Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Manabu, Igarashi"'
Publikováno v:
PeerJ Physical Chemistry, Vol 3, p e19 (2021)
The substitution of Ile to Val at residue 117 (I117V) of neuraminidase (NA) reduces the susceptibility of the A/H5N1 influenza virus to oseltamivir (OTV). However, the molecular mechanism by which the I117V mutation affects the intermolecular interac
Autor:
Shiho Torii, Tsogtbaatar Urangoo, Keita Matsuno, Yoshihiro Takadate, Khanui Buyantogtokh, Takeshi Saito, Kosuke Okuya, Ankhanbaatar Ulaankhuu, Khishgee Bodisaikhan, Takanari Hattori, Masatoshi Okamatsu, Manabu Igarashi, Yoshihiro Sakoda, Jargalsaikhan Tserenjav, Damdinjav Batchuluun, Yurie Kida, Hiroshi Kida, Mao Isono, Junki Maruyama, Tsolmon Amartuvshin, Masahiro Sato, Enkhbold Bazarragchaa, Takahiro Hiono, Ayato Takada, Tatsunari Kondoh, Nodoka Kasajima
Publikováno v:
Virus Genes
The circulation of highly pathogenic avian influenza viruses (HPAIVs) of various subtypes (e.g., H5N1, H5N6, H5N8, and H7N9) in poultry remains a global concern for animal and public health. Migratory waterfowls play important roles in the transmissi
Autor:
Kengo Kawachi, Masayuki Shimojima, Miyuki Kimura, Shigeru Morikawa, Manabu Igarashi, Hideki Tani, Masayuki Saijo, Satoshi Taniguchi, Shuetsu Fukushi
Publikováno v:
Virology. 535:102-110
Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease with a high fatality rate, caused by SFTS virus (SFTSV). Because little is known about the nature of SFTSV, basic studies are required for the developments of vaccines and ef
Autor:
Taksoo Kim, Manabu Igarashi, Shizuka Hirose, Norikazu Isoda, Yoshihiro Sakoda, Loc Tan Huynh, Takahiro Hiono
Publikováno v:
Viruses, Vol 13, Iss 1672, p 1672 (2021)
Viruses
Volume 13
Issue 8
Viruses
Volume 13
Issue 8
The GPE− strain is a live attenuated vaccine for classical swine fever (CSF) developed in Japan. In the context of increasing attention for the differentiating infected from vaccinated animals (DIVA) concept, the achievement of CSF eradication with
Publikováno v:
PeerJ
PeerJ, Vol 9, p e11552 (2021)
PeerJ, Vol 9, p e11552 (2021)
Background Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA reduces its binding affinity to OTV have not been
Autor:
Hiroko Miyamoto, Ayato Takada, Reiko Yoshida, Rashid Manzoor, Yoshihiro Takadate, Masahiro Kajihara, Junki Maruyama, Hirohito Ogawa, Wakako Furuyama, Tatsunari Kondoh, Masahiro Sato, Naganori Nao, Manabu Igarashi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Two novel influenza A virus-like genomes were detected in fruit bats in Central and South America. However, the biological properties of these bat-derived influenza viruses (BatIVs) are still largely unknown since infectious viral particles have neve
Autor:
Katherine M Fuller, Erica Ollmann Saphire, Manabu Igarashi, Ayato Takada, Diptiben V. Parekh, Jacob C. Milligan
Publikováno v:
The Journal of Infectious Diseases. 219:415-419
Ebola virus infection causes severe disease in humans and represents a global health threat. Candidates for immunotherapeutics and vaccines have shown promise in clinical trials, although they are ineffective against other members of the Ebolavirus g
Autor:
Yoshimi Tsuda, Jiro Arikawa, Kumiko Yoshimatsu, Manabu Igarashi, Fumiya Kozawa, Kisho Noda, Kenta Shimizu
Publikováno v:
Viruses
Volume 13
Issue 1
Viruses, Vol 13, Iss 33, p 33 (2021)
Volume 13
Issue 1
Viruses, Vol 13, Iss 33, p 33 (2021)
Severe fever with thrombocytopenia syndrome virus subclone B7 shows strong plaque formation and cytopathic effect induction compared with other subclones and the parental strain YG1. Compared to YG1 and the other subclones, only B7 possesses a single
Autor:
Hiroki Atarashi, Wikum Harshana Jayasinghe, Joon Kwon, Hangil Kim, Yosuke Taninaka, Manabu Igarashi, Kotaro Ito, Tetsuya Yamada, Chikara Masuta, Kenji S. Nakahara
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology
Eukaryotic translation initiation factors, including eIF4E, are susceptibility factors for viral infection in host plants. Mutation and double-stranded RNA-mediated silencing of tomato eIF4E genes can confer resistance to viruses, particularly member
Autor:
Takeshi Saito, Yoshihiro Takadate, Rashid Manzoor, Hiroko Miyamoto, Manabu Igarashi, Ayato Takada, Yurie Kida, Hirohito Ogawa, Junki Maruyama, Masahiro Kajihara, Tatsunari Kondoh
Publikováno v:
Microorganisms, Vol 8, Iss 1530, p 1530 (2020)
Microorganisms
Volume 8
Issue 10
Microorganisms
Volume 8
Issue 10
Lloviu virus (LLOV), a bat-derived filovirus that is phylogenetically distinct from human pathogenic filoviruses such as Ebola virus (EBOV) and Marburg virus (MARV), was discovered in Europe. However, since infectious LLOV has never been isolated, th