Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gräßler J"'
Autor:
Winkler, T, Day, F, Croteau Chonka, D, Wood, A, Locke, A, Mägi, R, Ferreira, T, Fall, T, Graff, M, Justice, A, Luan, J, Gustafsson, S, Randall, J, Vedantam, S, Workalemahu, T, Kilpeläinen, T, Scherag, A, Esko, T, Kutalik, Z, Heid, I, Loos, R, Abecasis GR, Absher D, Alavere H, Albrecht E, Allen HL, Almgren P, Amin N, Amouyel P, Anderson D, Arnold AM, Arveiler D, Aspelund T, Asselbergs FW, Assimes TL, Atalay M, Attwood AP, Atwood LD, Bakker SJ, Balkau B, Balmforth AJ, Barlassina C, Barroso I, Basart H, Bauer S, Beckmann JS, Beilby JP, Bennett AJ, Ben Shlomo Y, Bergman RN, Bergmann S, Berndt SI, Biffar R, Di Blasio AM, Boehm BO, Boehnke M, Boeing H, Boerwinkle E, Bolton JL, Bonnefond A, Bonnycastle LL, Boomsma DI, Borecki IB, Bornstein SR, Bouatia Naji N, Boucher G, Bragg Gresham JL, BRAMBILLA, PAOLO, Bruinenberg M, Buchanan TA, Buechler C, Cadby G, Campbell H, Caulfield MJ, Cavalcanti Proença C, CESANA, GIANCARLO, Chanock SJ, Chasman DI, Chen YD, Chines PS, Clegg DJ, Coin L, Collins FS, Connell JM, Cookson W, Cooper MN, Croteau Chonka DC, Cupples LA, Cusi D, Day FR, Day IN, Dedoussis GV, Dei M, Deloukas P, Dermitzakis ET, Dimas AS, Dimitriou M, Dixon AL, Dörr M, van Duijn CM, Ebrahim S, Edkins S, Eiriksdottir G, Eisinger K, Eklund N, Elliott P, Erbel R, Erdmann J, Erdos MR, Eriksson JG, Esko T, Estrada K, Evans DM, de Faire U, Fall T, Farrall M, Feitosa MF, Ferrario MM, Ferreira T, Ferrières J, Fischer K, Fisher E, Fowkes G, Fox CS, Franke L, Franks PW, Fraser RM, Frau F, Frayling T, Freimer NB, Froguel P, Fu M, Gaget S, Ganna A, Gejman PV, Gentilini D, Geus EJ, Gieger C, Gigante B, Gjesing AP, Glazer NL, Goddard ME, Goel A, Grallert H, Gräßler J, Grönberg H, Groop LC, Groves CJ, Gudnason V, Guiducci C, Gustafsson S, Gyllensten U, Hall AS, Hall P, Hallmans G, Hamsten A, Hansen T, Haritunians T, Harris TB, van der Harst P, Hartikainen AL, Hassanali N, Hattersley AT, Havulinna AS, Hayward C, Heard Costa NL, Heath AC, Hebebrand J, Heid IM, den Heijer M, Hengstenberg C, Herzig KH, Hicks AA, Hingorani A, Hinney A, Hirschhorn JN, Hofman A, Holmes CC, Homuth G, Hottenga JJ, Hovingh KG, Hu FB, Hu YJ, Huffman JE, Hui J, Huikuri H, Humphries SE, Hung J, Hunt SE, Hunter D, Hveem K, Hyppönen E, Igl W, Illig T, Ingelsson E, Iribarren C, Isomaa B, Jackson AU, Jacobs KB, James AL, Jansson JO, Jarick I, Jarvelin MR, Jöckel KH, Johansson Å, Johnson T, Jolley J, Jørgensen T, Jousilahti P, Jula A, Justice AE, Kaakinen M, Kähönen M, Kajantie E, Kanoni S, Kao WH, Kaplan LM, Kaplan RC, Kaprio J, Kapur K, Karpe F, Kathiresan S, Kee F, Keinanen Kiukaanniemi SM, Ketkar S, Kettunen J, Khaw KT, Kiemeney LA, Kilpeläinen TO, Kinnunen L, Kivimaki M, Kivmaki M, Van der Klauw MM, Kleber ME, Knowles JW, Koenig W, Kolcic I, Kolovou G, König IR, Koskinen S, Kovacs P, Kraft P, Kraja AT, Kristiansson K, KrjutÅjkov K, Kroemer HK, Krohn JP, Krzelj V, Kuh D, Kulzer JR, Kumari M, Kutalik Z, Kuulasmaa K, Kuusisto J, Kvaloy K, Laakso M, Laitinen JH, Lakka TA, Lamina C, Langenberg C, Lantieri O, Lathrop GM, Launer LJ, Lawlor DA, Lawrence RW, Leach IM, Lecoeur C, Lee SH, Lehtimäki T, Leitzmann MF, Lettre G, Levinson DF, Li G, Li S, Liang L, Lin DY, Lind L, Lindgren CM, Lindström J, Liu J, Liuzzi A, Locke AE, Lokki ML, Loley C, Loos RJ, Lorentzon M, Luan J, Luben RN, Ludwig B, Madden PA, Mägi R, Magnusson PK, Mangino M, Manunta P, Marek D, Marre M, Martin NG, März W, Maschio A, Mathieson I, McArdle WL, McCaroll SA, McCarthy A, McCarthy MI, McKnight B, Medina Gomez C, Medland SE, Meitinger T, Metspalu A, van Meurs JB, Meyre D, Midthjell K, Mihailov E, Milani L, Min JL, Moebus S, Moffatt MF, Mohlke KL, Molony C, Monda KL, Montgomery GW, Mooser V, Morken MA, Morris AD, Morris AP, Mühleisen TW, Müller Nurasyid M, Munroe PB, Musk AW, Narisu N, Navis G, Neale BM, Nelis M, Nemesh J, Neville MJ, Ngwa JS, Nicholson G, Nieminen MS, Njølstad I, Nohr EA, Nolte IM, North KE, Nöthen MM, Nyholt DR, O'Connell JR, Ohlsson C, Oldehinkel AJ, van Ommen GJ, Ong KK, Oostra BA, Ouwehand WH, Palmer CN, Palmer LJ, Palotie A, Paré G, Parker AN, Paternoster L, Pawitan Y, Pechlivanis S, Peden JF, Pedersen NL, Pedersen O, Pellikka N, Peltonen L, Penninx B, Perola M, Perry JR, Person T, Peters A, Peters MJ, Pichler I, Pietiläinen KH, Platou CG, Polasek O, Pouta A, Power C, Pramstaller PP, Preuss M, Price JF, Prokopenko I, Province MA, Psaty BM, Purcell S, Pütter C, Qi L, Quertermous T, Radhakrishnan A, Raitakari O, Randall JC, Rauramaa R, Rayner NW, Rehnberg E, Rendon A, Ridderstråle M, Ridker PM, Ripatti S, Rissanen A, Rivadeneira F, Rivolta C, Robertson NR, Rose LM, Rudan I, Saaristo TE, Sager H, Salomaa V, Samani NJ, Sambrook JG, Sanders AR, Sandholt C, Sanna S, Saramies J, Schadt EE, Scherag A, Schipf S, Schlessinger D, Schreiber S, Schunkert H, Schwarz PE, Scott LJ, Shi J, Shin SY, Shuldiner AR, Shungin D, Signorini S, Silander K, Sinisalo J, Skrobek B, Smit JH, Smith AV, Smith GD, Snieder H, Soranzo N, Sørensen TI, Sovio U, Spector TD, Speliotes EK, Stančáková A, Stark K, Stefansson K, Steinthorsdottir V, Stephens JC, Stirrups K, Stolk RP, Strachan DP, Strawbridge RJ, Stringham HM, Stumvoll M, Surakka I, Swift AJ, Syvanen AC, Tammesoo ML, Teder Laving M, Teslovich TM, Teumer A, Theodoraki EV, Thomson B, Thorand B, Thorleifsson G, Thorsteinsdottir U, Timpson NJ, Tönjes A, Tregouet DA, Tremoli E, Trip MD, Tuomi T, Tuomilehto J, Tyrer J, Uda M, Uitterlinden AG, Usala G, Uusitupa M, Valle TT, Vandenput L, Vatin V, Vedantam S, de Vegt F, Vermeulen SH, Viikari J, Virtamo J, Visscher PM, Vitart V, Van Vliet Ostaptchouk JV, Voight BF, Vollenweider P, Volpato CB, Völzke H, Waeber G, Waite LL, Wallaschofski H, Walters GB, Wang Z, Wareham NJ, Watanabe RM, Watkins H, Weedon MN, Welch R, Weyant RJ, Wheeler E, White CC, Wichmann HE, Widen E, Wild SH, Willemsen G, Willer CJ, Wilsgaard T, Wilson JF, van Wingerden S, Winkelmann BR, Winkler TW, Witte DR, Witteman JC, Wolffenbuttel BH, Wong A, Wood AR, Workalemahu T, Wright AF, Yang J, Yarnell JW, Zgaga L, Zhao JH, Zillikens MC, Zitting P, Zondervan KT
Publikováno v:
Nature Protocols, 9, 1192-212
Nature protocols
Winkler, T W, Day, F R, Croteau-Chonka, D C, Wood, A R, Locke, A E, Mägi, R, Ferreira, T, Fall, T, Graff, M, Justice, A E, Luan, J, Gustafsson, S, Randall, J C, Vedantam, S, Workalemahu, T, Kilpeläinen, T O, Scherag, A, Esko, T, Kutalik, Z, Heid, I M, Loos, R J F, Boomsma, D I, de Geus, E J C, Hottenga, J J, Willemsen, G, Penninx, B W J H & Smit, J H 2014, ' Quality control and conduct of genome-wide association meta-analyses ', Nature Protocols, vol. 9, no. 5, pp. 1192-1212 . https://doi.org/10.1038/nprot.2014.071
Nature protocols, 9(5), 1192-1212. Nature Publishing Group
Nature Protocols, 9(5), 1192-1212. Nature Publishing Group
Nature Protocols, 9, 5, pp. 1192-212
Nature Protocols, 9(5), 1192-1212
Winkler, T W, Day, F R, Croteau-Chonka, D C, Wood, A R, Locke, A E, Mägi, R, Ferreira, T, Fall, T, Graff, M, Justice, A E, Luan, J, Gustafsson, S, Randall, J C, Vedantam, S, Workalemahu, T, Kilpeläinen, T O, Scherag, A, Esko, T, Kutalik, Z, Heid, I M, Loos, R J F & Genetic Investigation of Anthropometric Traits (GIANT) Consortium (Ellen A. Nøhr, Daniel R. Witte; members) 2014, ' Quality control and conduct of genome-wide association meta-analyses ', Nature Protocols, vol. 9, no. 5, pp. 1192-212 . https://doi.org/10.1038/nprot.2014.071
