Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marie Houllier"'
Autor:
Anne-Marie Houllier, Hélène Blons, Pierre Laurent-Puig, Delphine Le Corre, Aurélie Cazes, Karine Pallier
Publikováno v:
Molecular Carcinogenesis. 48:581-585
The paxillin gene (PXN) encodes a focal adhesion associated protein that could be involved in the progression of lung cancer through its interactions with the actin cytoskeleton and key signal transduction oncogenes. PXN mutations and PXN amplificati
Autor:
P Beaune, Pierre Laurent-Puig, Ollivier Laccourreye, Anne-Marie Houllier, Astrid Lièvre, Daniel Brasnu, Hélène Blons
Publikováno v:
British Journal of Cancer
Mitochondrial DNA mutations have been reported in several types of tumours, including head and neck squamous cell carcinoma (HNSCC). The noncoding region of the Displacement-Loop (D-Loop) has emerged as a mutational hotspot and we recently found that
Autor:
Anne-Marie Houllier, Henri Kreis, Laure-Hélène Noël, Eric Thervet, Philippe Beaune, Dany Anglicheau, Nathalie Toledano, Christophe Legendre
Publikováno v:
Journal of the American Society of Nephrology. 12:170-176
Thiopurine methyltransferase (TPMT) is implicated in the metabolism of azathioprine. The consequences of dif- ferential TPMT activity induction by azathioprine on the long- term results after renal transplantation were investigated. The erythrocyte T
Autor:
Pierre Laurent-Puig, Philippe Beaune, Françoise Carnot, Ollivier Laccourreye, Anne-Marie Houllier, Jessica Zucman-Rossi, Hélène Blons, Daniel Brasnu
Publikováno v:
Oncogene. 21(32)
The 18q chromosome arm is frequently lost in advanced head and neck squamous cell carcinoma. Twenty-four microsatellite markers located on chromosome 18q were genotyped in 145 primary tumors and 10 cell lines in order to identify putative tumor suppr
Publikováno v:
Immunology letters. 30(3)
The human lymphoblast cell line Jurkat is widely used as a model system for studying signal transduction pathways during lymphocyte activation. We report the presence of a potent endogenous inhibitor of protein kinase C (PKC) in the cytosolic fractio
Autor:
Laure Thuilier, Hélène A. Buc, Michèle Hamet, Jean-Luis Perignon, Anne-Marie Houllier, Arlette Moncion
Publikováno v:
European journal of immunology. 20(3)
An experimental model of adenosine deaminase deficiency was established on the human T cell line Jurkat by using 2'-deoxycoformycin, a strong specific inhibitor of the enzyme. When deoxyadenosine was added to the inhibited cells, the nucleotide profi
Autor:
Anne-Marie Houllier, Laure Thuillier, Guy Leverger, Jean-Louis Pérignon, Jacques Chaléon, Cartier P
Publikováno v:
Clinica Chimica Acta. 147:67-74
Cytidine deaminase activity was determined by a radioisotopic assay in extracts of peripheral blood mononuclear cells of normal individuals and of patients with acute lymphoblastic leukaemia. The normal enzyme activity had a broad pH optimum between
Autor:
Jean-Louis Pérignon, Anne-Marie Houllier, Michèle Hamet, Pierre-Hubert Cartier, Laure Thuillier
Publikováno v:
International Journal of Immunopharmacology. 8:427-431
The intermediary metabolism of pyrimidine nucleosides was studied in a line of human B lymphoblasts (Raji) in which pyrimidine de novo synthesis deficiency was pharmacologically induced by pyrazofurin. It was found that Raji cells are cytidine deamin
Publikováno v:
Biochimica et biophysica acta. 798(3)
We studied the ability of purine compounds to restore the proliferation of concanavalin-A-stimulated rat T-lymphocytes under conditions of purine de novo synthesis inhibition and, on the other hand, the inhibition by purine nucleosides of the respons