Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manlu, Zhu"'
Publikováno v:
Science China Life Sciences. 64:795-802
Bacteria growth depends crucially on protein synthesis, which is limited by ribosome synthesis. Ribosomal RNA (rRNA) transcription is the rate-limiting step of ribosome synthesis. It is generally proposed that the transcriptional initiation rate of r
Autor:
Manlu Zhu, Xiongfeng Dai
Publikováno v:
Trends in Biochemical Sciences. 45:681-692
Ribosome and protein synthesis lie at the core of cell growth and are major consumers of the cellular budget. Here we review recent progress in the coupling of ribosome synthesis and translational capacity with cell growth in bacteria. We elaborate o
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103333-(2021)
Summary Tight coordination between transcription and translation has long been recognized as the hallmark of gene expression in bacteria. In Escherichia coli cells, disruption of the transcription-translation coordination leads to the loss of transcr
Autor:
Xiongfeng Dai, Manlu Zhu
Publikováno v:
Critical Reviews in Microbiology. 44:455-464
In nature, the maximal growth rates vary widely among different bacteria species. Fast-growing bacteria species such as Escherichia coli can have a shortest generation time of 20 min. Slow-growing bacteria species are perhaps best known for Mycobacte
Autor:
Xiongfeng Dai, Manlu Zhu
Publikováno v:
Cellular and molecular life sciences : CMLS. 77(5)
In nature, bacteria are constantly adapting to various stressful conditions. Timely activation of stress response programs is crucial for bacteria to smoothly survive under stressful conditions. Stress response, demanding the de novo synthesis of man
Autor:
Xiongfeng Dai, Manlu Zhu
Publikováno v:
Nucleic Acids Research
To cope with harsh circumstances, bacterial cells must initiate cellular stress response programs, which demands the de novo synthesis of many stress defense proteins. Reactive oxygen species (ROS) is a universal environmental stressor for both proka
Publikováno v:
Current genetics. 65(5)
A fundamental question in microbiology is how bacterial cells manage to coordinate gene expression with cell growth during adapting to various environmental conditions. Although the cellular responses to changing environments have been extensively st
Autor:
Manlu Zhu, Xiongfeng Dai
Publikováno v:
Nucleic Acids Research
Understanding how bacteria coordinate gene expression with biomass growth to adapt to various stress conditions remains a grand challenge in biology. Stress response is often associated with dramatic accumulation of cellular guanosine tetra- or penta
Publikováno v:
mSphere, Vol 3, Iss 6, p e00567-18 (2018)
mSphere, Vol 3, Iss 6 (2018)
mSphere
mSphere, Vol 3, Iss 6 (2018)
mSphere
The dependence of cell size on growth rate is a fundamental principle in the field of bacterial cell size regulation. Previous studies of cell size regulation mainly focus on fast-growing bacterial species such as Escherichia coli and Bacillus subtil
Publikováno v:
mSphere, Vol 3, Iss 2 (2018)
mSphere, Vol 3, Iss 2, p e00095-18 (2018)
mSphere, Vol 3, Iss 2, p e00095-18 (2018)
Environmental stresses often co-occur when bacteria encounter antibiotic treatment inside the human body. The cellular response to environmental stressors can alter the global gene expression pattern of bacteria. However, the relationship between the