Nature Protocols, vol. 9, no. 5, pp. 1192-1212
Nature protocols
Winkler, T W, Day, F R, Croteau-Chonka, D C, Wood, A R, Locke, A E, Mägi, R, Ferreira, T, Fall, T, Graff, M, Justice, A E, Luan, J, Gustafsson, S, Randall, J C, Vedantam, S, Workalemahu, T, Kilpeläinen, T O, Scherag, A, Esko, T, Kutalik, Z, Heid, I M, Loos, R J F, Boomsma, D I, de Geus, E J C, Hottenga, J J, Willemsen, G, Penninx, B W J H & Smit, J H 2014, ' Quality control and conduct of genome-wide association meta-analyses ', Nature Protocols, vol. 9, no. 5, pp. 1192-1212 . https://doi.org/10.1038/nprot.2014.071
Nature protocols, 9(5), 1192-1212. Nature Publishing Group
Nature Protocols, 9(5), 1192-1212. Nature Publishing Group
Nature Protocols, 9, 5, pp. 1192-212
Nature Protocols, 9(5), 1192-1212
Winkler, T W, Day, F R, Croteau-Chonka, D C, Wood, A R, Locke, A E, Mägi, R, Ferreira, T, Fall, T, Graff, M, Justice, A E, Luan, J, Gustafsson, S, Randall, J C, Vedantam, S, Workalemahu, T, Kilpeläinen, T O, Scherag, A, Esko, T, Kutalik, Z, Heid, I M, Loos, R J F & Genetic Investigation of Anthropometric Traits (GIANT) Consortium (Ellen A. Nøhr, Daniel R. Witte; members) 2014, ' Quality control and conduct of genome-wide association meta-analyses ', Nature Protocols, vol. 9, no. 5, pp. 1192-212 . https://doi.org/10.1038/nprot.2014.071
Nature Protocols, vol. 9, no. 5, pp. 1192-1212
Item does not contain fulltext Rigorous organization and quality control (QC) are necessary to facilitate successful genome-wide association meta-analyses (GWAMAs) of statistics aggregated across multiple genome-wide association studies. This protoco
Autor:
Wood, Ar, Esko, T, Yang, J, Vedantam, S, Pers, Th, Gustafsson, S, Chu, Ay, Estrada, K, Luan, J, Kutalik, Z, Amin, N, Buchkovich, Ml, Croteau Chonka DC, Day, Fr, Duan, Y, Fall, T, Fehrmann, R, Ferreira, T, Jackson, Au, Karjalainen, J, Lo, Ks, Locke, Ae, Mägi, R, Mihailov, E, Porcu, E, Randall, Jc, Scherag, A, Vinkhuyzen, Aa, Westra, Hj, Winkler, Tw, Workalemahu, T, Zhao, Jh, Absher, D, Albrecht, E, Anderson, D, Baron, J, Beekman, M, Demirkan, A, Ehret, Gb, Feenstra, B, Feitosa, Mf, Fischer, K, Fraser, Rm, Goel, A, Gong, J, Justice, Ae, Kanoni, S, Kleber, Me, Kristiansson, K, Lim, U, Lotay, V, Lui, Jc, Mangino, M, Mateo Leach, I, Medina Gomez, C, Nalls, Ma, Nyholt, Dr, Palmer, Cd, Pasko, D, Pechlivanis, S, Prokopenko, I, Ried, Js, Ripke, S, Shungin, D, Stancáková, A, Strawbridge, Rj, Sung, Yj, Tanaka, T, Teumer, A, Trompet, S, van der Laan SW, van Setten, J, Van Vliet Ostaptchouk JV, Wang, Z, Yengo, L, Zhang, W, Afzal, U, Arnlöv, J, Arscott, Gm, Bandinelli, S, Barrett, A, Bellis, C, Bennett, Aj, Berne, C, Blüher, M, Bolton, Jl, Böttcher, Y, Boyd, Ha, Bruinenberg, M, Buckley, Bm, Buyske, S, Caspersen, Ih, Chines, Ps, Clarke, R, Claudi Boehm, S, Cooper, M, Daw, Ew, De Jong PA, Deelen, J, Delgado, G, Denny, Jc, Dhonukshe Rutten, R, Dimitriou, M, Doney, As, Dörr, M, Eklund, N, Eury, E, Folkersen, L, Garcia, Me, Geller, F, Giedraitis, V, Go, As, Grallert, H, Grammer, Tb, Gräßler, J, Grönberg, H, de Groot LC, Groves, Cj, Haessler, J, Hall, P, Haller, T, Hallmans, G, Hannemann, A, Hartman, Ca, Hassinen, M, Hayward, C, Heard Costa NL, Helmer, Q, Hemani, G, Henders, Ak, Hillege, Hl, Hlatky, Ma, Hoffmann, W, Hoffmann, P, Holmen, O, Houwing Duistermaat JJ, Illig, T, Isaacs, A, James, Al, Jeff, J, Johansen, B, Johansson, Å, Jolley, J, Juliusdottir, T, Junttila, J, Kho, An, Kinnunen, L, Klopp, N, Kocher, T, Kratzer, W, Lichtner, P, Lind, L, Lindström, J, Lobbens, S, Lorentzon, M, Lu, Y, Lyssenko, V, Magnusson, Pk, Mahajan, A, Maillard, M, Mcardle, Wl, Mckenzie, Ca, Mclachlan, S, Mclaren, Pj, Menni, C, Merger, S, Milani, L, Moayyeri, A, Monda, Kl, Morken, Ma, Müller, G, Müller Nurasyid, M, Musk, Aw, Narisu, N, Nauck, M, Nolte, Im, Nöthen, Mm, Oozageer, L, Pilz, S, Rayner, Nw, Renstrom, F, Robertson, Nr, Rose, Lm, Roussel, R, Sanna, S, Scharnagl, H, Scholtens, S, Schumacher, Fr, Schunkert, H, Scott, Ra, Sehmi, J, Seufferlein, T, Shi, J, Silventoinen, K, Smit, Jh, Smith, Av, Smolonska, J, Stanton, Av, Stirrups, K, Stott, Dj, Stringham, Hm, Sundström, J, Swertz, Ma, Syvänen, Ac, Tayo, Bo, Thorleifsson, G, Tyrer, Jp, van Dijk, S, van Schoor NM, van der Velde, N, van Heemst, D, van Oort FV, Vermeulen, Sh, Verweij, N, Vonk, Jm, Waite, Ll, Waldenberger, M, Wennauer, R, Wilkens, Lr, Willenborg, C, Wilsgaard, T, Wojczynski, Mk, Wong, A, Wright, Af, Zhang, Q, Arveiler, D, Bakker, Sj, Beilby, J, Bergman, Rn, Bergmann, S, Biffar, R, Blangero, J, Boomsma, Di, Bornstein, Sr, Bovet, P, Brambilla, P, Brown, Mj, Campbell, H, Caulfield, Mj, Chakravarti, A, Collins, R, Collins, Fs, Crawford, Dc, Cupples, La, Danesh, J, de Faire, U, den Ruijter HM, Erbel, R, Erdmann, J, Eriksson, Jg, Farrall, M, Ferrannini, Eleuterio, Ferrières, J, Ford, I, Forouhi, Ng, Forrester, T, Gansevoort, Rt, Gejman, Pv, Gieger, C, Golay, A, Gottesman, O, Gudnason, V, Gyllensten, U, Haas, Dw, Hall, As, Harris, Tb, Hattersley, At, Heath, Ac, Hengstenberg, C, Hicks, Aa, Hindorff, La, Hingorani, Ad, Hofman, A, Hovingh, Gk, Humphries, Se, Hunt, Sc, Hypponen, E, Jacobs, Kb, Jarvelin, Mr, Jousilahti, P, Jula, Am, Kaprio, J, Kastelein, Jj, Kayser, M, Kee, F, Keinanen Kiukaanniemi SM, Kiemeney, La, Kooner, Js, Kooperberg, C, Koskinen, S, Kovacs, P, Kraja, At, Kumari, M, Kuusisto, J, Lakka, Ta, Langenberg, C, Le Marchand, L, Lehtimäki, T, Lupoli, S, Madden, Pa, Männistö, S, Manunta, P, Marette, A, Matise, Tc, Mcknight, B, Meitinger, T, Moll, Fl, Montgomery, Gw, Morris, Ad, Morris, Ap, Murray, Jc, Nelis, M, Ohlsson, C, Oldehinkel, Aj, Ong, Kk, Ouwehand, Wh, Pasterkamp, G, Peters, A, Pramstaller, Pp, Price, Jf, Qi, L, Raitakari, Ot, Rankinen, T, Rao, Dc, Rice, Tk, Ritchie, M, Rudan, I, Salomaa, V, Samani, Nj, Saramies, J, Sarzynski, Ma, Schwarz, Pe, Sebert, S, Sever, P, Shuldiner, Ar, Sinisalo, J, Steinthorsdottir, V, Stolk, Rp, Tardif, Jc, Tönjes, A, Tremblay, A, Tremoli, E, Virtamo, J, Vohl, Mc, Electronic Medical Records, Genomics, Consortium, Migen, Consortium, Pagege, Consortium, LifeLines Cohort Study, Amouyel, P, Asselbergs, Fw, Assimes, Tl, Bochud, M, Boehm, Bo, Boerwinkle, E, Bottinger, Ep, Bouchard, C, Cauchi, S, Chambers, Jc, Chanock, Sj, Cooper, Rs, de Bakker PI, Dedoussis, G, Ferrucci, L, Franks, Pw, Froguel, P, Groop, Lc, Haiman, Ca, Hamsten, A, Hayes, Mg, Hui, J, Hunter, Dj, Hveem, K, Jukema, Jw, Kaplan, Rc, Kivimaki, M, Kuh, D, Laakso, M, Liu, Y, Martin, Ng, März, W, Melbye, M, Moebus, S, Munroe, Pb, Njølstad, I, Oostra, Ba, Palmer, Cn, Pedersen, Nl, Perola, M, Pérusse, L, Peters, U, Powell, Je, Power, C, Quertermous, T, Rauramaa, R, Reinmaa, E, Ridker, Pm, Rivadeneira, F, Rotter, Ji, Saaristo, Te, Saleheen, D, Schlessinger, D, Slagboom, Pe, Snieder, H, Spector, Td, Strauch, K, Stumvoll, M, Tuomilehto, J, Uusitupa, M, van der Harst, P, Völzke, H, Walker, M, Wareham, Nj, Watkins, H, Wichmann, He, Wilson, Jf, Zanen, P, Deloukas, P, Heid, Im, Lindgren, Cm, Mohlke, Kl, Speliotes, Ek, Thorsteinsdottir, U, Barroso, I, Fox, Cs, North, Ke, Strachan, Dp, Beckmann, Js, Berndt, Si, Boehnke, M, Borecki, Ib, Mccarthy, Mi, Metspalu, A, Stefansson, K, Uitterlinden, Ag, van Duijn CM, Franke, L, Willer, Cj, Price, Al, Lettre, G, Loos, Rj, Weedon, Mn, Ingelsson, E, O'Connell, Jr, Abecasis, Gr, Chasman, Di, Goddard, Me, Visscher, Pm, Hirschhorn, Jn, Frayling, T. M.
