Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Hansell A"'
Autor:
Michelle L Le Brocq, John Dm Campbell, Gerard J. Graham, Rachel S Cooper, Christopher A.H. Hansell, Paul Burgoyne, Alan J. Hayes
Publikováno v:
Journal of Leukocyte Biology. 111:1243-1251
Dendritic cell therapy has been a promising addition to the current armory of therapeutic options in cancer for more than 20 years but has not yet achieved breakthrough success. To successfully initiate immunity, dendritic cells have to enter the lym
Autor:
Hans Richter, Mitchell C. Lock, Gina L. J. Galli, Olga V. Patey, Eduardo Villamor, Emilio A. Herrera, Dino A. Giussani, Andrew W. Trafford, Jeremy A. Hansell, Emily J. Camm, Carlos E. Blanco
Publikováno v:
Hansell, J A, Richter, H G, Camm, E J, Herrera, E A, Blanco, C E, Villamor, E, Patey, O V, Lock, M C, Trafford, A W, Galli, G L J & Giussani, D A 2022, ' Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy ', Journal of Pineal Research, vol. 72, no. 1, e12766 . https://doi.org/10.1111/jpi.12766
Journal of Pineal Research, 72(1):e12766. Wiley-Blackwell
Journal of Pineal Research, 72(1):e12766. Wiley-Blackwell
Funder: British Heart Foundation; Id: http://dx.doi.org/10.13039/501100000274
Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal
Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b6e50f8550d087295176e17ef513e5
https://hdl.handle.net/11541.2/29472
https://hdl.handle.net/11541.2/29472
Autor:
Gerard J. Graham, Megan K. L. MacLeod, Gillian J. Wilson, Samantha Love, Christopher A.H. Hansell, Marieke Pingen
Publikováno v:
European Journal of Immunology
Analysis of chemokine receptor, and atypical chemokine receptor, expression is frequently hampered by the lack of availability of high‐quality antibodies and the species specificity of those that are available. We have previously described methodol
Autor:
Kathleen J. Propert, Xiangping Lu, Margaret E Choi, Frederick J. Balzer, Shira T. Rosenblum, Daniel J VanBelzen, Leonard T. Su, Peter P. Nghiem, Joe N. Kornegay, Marilyn A. Mitchell, Mihail Petrov, Shangzhen Zhou, Benjamin W. Kozyak, Christopher D. Greer, Alock Malik, Yafeng Song, Andrew F. Mead, Ranjith K Krishnankutty, Robert A. French, Hansell H. Stedman, Emanuele Loro, Leon Morales, Tejvir S. Khurana
Publikováno v:
Nature Medicine. 25:1505-1511
The essential product of the Duchenne muscular dystrophy (DMD) gene is dystrophin1, a rod-like protein2 that protects striated myocytes from contraction-induced injury3,4. Dystrophin-related protein (or utrophin) retains most of the structural and pr
Autor:
Paul M. Thompson, Brendan P. Zietsch, Greig I. de Zubicaray, Lachlan T. Strike, Katie L. McMahon, Margaret J. Wright, Narelle K. Hansell
Publikováno v:
Brain Structure and Function. 224:2805-2821
Comparing estimates of the amount of genetic and environmental variance for different brain structures may elucidate differences in the genetic architecture or developmental constraints of individual brain structures. However, most studies compare es
Publikováno v:
Sci Total Environ
Fungal spores make up a significant proportion of organic matter within the air. Allergic sensitisation to fungi is associated with conditions including allergic fungal airway disease. This systematic review analyses outdoor fungal spore seasonality
Autor:
