Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Heinrich Roder"'
Autor:
Heinrich Roder, Carlos R. Oliveira, Joanna Roder, Senait Asmellash, Julia Grigorieva, Lelia Net
Publikováno v:
Clinical Mass Spectrometry. 15:44-53
Mass spectral data from multiple samples are suitable for a hypothesis-free development of clinically useful multivariate tests using modern machine learning techniques. However, the transition from discovery to adoption of proteomic tests has proved
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Differential scanning fluorimetry (DSF), also known as ThermoFluor or Thermal Shift Assay, has become a commonly-used approach for detecting protein-ligand interactions, particularly in the context of fragment screening. Upon binding to a folded prot
Autor:
Isabel Cuesta, Makiko Iwafuchi, Pilar Santisteban, Kenneth S. Zaret, Naomi Takenaka, Greg Donahue, Heinrich Roder, Steven H. Seeholzer, Anna B. Osipovich, Mark A. Magnuson
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature genetics
instname
Nature genetics
Gene network transitions in embryos and other fate-changing contexts involve combinations of transcription factors. A subset of fate-changing transcription factors act as pioneers; they scan and target nucleosomal DNA and initiate cooperative events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176400aba75e757968d50b0ee0eeeca3
http://hdl.handle.net/10261/222177
http://hdl.handle.net/10261/222177
Publikováno v:
Protein Science. 22:1336-1348
The development of tertiary structure during folding of staphylococcal nuclease (SNase) was studied by time-resolved fluorescence resonance energy transfer measured using continuous- and stopped-flow techniques. Variants of this two-domain protein co
Publikováno v:
ResearcherID
Unfolded apocytochrome c acquires an alpha-helical conformation upon interaction with lipid. Folding kinetic results below and above the lipid's CMC, together with energy transfer measurements of lipid bound states, and salt-induced compact states in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7c7eb0bfc4858881475df9da958011
https://doi.org/10.1110/ps.8.2.381
https://doi.org/10.1110/ps.8.2.381
Autor:
Richard M. Caprioli, Joanna Roder, Erin H. Seeley, Julia Grigorieva, MEric Gershwin, Heinrich Roder, Christopher L. Bowlus
Publikováno v:
Cellular & Molecular Immunology. 8:237-242
Primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are the major forms of autoimmune liver diseases each characterized by the destruction of a specific liver cell type and the presence of differing au
Publikováno v:
Virology. 407(2):333-340
The 195 amino acid basic protein (δAg) of hepatitis delta virus (HDV) is essential for replication of the HDV RNA genome. Numerous properties have been mapped to full-length δAg and attempts made to link these to secondary, tertiary and quaternary
Autor:
Julie R. Brahmer, Adriana Gonzalez, Joan H. Schiller, Heinrich Roder, Ju Whei Lee, Joseph M. Amann, David P. Carbone
Publikováno v:
Journal of Thoracic Oncology. 5(2):169-178
Introduction Serum proteomics and mutations in the epidermal growth factor receptor ( EGFR ) and KRAS have been associated with benefit after therapy with EGFR-targeted therapies in non-small cell lung cancer, but all three have not been evaluated in
Publikováno v:
Protein Science. 11:82-91
Pulsed hydrogen exchange methods were used to follow the formation of structure during the refolding of acid-denatured staphylococcal nuclease containing a stabilizing Leu substitution at position 124 (H124L SNase). The protection of more than 60 bac
Publikováno v:
Journal of Molecular Biology. 383:437-453
Despite close structural similarity, the ferric and ferrous forms of cytochrome c differ greatly in terms of their ligand binding properties, stability, folding, and dynamics. The reduced heme iron binds diatomic ligands such as CO only under destabi