Zobrazeno 1 - 2
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pro vyhledávání: '"Lyudmila A. Ozolinya"'
Autor:
Marat S. Pavlyukov, L. I. Patrushev, Mikhail I. Shakhparonov, Alina M. Gamisoniya, Ksenia Anufrieva, Ksenia V. Morozova, T. F. Kovalenko, Lyudmila A. Ozolinya, Mikhail Yu. Bobrov, Yulia E. Dobrokhotova
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0243093 (2021)
PLoS ONE, Vol 16, Iss 1, p e0243093 (2021)
The processed pseudogene PTENP1 is involved in the regulation of the expression of the PTEN and acts as a tumor suppressor in many types of malignances. In our previous study we showed that PTENP1 methylation is present not only in tumor, but also in
Publikováno v:
Acta Naturae
The tumor suppressor PTEN controls multiple cellular functions, including cell cycle, apoptosis, senescence, transcription, and mRNA translation of numerous genes. In tumor cells, PTEN is frequently inactivated by genetic mutations and epimutations.