Jean Bennett, Kendall A. Lundgreen, Elisia D. Tichy, Shangzhen Zhou, Christopher D. Greer, Chomistek Sj, Leon Morales, Hansell H. Stedman, Carpenter Lj, Albert M. Maguire, Bailey Rj, Hoffman Jg, Gordon Gs, Bridges Cr, Kasden Cm, Jorge E. Osorio, Philip Hicks, Tabin Gc, Luo A, Benjamin W. Kozyak, Paul Bates, Salas-Quinchucua C
Prevention of COVID-19 is widely believed to depend on neutralization of SARS-CoV-2 by vaccine-induced humoral immunity1,2, raising concern that emerging escape variants may perpetuate the pandemic3–6. Here we show that a single intramuscular injec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0480011884baf2b9a13556cf4b8701b8
https://doi.org/10.1101/2021.08.16.456441
https://doi.org/10.1101/2021.08.16.456441
Autor:
Anna Hansell, Chen J, Nick Shrine, Tobin, Louise V. Wain, Erzurumluoglu Am, Carl A. Melbourne
Impaired lung function is predictive of mortality and is a key component in the diagnosis of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4deda36f062fd5d990b6b1eddcf575a
https://doi.org/10.1101/2021.06.03.21256376
https://doi.org/10.1101/2021.06.03.21256376
Autor:
Mike Hansell, Maggie Reilly, Susan D. Healy, Sophie C Edwards, Shoko Sugasawa, Rowan Stanforth, Emily Bruton
Funding: Japan Society for the Promotion of Science (Grant Number(s): H28/1018); Biotechnology and Biological Sciences Research Council (Grant Number(s): BB/S01019X/1, EASTBIO scholarship). The materials that birds use to build their nests have a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738f59fb240b7566095c5ab345f0fc67
https://hdl.handle.net/10023/23124
https://hdl.handle.net/10023/23124
Autor:
Phuwanat Sakornsakolpat, James F. Wilson, María Soler Artigas, Beate Stubbe, Nicholas J. Wareham, James D. Crapo, Victoria E. Jackson, Eleftheria Zeggini, Olga G. Troyanskaya, Medea Imboden, A. Mesut Erzurumluoglu, Adam S. Butterworth, Carl A. Melbourne, Ian Sayers, Lars Lind, Stefan Weiss, Margaret M. Parker, Timmers Prhj, Edwin K. Silverman, John C. Whittaker, Ian P. Hall, Ozren Polasek, Mika Kähönen, Katherine A. Fawcett, Anna Hansell, Liming Li, David J. Porteous, Louise V. Wain, Robert A. Scott, Richard Packer, Richard J. Allen, Robin G Walters, Anna L. Guyatt, Terho Lehtimäki, Nicole Probst-Hensch, Shona M. Kerr, Christian Gieger, Matthias Wielscher, Rajesh Rawal, Jing Hua Zhao, John E. Hokanson, Holger Schulz, Nicola F. Reeve, Claudia Langenberg, Ke Hao, Corry-Anke Brandsma, Megan L. Paynton, Vitart, Dmitry Prokopenko, Jennie Hui, Eugene R. Bleecker, Ma'en Obeidat, John Danesh, Ralf Ewert, Benjamin B. Sun, Frank Dudbridge, Jian Zhou, Brian D. Hobbs, Blair H. Smith, Don D. Sin, Dawn L. DeMeo, Joseph C. Maranville, Ida Surakka, Alison Catherine Murray, Nicholas Locantore, Katherine A. Kentistou, Terri H. Beaty, Igor Rudan, Kuang Lin, Amund Gulsvik, Ian J. Deary, Ruth Tal-Singer, Kijoung Song, David C. Nickle, Michael H. Cho, Jian'an Luan, Joshua D. Hoffman, Georg Homuth, Zhengming Chen, Dandi Qiao, Heiko Runz, Per Bakke, Chiara Batini, Caroline Hayward, Stefan Karrasch, Alan James, Andrew P. Morris, Prescott G. Woodruff, Laura M Yerges Armstrong, David Sparrow, Ulf Gyllensten, James P. Cook, Jonathan Marten, Olli T. Raitakari, Nick Shrine, Deborah A. Meyers, Tobin, Ruth Boxall, Marjo-Riitta Järvelin, David P. Strachan, Sarah E. Harris, Philippe Joubert, Stefan Enroth, Xingnan Li, van den Berge M, Anubha Mahajan, Yohan Bossé, Peter K. Joshi
Publikováno v:
Nature genetics
Nat. Genet. 51, 481-493 (2019)
