Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Martín, Hugo"'
Publikováno v:
Free radical biology and medicine, 160:293-302
The proteasomal degradation system is one of the most important protein degradation systems in the cytosol and nucleus. This system is present in two major forms: the ATP-stimulated 26S/30 S proteasome or the ATP-independent 20S core proteasome. Whil
Publikováno v:
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Antioxidants
Volume 9
Issue 2
R-USJ: Repositorio Institucional de la Universidad San Jorge
Universidad San Jorge (USJ)
Antioxidants, Vol 9, Iss 2, p 177 (2020)
instname
Antioxidants
Volume 9
Issue 2
R-USJ: Repositorio Institucional de la Universidad San Jorge
Universidad San Jorge (USJ)
Antioxidants, Vol 9, Iss 2, p 177 (2020)
Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries. The objective of this study was to determine the cytoprotective capacity of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2706ad09660711386a4f4cee902fecf2
http://zaguan.unizar.es/record/88583
http://zaguan.unizar.es/record/88583
Autor:
Tobias Jung, Daniela Weber, Tilman Grune, José Pedro Castro, Ioanna Korovila, Annika Höhn, Martín Hugo
Publikováno v:
Redox Biology
Redox Biology, Vol 13, Iss C, Pp 550-567 (2017)
Redox Biology, Vol 13, Iss C, Pp 550-567 (2017)
The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are
Autor:
Annika Höhn, Jeannette König, Martín Hugo, Tilman Grune, Anne-Laure Bulteau, Tobias Jung, Christiane Ott
Publikováno v:
Redox Biology, Vol 11, Iss, Pp 673-681 (2017)
Redox Biology
Redox Biology
Mitochondria have been in the focus of oxidative stress and aging research for decades due to their permanent production of ROS during the oxidative phosphorylation. The hypothesis exists that mitochondria are involved in the formation of lipofuscin,
Autor:
Anabel Marina, Tilman Grune, Martín Hugo, Markus Köhler, Carlos García-García, Ioanna Korovila, J. Daniel Cabrera-García, Antonio Martínez-Ruiz
Publikováno v:
Redox Biology
Redox Biology, Vol 16, Iss, Pp 123-128 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology, Vol 16, Iss, Pp 123-128 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Under oxidative stress 26S proteasomes suffer reversible disassembly into its 20S and 19S subunits, a process mediated by HSP70. This inhibits the degradation of polyubiquitinated proteins by the 26S proteasome and allows the degradation of oxidized
Autor:
Ohara Augusto, Madia Trujillo, Ari Zeida, Martín Hugo, Edlaine Linares, Damián Estrada, Alejandra Martínez, Mauricio Mastrogiovanni, Harry F. G. Heijnen, Lucía Piacenza, Federico Issoglio, Rafael Radi, Darío A. Estrin
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The Trypanosoma cruzi ascorbate peroxidase is, by sequence analysis, a hybrid type A member of class I heme peroxidases [TcAPx-cytochrome c peroxidase (CcP)], suggesting both ascorbate (Asc) and cytochrome c (Cc) peroxidase activity. Here, we show th
Autor:
Thiago Geronimo Pires Alegria, Napoleão Fonseca Valadares, Ohara Augusto, Paolo Di Mascio, Raphael Ferreira Queiroz, José Renato Rosa Cussiol, Rafael Radi, Richard Charles Garratt, Sayuri Miyamoto, Madia Trujillo, Martín Hugo, Diogo de Abreu Meireles, Marcos Antonio de Oliveira, Luis Eduardo Soares Netto
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Organic hydroperoxide resistance (Ohr) enzymes are unique Cys-based, lipoyl-dependent peroxidases. Here, we investigated the involvement of Ohr in bacterial responses toward distinct hydroperoxides. In silico results indicated that fatty acid (but no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121c48fff0ad4536a75d4d8cf1563254
Autor:
Madia Trujillo, Carlos Batthyány, Bruno Manta, Ana Denicola, Magdalena Gil, Lía M. Randall, Martín Hugo, Leslie B. Poole
Publikováno v:
Journal of Biological Chemistry. 289:15536-15543
Peroxiredoxins (Prx) are efficient thiol-dependent peroxidases and key players in the mechanism of H2O2-induced redox signaling. Any structural change that could affect their redox state, oligomeric structure, and/or interaction with other proteins c
Autor:
Diego S. Vazquez, Madia Trujillo, Martín Hugo, Rafael Radi, Javier Santos, Darío A. Estrin, María Inés De Armas, M. Dolores Piñeyro, Aníbal M. Reyes, Ari Zeida
Publikováno v:
Advances in Free Radical Biology & Medicine
Advances in Free Radical Biology & Medicine, Elsevier, 2015, 101, pp.249-260. ⟨10.1016/j.freeradbiomed.2016.10.005⟩
Advances in Free Radical Biology & Medicine, Elsevier, 2015, 101, pp.249-260. ⟨10.1016/j.freeradbiomed.2016.10.005⟩
Mycobacterium tuberculosis (M. tuberculosis) is the intracellular bacterium responsible for tuberculosis disease (TD). Inside the phagosomes of activated macrophages, M. tuberculosis is exposed to cytotoxic hydroperoxides such as hydrogen peroxide, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042d66280e8ec1abf7a3e210176328d6
https://www.sciencedirect.com/science/article/pii/S0891584916304476
https://www.sciencedirect.com/science/article/pii/S0891584916304476