Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jia, Tong"'
Autor:
Kong-Peng Lam, Joey Kay Hui Teo, Susana Soo-Yeon Kim, Hsueh Lee Lim, Alison P. Lee, Andy Hee-Meng Tan, Jia Tong Loh, Koon-Guan Lee
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
How pathogenesis of inflammatory bowel disease (IBD) depends on the complex interplay of host genetics, microbiome and the immune system is not fully understood. Here, we showed that Downstream of Kinase 3 (DOK3), an adapter protein involved in immun
Autor:
Yan Liu, Yong-Qiang Zhou, Wei Guan, Adnan Mohammed Algradi, Dan-Dan Wu, Zi-Tang Qi, Jia-Tong Wu, Juan Pan, Bing-You Yang, Hai-Xue Kuang
Publikováno v:
Journal of Asian Natural Products Research. 24:884-890
A new ent-kaurane diterpenoid, named kaurane daturoside A (1), was isolated from the 70%-EtOH extract of dried pericarps of Datura metel L., along with six known terpenoids, 16α,17-dihydroxy-ent-kauran-19-diglycoside (2), cyclosieversioside F (3), a
Autor:
Jiqiong Zhou, Youzhi Zhang, Lin Liu, Wei Liu, Guangyan Feng, Feng Huahao, Cheng Bizhen, Gang Nie, Xiao Ma, Hou Jieru, Muhammad Zafar Iqbal, Zhou Li, Yan Peng, Jia Tong
Publikováno v:
Plant Physiology and Biochemistry. 165:147-160
S-adenosylmethionine decarboxylase (SAMDC) mediates the biosynthesis of polyamines (PAs) and plays a positive role in plants’ response to adversity stress tolerance. In this study, we isolated a SAMDC gene from white clover, which is located in mit
Autor:
Jingyi Li, Yuxia Zhang, Gen Lu, Tak Wah Mak, Sze Wai Ng, Kong-Peng Lam, Meng Zhao, Zhong Huang, Andy Hee-Meng Tan, Xiang Lin, Xiaohui Liu, Zihan Zheng, Kin-Hang Kok, Liwei Lu, Kwok-Yung Yuen, Qian Chen, Jia Tong Loh, Bingtai Lu, Jun Wang, Wanli Liu, King-Hung Ko, Fan Xiao, Xiaohui Wang, Enyu Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Innate immunity is important for host defense by eliciting rapid anti-viral responses and bridging adaptive immunity. Here, we show that endogenous lipids released from virus-infected host cells activate lung γδ T cells to produce interleukin 17 A
Autor:
Jia-Tong Xu, Pei-Yi Xu, Ying Zhou, Hsi-Yuan Huang, Xin-Yi Chen, Si-Yuan Ding, Yi-Gang Chen, Yun Tang, Hsien Da Huang, Si-yao Hu, Meng-Fan Luo, Xin Li, Hsiao Chin Hong, Hua-Li Zuo, Chen-Nan Jin, Yi-Xian Huang, Yue-Yang Xie, Yang-Chi-Dung Lin, Zhe-Yuan Zhou, Jing Li, Le-Shan Zhao
Publikováno v:
Nucleic Acids Research
DNA methylation is an important epigenetic regulator in gene expression and has several roles in cancer and disease progression. MethHC version 2.0 (MethHC 2.0) is an integrated and web-based resource focusing on the aberrant methylomes of human dise
Autor:
Juwon Son, Wen Ying Cui, Changyoon Baek, Junhong Min, Jia Tong Kang, Hyun Jin Yoo, Yun Guang Li
Publikováno v:
Analytical and bioanalytical chemistry. 414(1)
It is challenging to employ nucleic acid-based diagnostics for the in situ detection of Clostridium difficile from complex fecal samples because essential sample preparation and amplification procedures require various experimental resources. In this
Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy
Autor:
Rufang Xiang, Chao Wu, Hua Yan, Zilu Zhang, Ying-Li Wu, Chengning Ma, Junmin Li, Wenbin Xu, Fenghuang Zhan, Jia Tong, Jia Liu, Xiaoguang Xu
Publikováno v:
Haematologica
Multiple myeloma is a malignant plasma-cell disease, which is highly dependent on the hypoxic bone marrow microenvironment. However, the underlying mechanisms of hypoxia contributing to myeloma genesis are not fully understood. Here, we show that lon
Publikováno v:
Plant Disease. 106:1525
Scarlet Beebalm (Monarda didyma) is a perennial ornamental flowering plant in the mint family, Labiatae. Due to low-maintenance, and a long blooming period, it is commonly cultivated in gardens as ...
Autor:
Michael Poidinger, Baptiste Janela, Kyoko Ikumi, Takuma Matoba, Sayuri Yamazaki, Merry Gunawan, Akimichi Morita, I-hsin Su, Tatsuya Toyama, Florent Ginhoux, Lai Guan Ng, Maegan Bunjamin, Jia Tong Loh, Thomas Jun Feng Lim, Kong-Peng Lam
Publikováno v:
iScience, Vol 10, Iss, Pp 23-39 (2018)
iScience
iScience
Summary Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive. Here we demonstrate that Ezh2 controls cutaneous tolerance by regulating Langerhans cell (LC)
Autor:
Chun Wu, Chun-Yuen Wong, Tian-Shu Kang, Jia-Tong Zhang, Chung-Hang Leung, Dik-Lung Ma, Chung-Nga Ko
Publikováno v:
Inorganic Chemistry. 57:14023-14026
We describe in this study a rhodium(III) complex 1 as a new JMJD3 inhibitor and proinflammatory mediator. Complex 1 selectively inhibited the demethylation of H3K27me3 over other similar substrates, indicating its selectivity for JMJD3 over other his