Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Hingorani A"'
Autor:
Vijay P. Bhatt, Aboli Girme, Lal Hingorani, Ishita A. Basera, Ganesh Saste, Sandeep Pawar, Mamta B. Shah
Publikováno v:
Acta Chromatographica. 34:412-421
A validated UHPLC-PDA with an ESI-MS/MS method has been developed for simultaneous estimation of six bioactive alkaloids (magnoflorine, berbamine, columbamine, jatrorrhizine, palmatine and berberine) in the different extracts of the roots of Berberis
Autor:
Erin Oerton, Maik Pietzner, Nicholas J. Wareham, Steve A. Williams, Julia Carrasco-Zanini, Nicola D. Kerrison, Eleanor Wheeler, Aroon D. Hingorani, Claudia Langenberg, Mine Koprulu, Jian'an Luan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Affinity-based proteomics has enabled scalable quantification of thousands of protein targets in blood enhancing biomarker discovery, understanding of disease mechanisms, and genetic evaluation of drug targets in humans through protein quantitative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04e9d019dcc0cf8667744357b8a3cbf
https://www.repository.cam.ac.uk/handle/1810/331034
https://www.repository.cam.ac.uk/handle/1810/331034
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 12, Iss 4, Pp 623-632 (2021)
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine
Background Aging leads to loss of skeletal muscle, diminished muscle strength, and decline in physical functions. Objective This study evaluates Withania somnifera and some dietary interventions to combat muscle weakness in aging rats. Materials and
Autor:
Hannah Sanford-Crane, Jennifer M. Finan, Mark W. Berry, Sohinee Bhattacharyya, Wesley Horton, Erin Helms, Christopher C. DuFort, Chet Oon, Zheng Xia, Rosemary Makar, R. Crystal Chaw, Ariana Sattler, David W. Dawson, Mara H. Sherman, Duanchen Sun, M. Kathrina Onate, Sunil R. Hingorani
Publikováno v:
Cancer Discovery. 12:484-501
Cancer-associated fibroblast (CAF) heterogeneity is increasingly appreciated, but the origins and functions of distinct CAF subtypes remain poorly understood. The abundant and transcriptionally diverse CAF population in pancreatic ductal adenocarcino
Autor:
Eric R. Gamazon, Erin Oerton, Nicola D. Kerrison, Nicholas J. Wareham, Aroon D. Hingorani, Maik Pietzner, Juan P Casas, Chris Finan, Rachel Ostroff, Gabi Kastenmüller, Steve A. Williams, Johannes Raffler, Eleanor Wheeler, Julia Carrasco-Zanini, Jian'an Luan, Markus Ralser, Victoria P W Auyeung, Claudia Langenberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nat. Commun. 11:6397 (2020)
Nature Communications
Nat. Commun. 11:6397 (2020)
Nature Communications
Funder: Medical Research Council
Understanding the genetic architecture of host proteins interacting with SARS-CoV-2 or mediating the maladaptive host response to COVID-19 can help to identify new or repurpose existing drugs targeting those prot
Understanding the genetic architecture of host proteins interacting with SARS-CoV-2 or mediating the maladaptive host response to COVID-19 can help to identify new or repurpose existing drugs targeting those prot
Autor:
Sandeep Pawar, Amit Mirgal, Sonali S. Bharate, Aboli Girme, Saurabh Patel, Ganesh Saste, D. Srinivasa Reddy, Anshuly Tiwari, Sautik Ghoshal, Lal Hingorani, Chetana Ghule, Ram A. Vishwakarma, Sandip B. Bharate
Publikováno v:
ACS Omega, Vol 6, Iss 36, Pp 23460-23474 (2021)
Food ingredients hold a higher nutritional value as a botanical supplement playing a vital role in modifying and maintaining the physiological conditions that improve human health benefits. The Kashmir saffron (Crocus sativus L; KCS) obtained from dr
Publikováno v:
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine, Vol 12, Iss 3, Pp 506-513 (2021)
Journal of Ayurveda and Integrative Medicine, Vol 12, Iss 3, Pp 506-513 (2021)
Background Nishamalaki is an Ayurvedic herbal formulation used to treat type 2 diabetes mellitus (T2DM), comprises Emblica officinalis and Curcuma longa. Objective(s) One of the main cause of T2DM is Insulin Resistance (IR) hence, this study was plan
Publikováno v:
JPC – Journal of Planar Chromatography – Modern TLC
The objective of the present work was to develop a simple, specific, and fast high-performance thin-layer chromatographic (HPTLC) method to identify and quantify cordifolioside A, 20-β-hydroxyecdysone and columbin with HPTLC‒electrospray ionizatio
Autor:
Gregory Gatto, Wendong Zhang, Douglas J. Harrison, Yifei Wang, Edward A. Kolb, Richard Gorlick, Stephen W. Erickson, Michael Roth, Jonathan Gill, Malcolm A. Smith, Beverly A. Teicher, Pooja Hingorani
Publikováno v:
Mol Cancer Ther
Membrane protein leucine–rich repeat containing 15 (LRRC15) is known to be expressed in several solid tumors including osteosarcoma. ABBV-085, an antibody–drug conjugate against LRRC15, conjugated to monomethyl auristatin E (MMAE), was studied in
APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis
Autor:
John F. O’Toole, Katherine R. Tuttle, Kevin V. Lemley, Matthew G. Sampson, Marie C. Hogan, Jarcy Zee, Michelle T McNulty, Sharon G. Adler, Vimal K. Derebail, Chia-shi Wang, Raed Bou Matar, Elizabeth J. Brown, Katherine MacRae Dell, Fernando C. Fervenza, Keisha L. Gibson, Gerald B. Appel, Cynthia C. Nast, Ambarish M. Athavale, Pamela Singer, Jonathan Ashley Jefferson, Richard A. Lafayette, Jeffrey B. Kopp, Larry A. Greenbaum, Kevin E.C. Meyers, Laura Barisoni, Alessia Fornoni, Jiten Patel, Kamalanathan K. Sambandam, Crystal A. Gadegbeku, Meredith A. Atkinson, Serena M. Bagnasco, Matthias Kretzler, Jonathan J. Hogan, Heather N. Reich, Suzanne Vento, Howard Trachtman, Jen Jar Lin, Jeffrey B. Hodgin, Lawrence B. Holzman, Tarak Srivastava, Sangeeta Hingorani, Frederick J. Kaskel, Michelle Hladunewich, Olga Zhdanova, Christine B. Sethna, Dhruti P. Chen, Debbie S. Gipson, John C. Lieske
Publikováno v:
Pediatr Nephrol
Background: The G1 and G2 alleles of apolipoprotein L1 (APOL1) are common in the Black population and associated with increased risk of focal segmental glomerulosclerosis (FSGS). The molecular mechanisms linking APOL1 risk variants with FSGS are not