Shrine, N R G, Guyatt, A, Erzurumluoglu, A M, Jackson, V E, Hobbs, B D, Melbourne, C, Batini, C, Fawcett, K A, Song, K, Sakornsakolpat, P, Li, X, Boxall, R, Reeve, N F, Obeidat, M, Zhao, J H, Wielscher, M, Weiss, S, Kentistou, K, Cook, J P, Sun, B B, Zhou, J, Hui, J, Karrasch, S, Imboden, M, Harris, S, Marten, J, Enroth, S, Kerr, S, Surakka, I, Vitart, V, Lehtimäki, T, Allen, R J, Bakke, P S, Beaty, T H, Bleecker, E R, Bossé, Y, Brandsma, C-A, Chen, Z, Crapo, J D, Danesh, J, Demeo, D L, Dudbridge, F, Ewert, R, Gieger, C, Gulsvik, A, Hansell, A L, Hao, K, Hoffman, J D, Hokanson, J E, Homuth, G, Joshi, P, Joubert, P, Langenberg, C, Li, X, Li, L, Lin, K, Lind, L, Locantore, N, Luan, J, Mahajan, A, Maranville, J C, Murray, A, Nickle, D C, Packer, R, Parker, M M, Paynton, M L, Porteous, D, Prokopenko, D, Qiao, D, Rawal, R, Runz, H, Sayers, I, Sin, D D, Smith, B H, Soler Artigas, M, Sparrow, D, Tal-Singer, R, Timmers, P RHJ, van den Berge, M, Woodruff, P G, Yerges-Armstrong, L M, Troyanskaya, O G, Raitakar, O, Kähönen, M, Polasek, O, Rudan, I, Deary, I, Probst-Hensch, N M, Schulz, H, James, A L, Wilson, J F, Stubbe, B, Zeggini, E, Jarvelin, M-R, Wareham, N, Silverman, E K, Hayward, C, Morris, A P, Butterworth, A S, Scott, R A, Walters, R G, Meyers, D A, Cho, M H, Strachan, D P, Hall, I P & Tobin, M D & Wain, L V 2019, ' New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, pp. 481–493 . https://doi.org/10.1038/s41588-018-0321-7
NATURE GENETICS
Understanding Society Scientific Group 2019, ' New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, no. 3, pp. 481-493 . https://doi.org/10.1038/s41588-018-0321-7
Nature Genetics, 51(3), 481-493. Nature Publishing Group
Nat. Genet. 51, 481-493 (2019)
Shrine, N R G, Guyatt, A, Erzurumluoglu, A M, Jackson, V E, Hobbs, B D, Melbourne, C, Batini, C, Fawcett, K A, Song, K, Sakornsakolpat, P, Li, X, Boxall, R, Reeve, N F, Obeidat, M, Zhao, J H, Wielscher, M, Weiss, S, Kentistou, K, Cook, J P, Sun, B B, Zhou, J, Hui, J, Karrasch, S, Imboden, M, Harris, S, Marten, J, Enroth, S, Kerr, S, Surakka, I, Vitart, V, Lehtimäki, T, Allen, R J, Bakke, P S, Beaty, T H, Bleecker, E R, Bossé, Y, Brandsma, C-A, Chen, Z, Crapo, J D, Danesh, J, Demeo, D L, Dudbridge, F, Ewert, R, Gieger, C, Gulsvik, A, Hansell, A L, Hao, K, Hoffman, J D, Hokanson, J E, Homuth, G, Joshi, P, Joubert, P, Langenberg, C, Li, X, Li, L, Lin, K, Lind, L, Locantore, N, Luan, J, Mahajan, A, Maranville, J C, Murray, A, Nickle, D C, Packer, R, Parker, M M, Paynton, M L, Porteous, D, Prokopenko, D, Qiao, D, Rawal, R, Runz, H, Sayers, I, Sin, D D, Smith, B H, Soler Artigas, M, Sparrow, D, Tal-Singer, R, Timmers, P RHJ, van den Berge, M, Woodruff, P G, Yerges-Armstrong, L M, Troyanskaya, O G, Raitakar, O, Kähönen, M, Polasek, O, Rudan, I, Deary, I, Probst-Hensch, N M, Schulz, H, James, A L, Wilson, J F, Stubbe, B, Zeggini, E, Jarvelin, M-R, Wareham, N, Silverman, E K, Hayward, C, Morris, A P, Butterworth, A S, Scott, R A, Walters, R G, Meyers, D A, Cho, M H, Strachan, D P, Hall, I P & Tobin, M D & Wain, L V 2019, ' New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, pp. 481–493 . https://doi.org/10.1038/s41588-018-0321-7
NATURE GENETICS
Understanding Society Scientific Group 2019, ' New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, no. 3, pp. 481-493 . https://doi.org/10.1038/s41588-018-0321-7
Nature Genetics, 51(3), 481-493. Nature Publishing Group
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we define 279 lung function signals, 139 of which ar