Publikováno v:
Nature genetics
Nature Genetics
Nat Genet
Nature Genetics, 46(11), 1173-86. Nature Publishing Group
Nature Genetics, 46(11), 1173-1186. Nature Publishing Group
Wood, A R, Esko, T, Yang, J, Vedantam, S, Pers, T H, Gustafsson, S, Chu, A Y, Estrada, K, Luan, J, Kutalik, Z, Amin, N, Buchkovich, M L, Croteau-Chonka, D C, Day, F R, Duan, Y, Fall, T, Fehrmann, R S, Ferreira, T, Jackson, A U, Karjalainen, J, Lo, K S, Locke, A E, Mägi, R, Mihailov, E, Porcu, E, Randall, J C, Scherag, A, Vinkhuyzen, A A E, Westra, H J, Winkler, T W, Workalemahu, T, Zhao, J H, Absher, D, Albrecht, E, Anderson, D, Baron, J, Beekman, M, Demirkan, A, Ehret, G B, Feenstra, B, Feitosa, M F, Fischer, K, Fraser, R M, Goel, A, Gong, J, Justice, A E, Kanoni, S, Kleber, M E, Kristiansson, K, Lim, U, Helmer, Q, Boomsma, D I, Saleheen, D, Schlessinger, D, Slagboom, P E, Snieder, H, Spector, T D, Strauch, K, Stumvoll, M, Tuomilehto, J, Uusitupa, M, van der Harst, P, Völzke, H, Walker, M, Wareham, N J, Watkins, H, Wichmann, H E, Wilson, J F, Zanen, P, Deloukas, P, Heid, I M, Lindgren, C M, Mohlke, K L, Speliotes, E K, Thorsteinsdottir, U, Barroso, I, Fox, C S, North, K E, Strachan, D P, Beckmann, J S, Berndt, S I, Boehnke, M, Borecki, I B, McCarthy, M I, Metspalu, A, Smit, J H, Pilz, S, van Schoor, N M, Stefansson, K, Uitterlinden, A G, van Duijn, C M, Franke, L, Willer, C J, Price, A L, Lettre, G, Loos, R J F, Weedon, M N, Ingelsson, E, O'Connell, J R, Abecasis, G R, Chasman, D I, Goddard, M E, Visscher, P M, Hirschhorn, J N & Frayling, T M 2014, ' Defining the role of common variation in the genomic and biological architecture of adult human height ', Nature Genetics, vol. 46, no. 11, pp. 1173-1186 . https://doi.org/10.1038/ng.3097
Nature Genetics, 46, 1173-1186
Nature Genetics, Vol. 46, No 11 (2014) pp. 1173-1186
Nature Genetics 46 (2014)
Nature genetics, 46(11), 1173-1186. Nature Publishing Group
Nature Genetics, 46, 1173-86
Nature Genetics, 46, 11, pp. 1173-86
Nature Genetics, vol. 46, no. 11, pp. 1173-1186
Nature Genetics, 46(11), 1173-1186
Nature Genetics
Nat Genet
Nature Genetics, 46(11), 1173-86. Nature Publishing Group
Nature Genetics, 46(11), 1173-1186. Nature Publishing Group
Wood, A R, Esko, T, Yang, J, Vedantam, S, Pers, T H, Gustafsson, S, Chu, A Y, Estrada, K, Luan, J, Kutalik, Z, Amin, N, Buchkovich, M L, Croteau-Chonka, D C, Day, F R, Duan, Y, Fall, T, Fehrmann, R S, Ferreira, T, Jackson, A U, Karjalainen, J, Lo, K S, Locke, A E, Mägi, R, Mihailov, E, Porcu, E, Randall, J C, Scherag, A, Vinkhuyzen, A A E, Westra, H J, Winkler, T W, Workalemahu, T, Zhao, J H, Absher, D, Albrecht, E, Anderson, D, Baron, J, Beekman, M, Demirkan, A, Ehret, G B, Feenstra, B, Feitosa, M F, Fischer, K, Fraser, R M, Goel, A, Gong, J, Justice, A E, Kanoni, S, Kleber, M E, Kristiansson, K, Lim, U, Helmer, Q, Boomsma, D I, Saleheen, D, Schlessinger, D, Slagboom, P E, Snieder, H, Spector, T D, Strauch, K, Stumvoll, M, Tuomilehto, J, Uusitupa, M, van der Harst, P, Völzke, H, Walker, M, Wareham, N J, Watkins, H, Wichmann, H E, Wilson, J F, Zanen, P, Deloukas, P, Heid, I M, Lindgren, C M, Mohlke, K L, Speliotes, E K, Thorsteinsdottir, U, Barroso, I, Fox, C S, North, K E, Strachan, D P, Beckmann, J S, Berndt, S I, Boehnke, M, Borecki, I B, McCarthy, M I, Metspalu, A, Smit, J H, Pilz, S, van Schoor, N M, Stefansson, K, Uitterlinden, A G, van Duijn, C M, Franke, L, Willer, C J, Price, A L, Lettre, G, Loos, R J F, Weedon, M N, Ingelsson, E, O'Connell, J R, Abecasis, G R, Chasman, D I, Goddard, M E, Visscher, P M, Hirschhorn, J N & Frayling, T M 2014, ' Defining the role of common variation in the genomic and biological architecture of adult human height ', Nature Genetics, vol. 46, no. 11, pp. 1173-1186 . https://doi.org/10.1038/ng.3097
Nature Genetics, 46, 1173-1186
Nature Genetics, Vol. 46, No 11 (2014) pp. 1173-1186
Nature Genetics 46 (2014)
Nature genetics, 46(11), 1173-1186. Nature Publishing Group
Nature Genetics, 46, 1173-86
Nature Genetics, 46, 11, pp. 1173-86
Nature Genetics, vol. 46, no. 11, pp. 1173-1186
Nature Genetics, 46(11), 1173-1186
Item does not contain fulltext Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in
Autor:
Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Boehnke M, Raychaudhuri S, Fehrmann RS, Hirschhorn JN, Franke L, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice E, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Mateo Leach I, Medina Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspersen IH, Chines PS, Clarke R, Claudi Boehm S, Cooper M, Daw EW, De Jong A, Deelen J, Delgado G, Denny JC, Dhonukshe Rutten R, Dimitriou M, Doney AS, Dörr M, Eklund N, Eury E, Folkersen L, Garcia ME, Geller F, Giedraitis V, Go AS, Grallert H, Grammer TB, Gräßler J, Grönberg H, de Groot LC, Groves CJ, Haessler J, Haller T, Hallmans G, Hannemann A, Hartman CA, Hassinen M, Hayward C, Heard Costa NL, Helmer Q, Hemani G, Henders AK, Hillege HL, Hlatky MA, Hoffmann W, Hoffmann P, Holmen O, Houwing Duistermaat JJ, Illig T, Isaacs A, James AL, Jeff J, Johansen B, Johansson Å, Jolley J, Juliusdottir T, Junttila J, Kho AN, Kinnunen L, Klopp N, Kocher T, Kratzer W, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Lu Y, Lyssenko V, Magnusson PK, Mahajan A, Maillard M, McArdle WL, McKenzie CA, McLachlan S, McLaren PJ, Menni C, Merger S, Milani L, Moayyeri A, Monda KL, Morken MA, Müller G, Müller Nurasyid M, Musk AW, Narisu N, Nauck M, Nolte IM, Nöthen MM, Oozageer L, Pilz S, Rayner NW, Renstrom F, Robertson NR, Rose LM, Roussel R, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Schunkert H, Scott RA, Sehmi J, Seufferlein T, Shi J, Silventoinen K, Smit JH, Smith AV, Smolonska J, Stanton AV, Stirrups K, Stott DJ, Stringham HM, Sundström J, Swertz MA, Syvänen AC, Tayo BO, Thorleifsson G, Tyrer JP, van Dijk S, van Schoor NM, van der Velde N, van Heemst D, van Oort FV, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Waldenberger M, Wennauer R, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boomsma I, Bornstein SR, Bovet P, BRAMBILLA, PAOLO, Brown MJ, Campbell H, Caulfield MJ, Chakravarti A, Collins R, Collins FS, Crawford DC, Cupples LA, Danesh J, de Faire U, den Ruijter HM, Erbel R, Erdmann J, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Gansevoort RT, Gejman PV, Gieger C, Golay A, Gottesman O, Gudnason V, Gyllensten U, Haas DW, Hall AS, Harris TB, Hattersley AT, Heath AC, Hengstenberg C, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Hovingh GK, Humphries SE, Hunt SC, Hypponen E, Jacobs KB, Jarvelin MR, Jousilahti P, Jula AM, Kaprio J, Kastelein JJ, Kayser M, Kee F, Keinanen Kiukaanniemi SM, Kiemeney LA, Kooner JS, Kooperberg C, Koskinen S, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lupoli S, Madden PA, Männistö S, Manunta P, Marette A, Matise TC, McKnight B, Meitinger T, Moll FL, Montgomery GW, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Ouwehand WH, Pasterkamp G, Peters A, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ritchie M, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Sebert S, Sever P, Shuldiner AR, Sinisalo J, Steinthorsdottir V, Stolk RP, Tardif JC, Tönjes A, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PI, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hayes MG, Hui J, Hunter DJ, Hveem K, Jukema JW, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, März W, Melbye M, Moebus S, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Powell JE, Power C, Quertermous T, Rauramaa R, Reinmaa E, Ridker PM, Rivadeneira F, Rotter JI, Saaristo TE, Saleheen D, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Strauch K, Stumvoll M, Tuomilehto J, Uusitupa M, van der Harst P, Völzke H, Walker M, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Zanen P, Deloukas P, Heid IM, Lindgren CM, Mohlke KL, Thorsteinsdottir U, Barroso I, Fox CS, North KE, Strachan DP, Beckmann JS, Berndt SI, Borecki IB, McCarthy MI, Metspalu A, Stefansson K, Uitterlinden AG, van Duijn CM, Willer CJ, Price AL, Lettre G, Loos RJ, Weedon MN, Ingelsson E, O'Connell JR, Abecasis GR, Chasman DI, Goddard ME, Visscher PM, Frayling T.M.
