Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Jun Fan"'
Publikováno v:
Journal of Microbiology and Biotechnology. 31:1732-1740
Tobacco etch virus protease (TEVp) is a useful tool for removing fusion tag, but wild type TEVp is less stable under the oxidized redox state. In this work, we introduced and combined C19S, C110S and C130S into the TEVp variant containing T17S, L56V,
Publikováno v:
New Phytologist. 232:1808-1822
Necrosis- and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs) constitute a superfamily of proteins toxic to dicot plants, but the molecular basis of this toxicity remains obscure. Using quantitative trait locus (QTL) analysis we investigated
Autor:
Chen Qu, Yuchuan Jiang, Binkui Li, Mingrong Cao, Wei Huang, Nan Yao, Lu He, Jun Fan, Shuang Peng, Kunpeng Hu, Guo Chen, Wen-Cai Ye, Dong Chen, Jian Hong, Jinying Li, Yunfei Yuan
Publikováno v:
Hepatology. 74:458-473
BACKGROUND AND AIMS Myofibroblasts play a pivotal role in the development and progression of HCC. Here, we aimed to explore the role and mechanism of myofibroblast Musashi RNA binding protein 2 (MSI2) in HCC progression. APPROACH AND RESULTS Myofibro
Publikováno v:
Tumori Journal. 108:12-18
Epidermal growth factor receptor ( EGFR) mutations and anaplastic lymphoma kinase ( ALK) rearrangements are considered mutually exclusive in non-small cell lung cancer (NSCLC), especially in lung adenocarcinoma (LUAC). However, sporadic cases harbori
Autor:
James Denvir, Hasitha Chavva, Boyd R. Rorabaugh, Daniel A. Brazeau, Donald A. Primerano, Jun Fan, Sarah L. Seeley
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
BMC Genomics
BMC Genomics
Background Prior work demonstrated that female rats (but not their male littermates) exposed to methamphetamine become hypersensitive to myocardial ischemic injury. Importantly, this sex-dependent effect persists following 30 days of subsequent absti
Autor:
Ying Liu, Xiao-Ya Ren, Ya-Guang Peng, Shao-Ke Chen, Xin-Ran Cheng, Miao Qin, Xiao-Ling Wang, Yan-Ning Song, Li-Jun Fan, Chun-Xiu Gong, Li-Shao Guo.
Publikováno v:
Chinese Medical Journal
Chinese Medical Journal, Vol 134, Iss 10, Pp 1152-1159 (2021)
Chinese Medical Journal, Vol 134, Iss 10, Pp 1152-1159 (2021)
Background:. Compared to adult studies, studies which involve the treatment of pediatric congenital hypogonadotropic hypogonadism (CHH) are limited and no universal treatment regimen is available. The aim of this study was to evaluate the feasibility
Autor:
Xiao Xiong, Shegan Gao, Zhimeng Yao, Jianlin Zhu, Jun Fan, Yi Guo, Wan Lin, Hao Zhang, Kai Li, Yan Chen, Fuyou Zhou, Yunlong Pan, Lu Wang, Yusheng Lin, Yuping Chen, Xiaozheng Xu, Sai Ching J. Yeung
Publikováno v:
Cancer letters, 501, 1-11. ELSEVIER IRELAND LTD
Transcription-induced chimeric RNAs are an emerging area of research into molecular signatures for disease biomarker and therapeutic target development. Despite their importance, little is known for chimeric RNAs-relevant roles and the underlying mec
Publikováno v:
Chemical Research in Toxicology. 34:70-79
Diclofenac sodium (DFS), a nonsteroidal anti-inflammatory drug, is frequently used in ophthalmology, but it causes negative effects on corneas. The mechanisms underlying the toxicities to corneas remains unclear. The present study was designed to ass
Autor:
Yiming Sun, Meng-di Dai, Yueliang Wang, Yang Dai, Xia Peng, Jun Fan, Yuming Wang, Wenhu Duan, Lan-lan Li, Jing Ai, Jian Ding, Yinchun Ji
Publikováno v:
Acta Pharmacol Sin
Fibroblast growth factor receptor (FGFR) is a promising anticancer target. Currently, most FGFR inhibitors lack sufficient selectivity and have nonnegligible activity against kinase insert domain receptor (KDR), limiting their feasibility due to the
Publikováno v:
J Thorac Dis
BACKGROUND: Differentiating synchronous double primary lung adenocarcinoma (SDPLA) from interpulmonary metastasis (IPM) has significant therapeutic and prognostic implications. This retrospective study aimed to investigate the potential of computed t