi Hayashi, Rishu Takimoto, Fumito Tamura, Masahiro Hirakawa, Makoto Yoshida, Koji Miyanishi, Satoshi Iyama, Kazuyuki Murase, Tsutomu Sato, Yasushi Sato, Takahiro Osuga, Junji Kato, Masayoshi Kobune, Kohichi Takada
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39545 (2012)
PLoS ONE
PLoS ONE
Owing to its aggressiveness and the lack of effective therapies, pancreatic ductal adenocarcinoma has a dismal prognosis. New strategies to improve treatment and survival are therefore urgently required. Numerous fucosylated antigens in sera serve as
Autor:
Masahiro Hirakawa, Kazuyuki Murase, Koji Miyanishi, Masayoshi Kobune, Yoshiyuki Onuma, Makoto Yoshida, Rishu Takimoto, Yasushi Sato, Tsutomu Sato, Junji Kato
Publikováno v:
Cancer Research. 70:3936-3936
Accumulating evidence suggests that DNA repair enzyme activity may predict sensitivity to chemotherapeutic agents in cancer cells. The status of a DNA repair enzyme, such as XPF/ERCC4 or XPD/ERCC2, has been reported to serve as a prognostic indicator