Publikováno v:
Nature Communications, 6:5890. Nature Publishing Group
Europe PubMed Central
Nature Communications, vol. 6, pp. 5890
Nature Communications, 6, 5890
Nature Communications
Nature Communications [E], 6, 5890. Nature Publishing Group
Pers, T H, Karjalainen, J M, Chan, Y, Westra, H-J, Wood, A R, Yang, J, Lui, J C, Vedantam, S, Gustafsson, S, Esko, T, Frayling, T, Speliotes, E K, Boehnke, M, Raychaudhuri, S, Fehrmann, R S N, Hirschhorn, J N, Franke, L, McLachlan, S, Campbell, H, Price, J & Rudan, I & Wilson, J 2015, ' Biological interpretation of genome-wide association studies using predicted gene functions ', Nature Communications, vol. 6, 5890 . https://doi.org/10.1038/ncomms6890
Nature Communications, 6, pp. 5890
Nature communications, 6. Nature Publishing Group
Europe PubMed Central
Nature Communications, vol. 6, pp. 5890
Nature Communications, 6, 5890
Nature Communications
Nature Communications [E], 6, 5890. Nature Publishing Group
Pers, T H, Karjalainen, J M, Chan, Y, Westra, H-J, Wood, A R, Yang, J, Lui, J C, Vedantam, S, Gustafsson, S, Esko, T, Frayling, T, Speliotes, E K, Boehnke, M, Raychaudhuri, S, Fehrmann, R S N, Hirschhorn, J N, Franke, L, McLachlan, S, Campbell, H, Price, J & Rudan, I & Wilson, J 2015, ' Biological interpretation of genome-wide association studies using predicted gene functions ', Nature Communications, vol. 6, 5890 . https://doi.org/10.1038/ncomms6890
Nature Communications, 6, pp. 5890
Nature communications, 6. Nature Publishing Group
Article
The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systemati
The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c01dc19a09cb0c6a0e1b23d60806ae
https://research.rug.nl/en/publications/8a846281-7fe7-4c98-b8a2-a4009f931264
https://research.rug.nl/en/publications/8a846281-7fe7-4c98-b8a2-a4009f931264
Publikováno v:
Zeitschrift für Rheumatologie. 66:556-561
In highly industrialized countries hyperuricemia is one of the most common metabolic disorders. High uric acid blood levels may lead to the manifestation of gout owing to the precipitation of urate crystals in connective tissue, the skeletal system a
Autor:
Strawbridge, Rj, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, Jr, Travers, Me, Bouatia Naji, N, Dimas, As, Nica, A, Wheeler, E, Chen, H, Voight, Bf, Taneera, J, Kanoni, S, Peden, Jf, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, Dj, Barnes, D, Dennison, Em, Eriksson, Jg, Eriksson, P, Eury, E, Folkersen, L, Fox, Cs, Frayling, Tm, Goel, A, Gu, Hf, Horikoshi, M, Isomaa, B, Jackson, Au, Jameson, Ka, Kajantie, E, Kerr Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, Rj, Luan, J, Makrilakis, K, Manning, Ak, Martínez Larrad MT, Narisu, N, Nastase Mannila, M, Ohrvik, J, Osmond, C, Pascoe, L, Payne, F, Sayer, Aa, Sennblad, B, Silveira, A, Stancáková, A, Stirrups, K, Swift, Aj, Syvänen, Ac, Tuomi, T, van 't Hooft FM, Walker, M, Weedon, Mn, Xie, W, Zethelius, B, Diagram, Consortium, Giant, Consortium, Muther, Consortium, Cardiogram, Consortium, C4d, Consortium, Ongen, H, Mälarstig, A, Hopewell, Jc, Saleheen, D, Chambers, J, Parish, S, Danesh, J, Kooner, J, Ostenson, Cg, Lind, L, Cooper, Cc, Serrano Ríos, M, Ferrannini, E, Forsen, Tj, Clarke, R, Franzosi, Mg, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, Fs, Laakso, M, Dermitzakis, Et, Boehnke, M, Mccarthy, Mi, Wareham, Nj, Groop, L, Pattou, F, Gloyn, Al, Dedoussis, Gv, Lyssenko, V, Meigs, Jb, Barroso, I, Watanabe, Rm, Ingelsson, E, Langenberg, C, Hamsten, A, Voight BF, Florez J. C., Scott, Lj, Steinthorsdottir, V, Morris, Ap, Dina, C, Welch, Rp, Zeggini, E, Huth, C, Aulchenko, Ys, Thorleifsson, G, Mcculloch, Lj, Ferreira, T, Grallert, H, Amin, N, Wu, G, Willer, Cj, Raychaudhuri, S, Mccarroll, Sa, Hofmann, Om, Qi, L, Segrè, Av, van Hoek, M, Navarro, P, Ardlie, K, Balkau, B, Benediktsson, R, Bennett, Aj, Blagieva, R, Boerwinkle, E, Bonnycastle, Ll, Bengtsson Boström, K, Bravenboer, B, Bumpstead, S, Burtt, P, Charpentier, G, Chines, Ps, Cornelis, M, Couper, Dj, Crawford, G, Doney, As, Elliott, Ks, Elliott, Al, Erdos, Mr, Franklin, Cs, Gieger, C, Grarup, N, Green, T, Griffin, S, Groves, Cj, Guiducci, C, Hadjadj, S, Hassanali, N, Herder, C, Johnson, Pr, Jørgensen, T, Kao, Wh, Klopp, N, Kong, A, Kraft, P, Lauritzen, T, Li, M, Lieverse, A, Lindgren, Cm, Marre, M, Meitinger, T, Midthjell, K, Morken, Ma, Nilsson, P, Owen, Kr, Perry, Jr, Petersen, K, Platou, C, Proença, C, Rathmann, W, William Rayner, N, Robertson, Nr, Rocheleau, G, Roden, M, Sampson, Mj, Saxena, R, Shields, Bm, Shrader, P, Sigurdsson, G, Sparsø, T, Strassburger, K, Stringham, Hm, Sun, Q, Thorand, B, Tichet, J, van Dam RM, van Haeften TW, van Herpt, T, van Vliet JV, Bragi Walters, G, Wijmenga, C, Witteman, J, Bergman, Rn, Cauchi, S, Gyllensten, U, Hansen, T, Hide, Wa, Hitman, Ga, Hofman, A, Hunter, Dj, Hveem, K, Mohlke, Kl, Morris, Ad, Palmer, Cn, Pramstaller, Pp, Rudan, I, Sijbrands, E, Stein, Ld, Tuomilehto, J, Uitterlinden, A, Abecasis, Gr, Boehm, Bo, Campbell, H, Daly, Mj, Hattersley, At, Hu, Fb, Pankow, Js, Pedersen, O, Wichmann, E, Florez, Jc, Sladek, R, Thorsteinsdottir, U, Wilson, Jf, Illig, T, Stefansson, K, Altshuler, D, Speliotes, Ek, Berndt, Si, Monda, Kl, Allen, Hl, Mägi, R, Randall, Jc, Vedantam, S, Winkler, Tw, Workalemahu, T, Heid, Im, Wood, Ar, Weyant, Rj, Estrada, K, Liang, L, Nemesh, J, Park, Jh, Kilpeläinen, To, Yang, J, Esko, T, Feitosa, Mf, Kutalik, Z, Mangino, M, Scherag, A, Smith, Av, Welch, R, Zhao, Jh, Aben, Kk, Absher, Dm, Dixon, Al, Fisher, E, Glazer, Nl, Goddard, Me, Heard Costa NL, Hoesel, V, Hottenga, Jj, Johansson, Å, Johnson, T, Ketkar, S, Lamina, C, Li, S, Moffatt, Mf, Myers, Rh, Peters, Mj, Preuss, M, Ripatti, S, Rivadeneira, F, Sandholt, C, Timpson, Nj, Tyrer, Jp, van Wingerden, S, White, Cc, Wiklund, F, Barlassina, C, Chasman, Di, Cooper, Mn, Jansson, Jo, Lawrence, Rw, Pellikka, N, Shi, J, Thiering, E, Alavere, H, Alibrandi, Mt, Arnold, Am, Aspelund, T, Atwood, Ld, Balmforth, Aj, Ben Shlomo, Y, Bergmann, S, Biebermann, H, Blakemore, Ai, Boes, T, Bornstein, Sr, Brown, Mj, Buchanan, Ta, Busonero, F, Cappuccio, Fp, Cavalcanti Proença, C, Ida Chen YD, Chen, Cm, Coin, L, Connell, J, Day, In, den Heijer, M, Duan, J, Ebrahim, S, Elliott, P, Elosua, R, Eiriksdottir, G, Facheris, Mf, Felix, Sb, Fischer Posovszky, P, Folsom, Ar, Friedrich, N, Freimer, Nb, Fu, M, Gaget, S, Gejman, Pv, Geus, Ej, Gjesing, Ap, Goyette, P, Grässler, J, Greenawalt, Dm, Gudnason, V, Hartikainen, Al, Hall, As, Havulinna, As, Hayward, C, Heath, Ac, Hengstenberg, C, Hicks, Aa, Hinney, A, Homuth, G, Hui, J, Igl, W, Iribarren, C, Jacobs, Kb, Jarick, I, Jewell, E, John, U, Jousilahti, P, Jula, A, Kaakinen, M, Kaplan, Lm, Kathiresan, S, Kettunen, J, Kinnunen, L, Knowles, Jw, Kolcic, I, König, Ir, Koskinen, S, Kovacs, P, Kvaløy, K, Laitinen, J, Lantieri, O, Lanzani, C, Launer, Lj, Lecoeur, C, Terho, L, Lettre, G, Liu, J, Lokki, Ml, Lorentzon, M, Luben, Rn, Ludwig, B, Magic, Manunta, P, Marek, D, Martin, Ng, Mcardle, Wl, Mccarthy, A, Mcknight, B, Melander, O, Meyre, D, Montgomery, Gw, Mulic, R, Ngwa, Js, Nelis, M, Neville, Mj, Nyholt, Dr, O'Donnell, Cj, O'Rahilly, S, Ong, Kk, Oostra, B, Paré, G, Parker, An, Perola, M, Pichler, I, Pietiläinen, Kh, Platou, Cg, Polasek, O, Pouta, A, Rafelt, S, Raitakari, O, Rayner, Nw, Ridderstråle, M, Rief, W, Ruokonen, A, Rzehak, P, Salomaa, V, Sanders, Ar, Sandhu, Ms, Sanna, S, Saramies, J, Savolainen, Mj, Scherag, S, Schipf, S, Schreiber, S, Schunkert, H, Silander, K, Sinisalo, J, Siscovick, Ds, Smit, Jh, Soranzo, N, Sovio, U, Stephens, J, Surakka, I, Tammesoo, Ml, Tardif, Jc, Teder Laving, M, Teslovich, Tm, Thompson, Jr, Thomson, B, Tönjes, A, van Meurs JB, van Ommen GJ, Vatin, V, Viikari, J, Visvikis Siest, S, Vitart, V, Vogel, Ci, Waite, Ll, Wallaschofski, H, Walters, Gb, Widen, E, Wiegand, S, Wild, Sh, Willemsen, G, Witte, Dr, Witteman, Jc, Xu, J, Zhang, Q, Zgaga, L, Ziegler, A, Zitting, P, Beilby, Jp, Farooqi, Is, Hebebrand, J, Huikuri, Hv, James, Al, Kähönen, M, Levinson, Df, Macciardi, F, Nieminen, Ms, Ohlsson, C, Palmer, Lj, Ridker, Pm, Stumvoll, M, Beckmann, Js, Boeing, H, Dorret, I. 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S.
