Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kanchan Rao"'
Autor:
Anne Marijn Kramer, Juliana Silva, Rachel Richardson, Andre Lopes, Patrycja Wawrzyniecka, Robert Wynn, Kanchan Rao, Bilyana Popova, Shimobi Onuoha, Gulrukh Ahsan, Paul Veys, Jenny Yeung, Aleks Guvenel, Gary Wright, Giovanna Lucchini, Krystle Villanueva, Mathieu Ferrari, Farzin Farzaneh, Winston Vetharoy, Denise Bonney, Jack Bartram, Fernanda Castro, Leila Mekkaoui, Sara Ghorashian, Joan Casanovas-Company, Somayya Manzoor, Persis Amrolia, Jan Chu, Tony Brooks, Danielle Pinner, Kim Champion, Rachael Hough, Sarah J. Albon, Ajay Vora, Robert Chiesa, Nicholas Goulden, Arina Lazareva, Martin Pule, Kimberly Gilmour, Oana Ciocarlie, Sujith Samarasinghe, Gordon Weng-Kit Cheung, Sarah Inglott, Allan Hackshaw
Publikováno v:
Nature Medicine. 25:1408-1414
Chimeric antigen receptor (CAR)-modified T cells targeting CD19 demonstrate unparalleled responses in relapsed/refractory acute lymphoblastic leukemia (ALL)1–5, but toxicity, including cytokine-release syndrome (CRS) and neurotoxicity, limits broad
Autor:
Timothy Best, John C. Hartley, Sunando Roy, Rachel Williams, Chloe E. Myers, Helen Dunn, Charlotte J. Houldcroft, Charlotte A Williams, Ben Margetts, Cristina Venturini, Kanchan Rao, Kathryn J. Rolfe, José Afonso Guerra-Assunção, Judith Breuer
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
A recent surge in human mastadenovirus (HAdV) cases, including five deaths, amongst a haematopoietic stem cell transplant population led us to use whole genome sequencing (WGS) to investigate. We compared sequences from 37 patients collected over a 2
Autor:
Daniel P. Depledge, Kanchan Rao, John C. Hartley, Joseph F. Standing, Ben Margetts, Rachel Williams, Judith Breuer, Elaine Cloutman-Green, Sunando Roy, Julianne R Brown, Charlotte J. Houldcroft, Sofia Morfopoulou, Erika Yara Romero, Juliana Cudini, Divya Shah
Publikováno v:
The Journal of Infectious Diseases. 218:1261-1271
Background Adenoviruses are significant pathogens for the immunocompromised, arising from primary infection or reinfection. Serotyping is insufficient to support nosocomial transmission investigations. We investigate whether whole-genome sequencing (
Autor:
Siobhan O. Burns, Joop S.E. Laven, Graham Davies, Emma C. Morris, Kanchan Rao, Maite E. Houwing, Marry M. van den Heuvel-Eibrink, Alison D. Leiper, Anne-Lotte F. van der Kooi, Stephen Nussey
Publikováno v:
Bone Marrow Transplantation. 56:521-521
Autor:
Vijay G R Peddareddigari, Liz Clark, Shaun Cordoba, Paul Veys, Kanchan Rao, Robert Wynn, Ajay Vora, Martin Pule, Muhammad Al-Hajj, Persis Amrolia, Rachael Hough, Ekaterini Kotsopoulou, Robert Chiesa, Denise Bonney, Nushmia Z. Khokhar, Shimobi Onuoha
Publikováno v:
Blood. 134:2620-2620
Introduction CAR T-cell therapies directed against CD19 or CD22 have shown remarkable activity in r/r B-ALL but relapse due to target antigen down-regulation/loss has been the major cause of treatment failure. To address this, we developed AUTO3, a C
Autor:
Stuart Adams, Persis Amrolia, Juliana M. Furtado-Silva, Kanchan Rao, Robert Chiesa, Waseem Qasim, Paul Veys, Shahnaz Bibi, Austen Worth, Adrian J. Thrasher, Kimberly Gilmour, Giovanna Lucchini, Reem Elfeky
Publikováno v:
The Journal of allergy and clinical immunology. 142(5)
Autor:
Cristián S. Fahrenkrog, Kanchan Rao, Rachel Hough, Robert Chiesa, Persis Amrolia, Paul Veys, Aurore Saudemont, Prashant Hiwarkar, Catherine M. Cale, Waseem Qasim, Stuart Adams, Austen Worth, Claudia A. Montiel-Equihua, Kimberly Gilmour, Nick Goulden, Hong Zhan, Sophie Derniame
Publikováno v:
British Journal of Haematology. 156:656-666
Umbilical cord blood transplant (UCBT) is associated with impaired early immune reconstitution. This might be explained by a lower T-cell dose infused, the naivety of cord blood T-cells and the use of in vivo T-cell depletion. We studied the pattern
Autor:
Persis Amrolia, Waseem Qasim, Robert Chiesa, Juliana M. Furtado-Silva, Kanchan Rao, Bobby Gaspar, Austen Worth, Paul Veys, Giovanna Lucchini, Reem A. El-Feky
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:2279-2282.e2
Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses
Autor:
Paul Veys, Francesco Dazzi, Olle Ringdén, Lynne M. Ball, Kanchan Rao, Katarina Le Blanc, Sujith Samarasinghe, Arjan C. Lankester, Helen Karlsson, Mehmet Uzunel, Persis Amrolia, Berit Sundberg
Publikováno v:
Blood. 112(3)
Mesenchymal stem cells (MSCs) suppress alloantigen-induced T-cell functions in vitro and infusion of third-party MSCs seems to be a promising therapy for graft-versus-host disease (GVHD). Little is known about the specificity of immunosuppression by
Publikováno v:
Restorative Neurology and Neuroscience. 1:347-360
Fetal mouse retinae transplanted to the mesencephalon of neonatal rats generally survive for prolonged periods of time without immune suppression suggesting that such grafts enjoy a degree of immunological privilege. A small, but consistent percentag