Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laura Baseler"'
Autor:
Jichao Chen, Nagireddy Putluri, Bingnan Gu, Hunain Alam, Tsai Yu Chen, Chandrashekar R. Ambati, Min Gyu Lee, Florian L. Muller, Chae Young Han, Kunal Rai, Manish Kumar, Shilpa S. Dhar, Yu Hsi Lin, Francesco J. DeMayo, Mayinuer Maitituoheti, Ming Tang, Laura Baseler, Samir B. Amin, Elsa R. Flores
Publikováno v:
Cancer Cell
Epigenetic modifiers frequently harbor loss-of-function mutations in lung cancer, but their tumor-suppressive roles are poorly characterized. Histone methyltransferase KMT2D (a COMPASS-like enzyme, also called MLL4) is among the most highly inactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718310ff05a5d3c871973414ebb0ec8d
https://europepmc.org/articles/PMC7178078/
https://europepmc.org/articles/PMC7178078/
Autor:
Shilpa S. Dhar, Min Gyu Lee, Kaifu Chen, Sarah J. Wu, Laura Baseler, Jie Lv, Elsa R. Flores, Na Li, Hunain Alam
Publikováno v:
Cancer Research. 78:3834-3848
Lung adenocarcinoma is a major form of lung cancer, which is the leading cause of cancer death. Histone methylation reader proteins mediate the effect of histone methylation, a hallmark of epigenetic and transcriptional regulation of gene expression.
Autor:
Bobbie J. Rimel, Guillermina Lozano, Adel K. El-Naggar, Vinod Pant, Swathi Arur, Neeraj K. Aryal, Paul J. Goodfellow, David G. Mutch, Laura Baseler, Amanda R. Wasylishen
Publikováno v:
Cancer Res
Dicer1 functions as a tumor suppressor in mouse models. In humans, somatic mutations are associated with many cancers in adults, and patients with DICER1 syndrome with DICER1 germline mutations are susceptible to childhood cancers. Dicer is phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52290e8576d9fae8cc87209919fdd660
https://europepmc.org/articles/PMC6522273/
https://europepmc.org/articles/PMC6522273/
Autor:
Amanda R. Wasylishen, Neeraj K. Aryal, Adel K. El-Naggar, Awdhesh Kalia, Swathi Arur, Laura Baseler, Bin Liu, Vinod Pant, Jan Parker-Thornburg, Guillermina Lozano
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(3)
DICER1 gene alterations and decreased expression are associated with developmental disorders and diseases in humans. Oscillation of Dicer1 phosphorylation and dephosphorylation regulates its function during the oocyte-to-embryo transition in Caenorha
Autor:
Kunal Rai, Tsai Yu Chen, Ming Tang, Shilpa S. Dhar, Samir B. Amin, Bingnan Gu, Hunain Alam, Florian L. Muller, Francesco J. DeMayo, Yu His Lin, Jichao Chen, Min Gyu Lee, Laura Baseler, Mayinuer Maitituoheti
Epigenetic modifiers often harbor loss-of-function mutations in lung cancer, but their tumor-suppressive roles are poorly characterized. Here we show that lung-specific loss of the gene encoding the histone methyltransferase MLL4 (alias KMT2D; a COMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8809356e4d81562ae69465890c1f0a
Autor:
Yu Chen Lee, Guoyu Yu, Christopher J. Logothetis, Monzur Murshed, Li Yuan Yu-Lee, Laura Baseler, Sue Hwa Lin, Chien Jui Cheng, Keigi Fujiwara, Sankar N. Maity, Jun Ichi Abe, Gary E. Gallick, Nhat Tu Le, Khoi Chu, Song Chang Lin, Xin Zhou, Benoit deCrombrugghe
Prostate cancer (PCa) bone metastasis is frequently associated with bone-forming lesions, but the source of the osteoblastic lesions remains unclear. We show that the tumor-induced bone derives partly from tumor-associated endothelial cells that have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9bc3cbc8f96635fb6cbd087dc4c9ab
https://europepmc.org/articles/PMC5512590/
https://europepmc.org/articles/PMC5512590/
Lack of Correlation Between Papillomaviral DNA in Surgical Margins and Recurrence of Equine Sarcoids
Publikováno v:
Journal of Equine Veterinary Science. 34:722-725
Bovine papillomavirus (BPV) types 1 (BPV-1) and 2 (BPV-2) are causally associated with the development of equine sarcoid tumors. Recurrence rates after surgical excision of sarcoids are estimated to be 30%–40%. We hypothesized that the presence of
Publikováno v:
Annual review of pathology. 12
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging across the vast equatorial belt of the African continent to cause epidemics of highly fatal hemorrhagic fever. The 2013-2015 West African epidemic, by far the m
Publikováno v:
Journal of the American Veterinary Medical Association. 245:501-503
Autor:
Rebecca Rosenke, Emmie de Wit, Darryl Falzarano, Laura Baseler, Dana P. Scott, Vincent J. Munster, Heinz Feldmann, Tina Thomas
Publikováno v:
The American Journal of Pathology
{\textless}p{\textgreater}Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in a human with severe pneumonia in 2012. Since then, infections have been detected in {\textgreater}1500 individuals, with disease severity rangin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6963d0bd46315ded2cc2a95a1a524235
https://zenodo.org/record/3949000
https://zenodo.org/record/3949000