Publikováno v:
Morris, A & Rudan, I & Campbell, H & Wilson, J 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-34 . https://doi.org/10.2337/db11-0415
Diabetes; Vol 60
Diabetes, Vol. 60, No 10 (2011) pp. 2624-34
Diabetes, 60(10), 2624-2634. American Diabetes Association Inc.
Diabetes, 60, 2624-34
Diabetes, 60(10), 2624-2634. AMER DIABETES ASSOC
Diabetes
Diabetes, 60, 10, pp. 2624-34
Diabetes, 60(10), 2624-2634
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Travers, M E, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Peden, J F, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, D J P, Barnes, D, Dennison, E M, Eriksson, J G, Eriksson, P, Eury, E, Folkersen, L, Fox, C S, Frayling, T M, Goel, A, Gu, H F, Horikoshi, M, Isomaa, B, Jackson, A U, Jameson, K A, Kajantie, E, Kerr-Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, R J F, Luan, J, Makrilakis, K, Manning, A K, Martínez-Larrad, M T, Narisu, N, Mannila, M N, the DIAGRAM Consortium (Torsten Lauritzen, Niels Grarup; members), the GIANT Consortium (Daniel R. Witte; member), the MuTHER Consortium, the CARDIoGRAM Consortium & the C4D Consortium 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Forsen, T J, Clarke, R, Franzosi, M G, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, F S, Laakso, M, Dermitzakis, E T, Boehnke, M, McCarthy, M I, Wareham, N J, Groop, L, Pattou, F, Gloyn, A L, Dedoussis, G V, Lyssenko, V, Meigs, J B, Barroso, I, Watanabe, R M, Ingelsson, E, Langenberg, C, Hamsten, A & Florez, J C 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Diabetes; Vol 60
Diabetes, Vol. 60, No 10 (2011) pp. 2624-34
Diabetes, 60(10), 2624-2634. American Diabetes Association Inc.
Diabetes, 60, 2624-34
Diabetes, 60(10), 2624-2634. AMER DIABETES ASSOC
Diabetes
Diabetes, 60, 10, pp. 2624-34
Diabetes, 60(10), 2624-2634
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Travers, M E, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Peden, J F, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, D J P, Barnes, D, Dennison, E M, Eriksson, J G, Eriksson, P, Eury, E, Folkersen, L, Fox, C S, Frayling, T M, Goel, A, Gu, H F, Horikoshi, M, Isomaa, B, Jackson, A U, Jameson, K A, Kajantie, E, Kerr-Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, R J F, Luan, J, Makrilakis, K, Manning, A K, Martínez-Larrad, M T, Narisu, N, Mannila, M N, the DIAGRAM Consortium (Torsten Lauritzen, Niels Grarup; members), the GIANT Consortium (Daniel R. Witte; member), the MuTHER Consortium, the CARDIoGRAM Consortium & the C4D Consortium 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Forsen, T J, Clarke, R, Franzosi, M G, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, F S, Laakso, M, Dermitzakis, E T, Boehnke, M, McCarthy, M I, Wareham, N J, Groop, L, Pattou, F, Gloyn, A L, Dedoussis, G V, Lyssenko, V, Meigs, J B, Barroso, I, Watanabe, R M, Ingelsson, E, Langenberg, C, Hamsten, A & Florez, J C 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
OBJECTIVE Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca4fdf7c5b7d3a200245a047f2fc720
https://hdl.handle.net/20.500.11820/d6fd0145-660e-41a0-96e6-84d3af65fb9b
https://hdl.handle.net/20.500.11820/d6fd0145-660e-41a0-96e6-84d3af65fb9b
Autor:
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Publikováno v:
Nature, vol. 518, no. 7538, pp. 187-196
Nature
Nature, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature 518(7538), 187-196 (2015). doi:10.1038/nature14132
Nature, 518(7538), 187-U378. Nature Publishing Group
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature, 518(7538), 187-196. Nature Publishing Group
Nature, 518(7538), 187. Nature Publishing Group
Nature, 518(7538), 187-U378
Shungin, D, Winkler, T W, Croteau-Chonka, D C, Ferreira, T, Lockes, A E, Maegi, R, Strawbridge, R J, Pers, T H, Fischer, K, Justice, A E, Workalemahu, T, Wu, J M W, Buchkovich, M L, Heard-Costa, N L, Roman, T S, Drong, A W, Song, C, Gustafsson, S, Day, F R, Esko, T, Fall, T, Kutalik, Z, Luan, J, Randall, J C, Scherag, A, Vedantam, S, Wood, A R, Chen, J, Fehrmann, R, Karjalainen, J, Kahali, B, Liu, C, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M, Bragg-Gresham, J L, Buyske, S, Demirkan, A, Ehret, G B, Feitosa, M F, Goel, A, Jackson, A U, Johnson, T, Kleber, M E, Kristiansson, K, Mangino, M, Leach, I M, Medina-Gomez, C, Palmer, C D, Pasko, D, Pechlivaniss, S, Peters, MJ, Prokopenko, I, Stancakova, A, Sung, Y J, Tanakam, T, Teumer, A, van Vliet-Ostaptchouk, J V, Yengo, L, Zhang, W, Albrecht, E, Arnlov, J, Arscott, G M, Bandinelli, S, Barrett, A, Bellis, C, Bennett, A J, Berne, C, Blueher, M, Buhringer, S, Bonnet, F, Boettcher, Y, Bruinenberg, M, Carba, D B, Caspersen, I H, 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Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. 〈10.1038/nature14132〉
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature
Nature, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature
Nature, 518(7538), 187-U378. Nature Publishing Group
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature, 518(7538), 187-196. Nature Publishing Group
Nature, 518(7538), 187. Nature Publishing Group
Nature, 518(7538), 187-U378
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Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. 〈10.1038/nature14132〉
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85bfcecc21bc571d9b494c320c32aef
https://serval.unil.ch/notice/serval:BIB_10C25BFE14DB
https://serval.unil.ch/notice/serval:BIB_10C25BFE14DB
Autor:
Peter Kovacs, Alan F. Wright, Stephen Turner, Michèle M. Sale, Siim Sõber, Janoš Terzić, Elin Org, Richard S. Cooper, Alena Stančáková, Jerome I. Rotter, W. H. Linda Kao, Albert Hofman, Andrew B. Singleton, Florian Kronenberg, Jianjun Liu, Nicole L. Glazer, Christopher W. Knouff, Jennifer L. Bragg-Gresham, Juha Karjalainen, Li Ching Chang, Benjamin J. Wright, Jacqueline C.M. Witteman, Martin G. Larson, Klaus Stark, Richard J. Rodeheffer, Sharon L.R. Kardia, Douglas M. Ruderfer, Sheila Ulivi, Madhumathi Rao, Andrew A. Hicks, Eva Brand, Viviane Nicaud, Stephen G. Ball, Anna Köttgen, Germaine C. Verwoert, Anders Hamsten, Nick Shrine, Uwe Völker, Stefan Kloiber, Stephen Hancock, Emelia J. Benjamin, Bok Ghee Han, Kenneth Rice, Mark Woodward, Veronique Vitart, Karl Andersen, Nicholas J. Wareham, Robert Roberts, Maja Barbalić, David Couper, Yukinori Okada, André G. Uitterlinden, Sekar Kathiresan, Leo-Pekka Lyytikäinen, Pankaj Arora, Tatijana Zemunik, David S. Siscovick, Simonetta Guarrera, Dawn M. Waterworth, Tatjana Stojakovic, Braxton D. Mitchell, Devin Absher, Carmen A. Peralta, Mika Kivimäki, Xueling Sim, Norihiro Kato, Philippe Froguel, Keith L. Keene, Donna K. Arnett, Naoyuki Kamatani, Tazeen H. Jafar, Idris Guessous, Gunnar Jacobs, Michael M. Hoffmann, Kari Stefansson, Christian Hengstenberg, Tomonori Okamura, Inga Prokopenko, Christina Willenborg, Peter S. Braund, Rainer Rettig, Francesco U.S. Mattace-Raso, Vikal Tripathy, F. Gerald R. Fowkes, Laura R. Loehr, Harry Campbell, Margherita Cavalieri, Olle Melander, Hao Mei, I. Mateo Leach, Nicholette D. Palmer, Eva Albrecht, Naoharu Iwai, Stefan Martin Brand, Toshiko Tanaka, Jackie A. Cooper, Omri Gottesman, Manuela Uda, Angelo Scuteri, Aroon D. Hingorani, Cristiano Fava, Yusuke Nakamura, Jiang He, Min Jin Go, Serge Hercberg, Wendy L. McArdle, Philipp S. Wild, Florian Ernst, Paul Mitchell, Wolfgang Koenig, Caroline S. Fox, S. J.Cathy Fann, Janine F. Felix, Anna F. Dominiczak, Mike A. 