Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Lutz Müller"'
Autor:
Karsten Siems, Aileen Becker, Dominique Böttcher, Lutz Müller-Kuhrt, Uwe T. Bornscheuer, Werner Katzer
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Raspberry ketone is a widely used flavor compound in food and cosmetic industry. Several processes for its biocatalytic production have already been described, but either with the use of genetically modified organisms (GMOs) or incomplete co
Autor:
Lutz Müller, Tatiana G. Zubkova, Holger Stammer, Victor Margitich, Andrew Mehle, Megan Shaw, Aartjan J. W. te Velthuis, David Boltz, Norbert Gmeinwieser, Jens Milde
Publikováno v:
Antimicrobial Agents and Chemotherapy
Infections with respiratory viruses constitute a huge burden on our health and economy. Antivirals against some respiratory viruses are available, but further options are urgently needed. Enisamium iodide (laboratory code FAV00A, trade name Amizon) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a77a641742922bbdf653b34ee215b3
https://doi.org/10.1101/2020.12.23.20247569
https://doi.org/10.1101/2020.12.23.20247569
Autor:
Xinjian Peng, Federico Sala, Thomas Vial, Denisa Bojkova, Lutz Müller, Marco Guerrini, David Boltz, Stefano Elli, Victor Margitich, Aartjan J. W. te Velthuis, Miguel Muzzio, Cesare Cosentino, Andrew Goy, Marco Bechtel, Jindrich Cinatl
Publikováno v:
Biomedicines, Vol 9, Iss 1254, p 1254 (2021)
Biomedicines
Volume 9
Issue 9
Biomedicines
Volume 9
Issue 9
Pandemic SARS-CoV-2 causes a mild to severe respiratory disease called coronavirus disease 2019 (COVID-19). While control of the SARS-CoV-2 spread partly depends on vaccine-induced or naturally acquired protective herd immunity, antiviral strategies
Autor:
Andreas Zeller, Lutz Müller, Christine Schubert, Melanie Guérard, Matthias Festag, Thomas Singer
Publikováno v:
Toxicology and Applied Pharmacology. 279:419-427
The incidence of micronucleated-cells is considered to be a marker of a genotoxic event and can be caused by direct- or indirect-DNA reactive mechanisms. In particular, small increases in the incidence of micronuclei, which are not associated with to
Autor:
Anja Freiwald, Annabell Witzke, Sylvia J. Wowro, Christopher Weidner, Frank C. Schroeder, K. Kawamoto, Karsten Siems, Magdalena Kliem, Sascha Sauer, Lutz Müller-Kuhrt
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma) is an important gene regulator in glucose and lipid metabolism. Unfortunately, PPARgamma-activating drugs of the thiazolidinedione class provoke advers
Autor:
Elmar Gocke, Lutz Müller
Publikováno v:
Mutation Research/Reviews in Mutation Research. 752:67-71
UV is the most abundant human carcinogen, and protection from extensive exposure to it is a widespread human health issue. The use of chemicals (sunscreens) for protection is intuitive and efficacious. However, these chemicals may become activated to
Autor:
Hans Peter Grimm, Yuichiro Sakamoto, Heinrich Bürgin, Akifumi Shioda, Wolfgang F. Richter, Jun Amano, Lutz Müller, Masami Suzuki, Ryo Takai, Yoshinobu Higuchi, Shuichi Chiba, Akinori Kawamura, Takayuki Sakurai
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 98:170-182
Interleukin-6 (IL-6) is involved in the pathogenesis of multiple disorders, including juvenile autoimmune diseases. IL-6 participates in a broad spectrum of physiological events, and the IL-6 receptor (IL-6R) is widely distributed across multiple org
Autor:
Masami Suzuki, Yuichiro Sakamoto, Kana Ishihara, Yoshinobu Higuchi, Shuichi Chiba, Takayuki Sakurai, Lutz Müller, Ryo Takai, Jun Amano, Heinrich Bürgin, Akinori Kawamura, Thomas Singer
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 95:304-317
Possible effects of interleukin-6 (IL-6) on reproductive performance, embryonal development, parturition, and postnatal development have been suggested based on protein/mRNA expression level of IL-6 in related organs, but less is known about function
Autor:
Maria Cristina De Vera Mudry, Alexander Flohr, Thomas Singer, Franziska Regenass-Lechner, Lutz Müller, Helmut Jacobsen, Laurence Ozmen, Matthias Festag, Bernd Altmann
Publikováno v:
International Journal of Alzheimer's Disease
International Journal of Alzheimer's Disease, Vol 2012 (2012)
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Theγ-secretase complex is a promising target in Alzheimer’s disease because of its role in the amyloidogenic processing ofβ-amyloid precursor protein. This enzyme also catalyzes the cleavage of Notch receptor, resulting in the nuclear translocati
Autor:
Lutz Müller, Jan van Benthem, Hans Jörg Martus, Raffaella Corvi, Peter Kasper, David Kirkland, Federica Madia
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 795
In 2008 we published recommendations on chemicals that would be appropriate to evaluate the sensitivity and specificity of new/modified mammalian cell genotoxicity tests, in particular to avoid misleading positive results. In light of new data it is