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Stafford, Maksim Struchalin, Arne Schillert, Jacques S. Beckmann, Mark E. Cooper, Jean-Charles Lambert, Mario Pirastu, Katja Butterbach, Carl G. P. Platou, Yan V. Sun, Marcus Fischer, Maciej Tomaszewski, Karl Werdan, Peng Chen, Daniel J. Rader, Thomas Münzel, Lowell F. Satler, Tom R. Gaunt, Brenda W.J.H. Penninx, William H. Matthai, John Whitfield, Rita P.S. Middelberg, Margus Viigimaa, Toshihiro Tanaka, Ida Yii Der Chen, Morris J. Brown, Valur Emilsson, J. Viikari, Wolfgang Lieb, Stephen E. Epstein, Harald Dobnig, Aravinda Chakravarti, Patrick Linsel-Nitschke, Stefan Pilz, Angela Doering, Sarah H. Wild, Patricia B. Munroe, Megan E. Rudock, Nicole Probst-Hensch, Danish Saleheen, Diederick E. Grobbee, Anke Tönjes, Narisu Narisu, Annika Rosengren, Masato Isono, Catherine Helmer, M. J.Kranthi Kumar, Alanna C. Morrison, Kay-Tee Khaw, Tanja Zeller, Jeffrey R. O'Connell, Christian Müller, Georg Homuth, Giriraj R. Chandak, Pankaj Sharma, Marcus Dörr, Veikko Salomaa, Paul F. O'Reilly, David Hadley, Hermann Brenner, Paolo Gasparini, Nanette R. Lee, Bamidele O. Tayo, Robert Clarke, Henri Wallaschofski, Marketa Sjögren, Abbas Dehghan, Melanie Waldenberger, Neil Risch, Vasyl Pihur, Jessica D. Faul, François Cambien, Christian Fuchsberger, Nicholas G. Martin, John C. Chambers, Zouhair Aherrahrou, Karl J. Lackner, Leif Groop, Matthias Olden, Wiek H. van Gilst, Mathias Gorski, Yvonne T. van der Schouw, Patrick Diemert, Christoph Bickel, Yik Ying Teo, Giorgio Pistis, Ruth J. F. Loos, Gudrun Veldre, Thorsten Reffelmann, Lude Franke, Karen L. Mohlke, Stefan Blankenberg, Massimo Mangino, Ian N. M. Day, Atsushi Takahashi, Alan B. Zonderman, Hua Tang, Reijo Laaksonen, Holly Kramer, Gary C. Curhan, Adrienne Tin, Talin Haritunians, Loic Yengo, Philip Howard, Arnika Kathleen Wagner, Anna Maria Corsi, Yen Pei C. Chang, Karin Halina Greiser, Jeanette Erdmann, Solveig Gretarsdottir, Sanjay Kinra, Alex Parker, Belen Ponte, Marina Ciullo, Michael Preuss, Tin Aung, Nicholas L. Smith, Michiaki Kubo, Richard N. Bergman, Alan S. Go, Patricia P. Chang, Gudmundur Thorgeirsson, Christa Meisinger, Gonçalo R. Abecasis, Maria Blettner, Jaana Laitinen, Daniel Taliun, Carlos Iribarren, Paavo Zitting, Thomas Lumley, Andreas Meinitzer, Wayne D. Rosamond, Daehee Kang, Johanne Tremblay, Stephan B. Felix, Colin A. McKenzie, Yuan-Tsong Chen, Lyudmyla Kedenko, Mladen Boban, Fadi J. Charchar, Adebowale Adeyemo, Brendan M. Buckley, Jennifer A. Smith, Reinhold Schmidt, Jaspal S. Kooner, Gavin Lucas, Paul Elliott, Dorairajan Prabhakaran, Tune H. Pers, Tunde Salako, Terrence Forrester, Paul Burton, Jeffrey R. Gulcher, Kelly A. Volcik, Richard M. Myers, Andreas Tomaschitz, H.-Erich Wichmann, Jie Yao, Giuseppe Matullo, Carsten A. Böger, Henry Völzke, Daniela Ruggiero, Federico Murgia, Yoshikuni Kita, Augustine Kong, Giovanni Gambaro, Cinzia Sala, Peter P. Pramstaller, James Scott, Maris Laan, Laura J. Scott, Alistair S. Hall, Sanaz Sedaghat, James F. Wilson, Joanne M. 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Bottinger, Roberto Elosua, Andrew Wong, Vladan Mijatovic, Maija K. Garnaas, Robert Zweiker, Joel N. Hirschhorn, Winfried März, Nilesh J. Samani, Inke R. König, Frank B. Hu, Marcus E. Kleber, Francis S. Collins, Elena Rochtchina, Ewa Zukowska-Szczechowska, Yong Li, Ayse Demirkan, Gina Hilton, G. Ehret, Thomas H. Mosley, Markus Perola, Alexandre F.R. Stewart, Josef Coresh, Olli T. Raitakari, Feng Zhang, Mark Lathrop, Michael Marmot, Yanbin Dong, Christopher J. O'Donnell, Kristin D. Marciante, Asif Rasheed, Mary F. Feitosa, Mary Susan Burnett, Rory Collins, J. Wouter Jukema, Nele Friedrich, Aida Karina Dieffenbach, Ying Wu, Yoon Shin Cho, Aaron Isaacs, Haidong Zhu, Marie Metzger, Myriam Alexander, Tanja B. Grammer, Tatiana Kuznetsova, Dabeeru C. Rao, Jayashri Aragam, Augusto D. Pichard, Jaakko Tuomilehto, Louise V. Wain, Elizabeth J. Atkinson, Tim D. Spector, Reedik Mägi, Tiit Nikopensius, Kenneth M. Kent, Guangju Zhai, Andrew D. Johnson, Menno Pruijm, David P. Strachan, Martin D. 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Publikováno v:
Nat Commun
NATURE COMMUNICATIONS
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Nature Communications, 7. Nature Publishing Group
Nature communications 7 (2016): 10023. doi:10.1038/ncomms10023
info:cnr-pdr/source/autori:Cristian Pattaro 1, Alexander Teumer 2 3, Mathias Gorski 4 5, Audrey Y Chu 6, Man Li 7, Vladan Mijatovic 8, Maija Garnaas 9, Adrienne Tin 7, Rossella Sorice 10, Yong Li 11, Daniel Taliun 1, Matthias Olden 4 5, Meredith Foster 12, Qiong Yang 13, Ming-Huei Chen 13 14, Tune H Pers 15 16, Andrew D Johnson 17, Yi-An Ko 18, Christian Fuchsberger 1, Bamidele Tayo 19, Michael Nalls 20, Mary F Feitosa 21, Aaron Isaacs 22 23, Abbas Dehghan 24, Pio d'Adamo 25, Adebowale Adeyemo 26, Aida Karina Dieffenbach 27 28, Alan B Zonderman 29, Ilja M Nolte 30, Peter J van der Most 30, Alan F Wright 31, Alan R Shuldiner 32 33, Alanna C Morrison 34, Albert Hofman 24, Albert V Smith 35 36, Albert W Dreisbach 37, Andre Franke 38, Andre G Uitterlinden 39, Andres Metspalu 40 41, Anke Tonjes 42, Antonio Lupo 43, Antonietta Robino 25, Åsa Johansson 44, Ayse Demirkan 22, Barbara Kollerits 45, Barry I Freedman 46, Belen Ponte 47, Ben A Oostra 48, Bernhard Paulweber 49, Bernhard K Krämer 50, Braxton D Mitchell 32 33, Brendan M Buckley 51, Carmen A Peralta 52, Caroline Hayward 31, Catherine Helmer 53 54, Charles N Rotimi 26, Christian M Shaffer 55, Christian Müller 56 57, Cinzia Sala 58, Cornelia M van Duijn 22, Aude Saint-Pierre 1 59, Daniel Ackermann 47, Daniel Shriner 26, Daniela Ruggiero 10, Daniela Toniolo 58 60, Yingchang Lu 61, Daniele Cusi 62, Darina Czamara 63, David Ellinghaus 38, David S Siscovick 64, Douglas Ruderfer 65, Christian Gieger 66, Harald Grallert 67 68 69, Elena Rochtchina 70, Elizabeth J Atkinson 71, Elizabeth G Holliday 72 73, Eric Boerwinkle 34, Erika Salvi 62, Erwin P Bottinger 61, Federico Murgia 74, Fernando Rivadeneira 39, Florian Ernst 2, Florian Kronenberg 45, Frank B Hu 75, Gerjan J Navis 76, Gary C Curhan 77, George B Ehret 78, Georg Homuth 2, Stefan Coassin 45, Gian-Andri Thun 79 80, Giorgio Pistis 58, Giovanni Gambaro 81, Giovanni Malerba 8, Grant W Montgomery 82, Gudny Eiriksdottir 35, Gunnar Jacobs 83, Guo Li 64, H-Erich Wichmann 84 85 86, Harry Campbell 87, Helena Schmidt 88, Henri Wallaschofski 89 90, Henry Völzke 3 90, Hermann Brenner 27 28, Heyo K Kroemer 91, Holly Kramer 19, Honghuang Lin 92, I Mateo Leach 93, Ian Ford 94, Idris Guessous 95 96 97, Igor Rudan 87, Inga Prokopenko 98, Ingrid Borecki 21, Iris M Heid 4 66, Ivana Kolcic 99, Ivana Persico 74, J Wouter Jukema 100 101 102 103, James F Wilson 87, Janine F Felix 24, Jasmin Divers 104, Jean-Charles Lambert 105, Jeanette M Stafford 104, Jean-Michel Gaspoz 95, Jennifer A Smith 106, Jessica D Faul 107, Jie Jin Wang 108, Jingzhong Ding 109, Joel N Hirschhorn 15 16 110, John Attia 71 72, John B Whitfield 82, John Chalmers 111, Jorma Viikari 112, Josef Coresh 7 113, Joshua C Denny 114, Juha Karjalainen 115, Jyotika K Fernandes 116, Karlhans Endlich 117, Katja Butterbach 27, Keith L Keene 118, Kurt Lohman 46, Laura Portas 74, Lenore J Launer 119, Leo-Pekka Lyytikäinen 120, Loic Yengo 121 122 123, Lude Franke 115, Luigi Ferrucci 124, Lynda M Rose 6, Lyudmyla Kedenko 49, Madhumathi Rao 12, Maksim Struchalin 125 126, Marcus E Kleber 127, Margherita Cavalieri 128, Margot Haun 45, Marilyn C Cornelis 75, Marina Ciullo 10, Mario Pirastu 74, Mariza de Andrade 71, Mark A McEvoy 129, Mark Woodward 7 111 112 130, Martin Adam 79 80, Massimiliano Cocca 58, Matthias Nauck 89 90, Medea Imboden 79 80, Melanie Waldenberger 67, Menno Pruijm 131, Marie Metzger 132, Michael Stumvoll 42, Michele K Evans 133, Michele M Sale 134, Mika Kähönen 135, Mladen Boban 99, Murielle Bochud 136, Myriam Rheinberger 5, Niek Verweij 93, Nabila Bouatia-Naji 137 138, Nicholas G Martin 82 139, Nick Hastie 31, Nicole Probst-Hensch 79 80, Nicole Soranzo 140, Olivier Devuyst 141, Olli Raitakari 142, Omri Gottesman 61, Oscar H Franco 24, Ozren Polasek 99, Paolo Gasparini 25, Patricia B Munroe 143 144, Paul M Ridker 145, Paul Mitchell 108, Paul Muntner 146 147, Christa Meisinger 68, Johannes H Smit 148, ICBP Consortium; AGEN Consortium; CARDIOGRAM; CHARGe-Heart Failure Group; ECHOGen Consortium; Peter Kovacs 149, Philipp S Wild 150, Philippe Froguel 121 122 123, Rainer Rettig 151, Reedik Mägi 40, Reiner Biffar 152, Reinhold Schmidt 128, Rita P S Middelberg 82, Robert J Carroll 114, Brenda W Penninx 148, Rodney J Scott 153, Ronit Katz 154, Sanaz Sedaghat 24, Sarah H Wild 87, Sharon L R Kardia 106, Sheila Ulivi 155, Shih-Jen Hwang 17, Stefan Enroth 44, Stefan Kloiber 63, Stella Trompet 100, Benedicte Stengel 132, Stephen J Hancock 72 73, Stephen T Turner 156, Sylvia E Rosas 18, Sylvia Stracke 105 157, Tamara B Harris 119, Tanja Zeller 56 57, Tatijana Zemunik 99, Terho Lehtimäki 120, Thomas Illig 68, Thor Aspelund 35 36, Tiit Nikopensius 40 41, Tonu Esko 15 40 41, Toshiko Tanaka 124, Ulf Gyllensten 44, Uwe Völker 2 90, Valur Emilsson 35 158, Veronique Vitart 31, Ville Aalto 159, Vilmundur Gudnason 35 36, Vincent Chouraki 105, Wei-Min Chen 134, Wilmar Igl 44, Winfried März 160, Wolfgang Koenig 161, Wolfgang Lieb 83, Ruth J F Loos 61 162, Yongmei Liu 46, Harold Snieder 30, Peter P Pramstaller 1 163 164, Afshin Parsa 165, Jeffrey R O'Connell 32, Katalin Susztak 18, Pavel Hamet 166, Johanne Tremblay 166, Ian H de Boer 154, Carsten A Böger 5, Wolfram Goessling 9, Daniel I Chasman 6 145, Anna Köttgen 7 11, W H Linda Kao 7 113, Caroline S Fox 17 167. Collaborators: Goncalo R Abecasis, Linda S Adair, Myriam Alexander, David Altshuler, Najaf Amin, Dan E Arking, Pankaj Arora, Yurii Aulchenko, Stephan J L Bakker, Stefania Bandinelli, Ines Barroso, Jacques S Beckmann, John P Beilby, Richard N Bergman, Sven Bergmann, Joshua C Bis, Michael Boehnke, Lori L Bonnycastle, Stefan R Bornstein, Michiel L Bots, Jennifer L Bragg-Gresham, Stefan-Martin Brand, Eva Brand, Peter S Braund, Morris J Brown, Paul R Burton, Juan P Casas, Mark J Caulfield, Aravinda Chakravarti, John C Chambers, Giriraj R Chandak, Yen-Pei C Chang, Fadi J Charchar, Nish Chaturvedi, Yoon Shin Cho, Robert Clarke, Francis S Collins, Rory Collins, John M Connell, Jackie A Cooper, Matthew N Cooper, Richard S Cooper, Anna Maria Corsi, Marcus Dörr, Santosh Dahgam, John Danesh, George Davey Smith, Ian N M Day, Panos Deloukas, Matthew Denniff, Anna F Dominiczak, Yanbin Dong, Ayo Doumatey, Paul Elliott, Roberto Elosua, Jeanette Erdmann, Susana Eyheramendy, Martin Farrall, Cristiano Fava, Terrence Forrester, F Gerald R Fowkes, Ervin R Fox, Timothy M Frayling, Pilar Galan, Santhi K Ganesh, Melissa Garcia, Tom R Gaunt, Nicole L Glazer, Min Jin Go, Anuj Goel, Jürgen Grässler, Diederick E Grobbee, Leif Groop, Simonetta Guarrera, Xiuqing Guo, David Hadley, Anders Hamsten, Bok-Ghee Han, Rebecca Hardy, Anna-Liisa Hartikainen, Simon Heath, Susan R Heckbert, Bo Hedblad, Serge Hercberg, Dena Hernandez, Andrew A Hicks, Gina Hilton, Aroon D Hingorani, Judith A Hoffman Bolton, Jemma C Hopewell, Philip Howard, Steve E Humphries, Steven C Hunt, Kristian Hveem, M Arfan Ikram, Muhammad Islam, Naoharu Iwai, Marjo-Riitta Jarvelin, Anne U Jackson, Tazeen H Jafar, Charles S Janipalli, Toby Johnson, Sekar Kathiresan, Kay-Tee Khaw, Hyung-Lae Kim, Sanjay Kinra, Yoshikuni Kita, Mika Kivimaki, Jaspal S Kooner, M J Kranthi Kumar, Diana Kuh, Smita R Kulkarni, Meena Kumari, Johanna Kuusisto, Tatiana Kuznetsova, Markku Laakso, Maris Laan, Jaana Laitinen, Edward G Lakatta, Carl D Langefeld, Martin G Larson, Mark Lathrop, Debbie A Lawlor, Robert W Lawrence, Jong-Young Lee, Nanette R Lee, Daniel Levy, Yali Li, Will T Longstreth, Jian'an Luan, Gavin Lucas, Barbara Ludwig, Massimo Mangino, K Radha Mani, Michael G Marmot, Francesco U S Mattace-Raso, Giuseppe Matullo, Wendy L McArdle, Colin A McKenzie, Thomas Meitinger, Olle Melander, Pierre Meneton, James F Meschia, Tetsuro Miki, Yuri Milaneschi, Karen L Mohlke, Vincent Mooser, Mario A Morken, Richard W Morris, Thomas H Mosley, Samer Najjar, Narisu Narisu, Christopher Newton-Cheh, Khanh-Dung Hoang Nguyen, Peter Nilsson, Fredrik Nyberg, Christopher J O'Donnell, Toshio Ogihara, Takayoshi Ohkubo, Tomonori Okamura, Rick Twee-Hee Ong, Halit Ongen, N Charlotte Onland-Moret, Paul F O'Reilly, Elin Org, Marco Orru, Walter Palmas, Jutta Palmen, Lyle J Palmer, Nicholette D Palmer, Alex N Parker, John F Peden, Leena Peltonen, Markus Perola, Vasyl Pihur, Carl G P Platou, Andrew Plump, Dorairajan Prabhakaran, Bruce M Psaty, Leslie J Raffel, Dabeeru C Rao, Asif Rasheed, Fulvio Ricceri, Kenneth M Rice, Annika Rosengren, Jerome I Rotter, Megan E Rudock, Siim Sõber, Tunde Salako, Danish Saleheen, Veikko Salomaa, Nilesh J Samani, Steven M Schwartz, Peter E H Schwarz, Laura J Scott, James Scott, Angelo Scuteri, Joban S Sehmi, Mark Seielstad, Sudha Seshadri, Pankaj Sharma, Sue Shaw-Hawkins, Gang Shi, Nick R G Shrine, Eric J G Sijbrands, Xueling Sim, Andrew Singleton, Marketa Sjögren, Nicholas L Smith, Maria Soler Artigas, Tim D Spector, Jan A Staessen, Alena Stancakova, Nanette I Steinle, David P Strachan, Heather M Stringham, Yan V Sun, Amy J Swift, Yasuharu Tabara, E-Shyong Tai, Philippa J Talmud, Andrew Taylor, Janos Terzic, Dag S Thelle, Martin D Tobin, Maciej Tomaszewski, Vikal Tripathy, Jaakko Tuomilehto, Ioanna Tzoulaki, Manuela Uda, Hirotsugu Ueshima, Cuno S P M Uiterwaal, Satoshi Umemura, Pim van der Harst, Yvonne T van der Schouw, Wiek H van Gilst, Erkki Vartiainen, Ramachandran S Vasan, Gudrun Veldre, Germaine C Verwoert, Margus Viigimaa, D G Vinay, Paolo Vineis, Benjamin F Voight, Peter Vollenweider, Lynne E Wagenknecht, Louise V Wain, Xiaoling Wang, Thomas J Wang, Nicholas J Wareham, Hugh Watkins, Alan B Weder, Peter H Whincup, Kerri L Wiggins, Jacqueline C M Witteman, Andrew Wong, Ying Wu, Chittaranjan S Yajnik, Jie Yao, J H Young, Diana Zelenika, Guangju Zhai, Weihua Zhang, Feng Zhang, Jing Hua Zhao, Haidong Zhu, Xiaofeng Zhu, Paavo Zitting, Ewa Zukowska-Szczechowska, Yukinori Okada, Jer-Yuarn Wu, Dongfeng Gu, Fumihiko Takeuchi, Atsushi Takahashi, Shiro Maeda, Tatsuhiko Tsunoda, Peng Chen, Su-Chi Lim, Tien-Yin Wong, Jianjun Liu, Terri L Young, Tin Aung, Yik-Ying Teo, Young Jin Kim, Daehee Kang, Chien-Hsiun Chen, Fuu-Jen Tsai, Li-Ching Chang, S-J Cathy Fann, Hao Mei, James E Hixson, Shufeng Chen, Tomohiro Katsuya, Masato Isono, Eva Albrecht, Kazuhiko Yamamoto, Michiaki Kubo, Yusuke Nakamura, Naoyuki Kamatani, Norihiro Kato, Jiang He, Yuan-Tsong Chen, Toshihiro Tanaka, Muredach P Reilly, Heribert Schunkert, Themistocles L Assimes, Alistair Hall, Christian Hengstenberg, Inke R König, Reijo Laaksonen, Ruth McPherson, John R Thompson, Unnur Thorsteinsdottir, Andreas Ziegler, Devin Absher, Li Chen, L Adrienne Cupples, Eran Halperin, Mingyao Li, Kiran Musunuru, Michael Preuss, Arne Schillert, Gudmar Thorleifsson, George A Wells, Hilma Holm, Robert Roberts, Alexandre F R Stewart, Stephen Fortmann, Alan Go, Mark Hlatky, Carlos Iribarren, Joshua Knowles, Richard Myers, Thomas Quertermous, Steven Sidney, Neil Risch, Hua Tang, Stefan Blankenberg, Renate Schnabel, Christoph Sinning, Karl J Lackner, Laurence Tiret, Viviane Nicaud, Francois Cambien, Christoph Bickel, Hans J Rupprecht, Claire Perret, Carole Proust, Thomas F Münzel, Maja Barbalic, Ida Yii-Der Chen, Serkalem Demissie-Banjaw, Aaron Folsom, Thomas Lumley, Kristin Marciante, Kent D Taylor, Kelly Volcik, Solveig Gretarsdottir, Jeffrey R Gulcher, Augustine Kong, Kari Stefansson, Gudmundur Thorgeirsson, Karl Andersen, Marcus Fischer, Anika Grosshennig, Patrick Linsel-Nitschke, Klaus Stark, Stefan Schreiber, Zouhair Aherrahrou, Petra Bruse, Angela Doering, Norman Klopp, Patrick Diemert, Christina Loley, Anja Medack, Janja Nahrstedt, Annette Peters, Arnika K Wagner, Christina Willenborg, Bernhard O Böhm, Harald Dobnig, Tanja B Grammer, Michael M Hoffmann, Andreas Meinitzer, Bernhard R Winkelmann, Stefan Pilz, Wilfried Renner, Hubert Scharnagl, Tatjana Stojakovic, Andreas Tomaschitz, Karl Winkler, Candace Guiducci, Noel Burtt, Stacey B Gabriel, Sonny Dandona, Olga Jarinova, Liming Qu, Robert Wilensky, William Matthai, Hakon H Hakonarson, Joe Devaney, Mary Susan Burnett, Augusto D Pichard, Kenneth M Kent, Lowell Satler, Joseph M Lindsay, Ron Waksman, Christopher W Knouff, Dawn M Waterworth, Max C Walker, Stephen E Epstein, Daniel J Rader, Christopher P Nelson, Benjamin J Wright, Anthony J Balmforth, Stephen G Ball, Laura R Loehr, Wayne D Rosamond, Emelia Benjamin, Talin Haritunians, David Couper, Joanne Murabito, Ying A Wang, Bruno H Stricker, Patricia P Chang, James T Willerson, Stephan B Felix, Norbert Watzinger, Jayashri Aragam, Robert Zweiker, Lars Lind, Richard J Rodeheffer, Karin Halina Greiser, Jaap W Deckers, Jan Stritzke, Erik Ingelsson, Iftikhar Kullo, Johannes Haerting, Thorsten Reffelmann, Margaret M Redfield, Karl Werdan, Gary F Mitchell, Donna K Arnett, John S Gottdiener, Maria Blettner, Nele Friedrich/titolo:Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function./doi:10.1038%2Fncomms10023/rivista:Nature communications/anno:2016/pagina_da:10023/pagina_a:/intervallo_pagine:10023/volume:7
Nature Communications
Pattaro, C, Teumer, A, Gorski, M, Chu, A Y, Li, M, Mijatovic, V, Garnaas, M, Tin, A, Sorice, R, Li, Y, Taliun, D, Olden, M, Foster, M, Yang, Q, Chen, M-H, Pers, T H, Johnson, A D, Ko, Y-A, Fuchsberger, C, Tayo, B, Nalls, M, Feitosa, M F, Isaacs, A, Dehghan, A, d'Adamo, P, Adeyemo, A, Dieffenbach, A K, Zonderman, A B, Nolte, I M, van der Most, P J, Wright, A F, Shuldiner, A R, Morrison, A C, Hofman, A, Smith, A V, Dreisbach, A W, Franke, A, Uitterlinden, A G, Metspalu, A, Tonjes, A, Lupo, A, Robino, A, Johansson, A, Demirkan, A, Kollerits, B, Freedman, B I, Ponte, B, Oostra, B A, Paulweber, B, Kraemer, B K, Mitchell, B D, Buckley, B M, Peralta, C A, Hayward, C, Helmer, C, Rotimi, C N, Shaffer, C M, Mueller, C, Sala, C, van Duijn, C M, Saint-Pierre, A, Ackermann, D, Shriner, D, Ruggiero, D, Toniolo, D, Lu, Y, Cusi, D, Czamara, D, Ellinghaus, D, Siscovick, D S, Ruderfer, D, Gieger, C, Grallert, H, Rochtchina, E, Atkinson, E J, Holliday, E G, Boerwinkle, E, Salvi, E, Bottinger, E P, Murgia, F, Rivadeneira, F, Ernst, F, Kronenberg, F, Hu, F B, Navis, G J, Curhan, G C, Ehret, G B, Homuth, G, Coassin, S, Thun, G-A, Pistis, G, Gambaro, G, Malerba, G, Montgomery, G W, Eiriksdottir, G, Jacobs, G, Li, G, Wichmann, H-E, Campbell, H, Schmidt, H, Wallaschofski, H, Voelzke, H, Brenner, H, Kroemer, H K, Kramer, H, Lin, H, Leach, I M, Ford, I, Guessous, I, Rudan, I, Prokopenko, I, Borecki, I, Heid, I M, Kolcic, I, Persico, I, Jukema, J W, Wilson, J F, Felix, J F, Divers, J, Lambert, J-C, Stafford, J M, Gaspoz, J-M, Smith, J A, Faul, J D, Wang, J J, Ding, J, Hirschhorn, J N, Attia, J, Whitfield, J B, Chalmers, J, Viikari, J, Coresh, J, Denny, J C, Karjalainen, J, Fernandes, J K, Endlich, K, Butterbach, K, Keene, K L, Lohman, K, Portas, L, Launer, L J, Lyytikaeinen, L-P, Yengo, L, Franke, L, Ferrucci, L, Rose, L M, Kedenko, L, Rao, M, Struchalin, M, Kleber, M E, Cavalieri, M, Haun, M, Cornelis, M C, Ciullo, M, Pirastu, M, de Andrade, M, McEvoy, M A, Woodward, M, Adam, M, Cocca, M, Nauck, M, Imboden, M, Waldenberger, M, Pruijm, M, Metzger, M, Stumvoll, M, Evans, M K, Sale, M M, Kaehoenen, M, Boban, M, Bochud, M, Rheinberger, M, Verweij, N, Bouatia-Naji, N, Martin, N G, Hastie, N, Probst-Hensch, N, Soranzo, N, Devuyst, O, Raitakari, O, Gottesman, O, Franco, O H, Polasek, O, Gasparini, P, Munroe, P B, Ridker, P M, Mitchell, P, Muntner, P, Meisinger, C, Smit, J H, Kovacs, P, Wild, P S, Froguel, P, Rettig, R, Maegi, R, Biffar, R, Schmidt, R, Middelberg, R P S, Carroll, R J, Penninx, B W, Scott, R J, Katz, R, Sedaghat, S, Wild, S H, Kardia, S L R, Ulivi, S, Hwang, S-J, Enroth, S, Kloiber, S, Trompet, S, Stengel, B, Hancock, S J, Turner, S T, Rosas, S E, Stracke, S, Harris, T B, Zeller, T, Zemunik, T, Lehtimaeki, T, Illig, T, Aspelund, T, Nikopensius, T, Esko, T, Tanaka, T, Gyllensten, U, Voelker, U, Emilsson, V, Vitart, V, Aalto, V, Gudnason, V, Chouraki, V, Chen, W-M, Igl, W, Maerz, W, Koenig, W, Lieb, W, Loos, R J F, Liu, Y, Snieder, H, Pramstaller, P P, Parsa, A, O'Connell, J R, Susztak, K, Hamet, P, Tremblay, J, de Boer, I H, Boeger, C A, Goessling, W, Chasman, D I, Koettgen, A, Kao, W H L & Fox, C S 2016, ' Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function ', Nature Communications, vol. 7 . https://doi.org/10.1038/ncomms10023
Nature Communications [E], 7. Nature Publishing Group
Nature Communications, Vol. 7 (2016) P. 10023
Nature Communications, 7:10023. Nature Publishing Group
Nature Communications, 7(10023). Nature Publishing Group
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; ... (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications, 7, p. 10023. Nature Publishing Group 10.1038/ncomms10023
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Nature Communications, vol. 7, pp. 10023
NATURE COMMUNICATIONS
Pattaro, C, Teumer, A, Gorski, M, Chu, A Y, Li, M, Mijatovic, V, Garnaas, M, Tin, A, Sorice, R, Li, Y, Taliun, D, Olden, M, Foster, M, Yang, Q, Chen, M-H, Pers, T H, Johnson, A D, Ko, Y-A, Fuchsberger, C, Tayo, B, Nalls, M, Feitosa, M F, Isaacs, A, Dehghan, A, d'Adamo, P, Adeyemo, A, Dieffenbach, A K, Zonderman, A B, Nolte, I M, van der Most, P J, Wright, A F, Shuldiner, A R, Morrison, A C, Hofman, A, Smith, A V, Dreisbach, A W, Franke, A, Uitterlinden, A G, Metspalu, A, Tonjes, A, Hayward, C, Campbell, H, Rudan, I, Wilson, J F, Martin, N G, Hastie, N, Polasek, O, Mitchell, P & Wild, S H & Vitart, V 2016, ' Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function ', Nature Communications, vol. 7, 10023 . https://doi.org/10.1038/ncomms10023
Nature Communications, 7
Nature Communications, 7. Nature Publishing Group
Nature communications 7 (2016): 10023. doi:10.1038/ncomms10023
info:cnr-pdr/source/autori:Cristian Pattaro 1, Alexander Teumer 2 3, Mathias Gorski 4 5, Audrey Y Chu 6, Man Li 7, Vladan Mijatovic 8, Maija Garnaas 9, Adrienne Tin 7, Rossella Sorice 10, Yong Li 11, Daniel Taliun 1, Matthias Olden 4 5, Meredith Foster 12, Qiong Yang 13, Ming-Huei Chen 13 14, Tune H Pers 15 16, Andrew D Johnson 17, Yi-An Ko 18, Christian Fuchsberger 1, Bamidele Tayo 19, Michael Nalls 20, Mary F Feitosa 21, Aaron Isaacs 22 23, Abbas Dehghan 24, Pio d'Adamo 25, Adebowale Adeyemo 26, Aida Karina Dieffenbach 27 28, Alan B Zonderman 29, Ilja M Nolte 30, Peter J van der Most 30, Alan F Wright 31, Alan R Shuldiner 32 33, Alanna C Morrison 34, Albert Hofman 24, Albert V Smith 35 36, Albert W Dreisbach 37, Andre Franke 38, Andre G Uitterlinden 39, Andres Metspalu 40 41, Anke Tonjes 42, Antonio Lupo 43, Antonietta Robino 25, Åsa Johansson 44, Ayse Demirkan 22, Barbara Kollerits 45, Barry I Freedman 46, Belen Ponte 47, Ben A Oostra 48, Bernhard Paulweber 49, Bernhard K Krämer 50, Braxton D Mitchell 32 33, Brendan M Buckley 51, Carmen A Peralta 52, Caroline Hayward 31, Catherine Helmer 53 54, Charles N Rotimi 26, Christian M Shaffer 55, Christian Müller 56 57, Cinzia Sala 58, Cornelia M van Duijn 22, Aude Saint-Pierre 1 59, Daniel Ackermann 47, Daniel Shriner 26, Daniela Ruggiero 10, Daniela Toniolo 58 60, Yingchang Lu 61, Daniele Cusi 62, Darina Czamara 63, David Ellinghaus 38, David S Siscovick 64, Douglas Ruderfer 65, Christian Gieger 66, Harald Grallert 67 68 69, Elena Rochtchina 70, Elizabeth J Atkinson 71, Elizabeth G Holliday 72 73, Eric Boerwinkle 34, Erika Salvi 62, Erwin P Bottinger 61, Federico Murgia 74, Fernando Rivadeneira 39, Florian Ernst 2, Florian Kronenberg 45, Frank B Hu 75, Gerjan J Navis 76, Gary C Curhan 77, George B Ehret 78, Georg Homuth 2, Stefan Coassin 45, Gian-Andri Thun 79 80, Giorgio Pistis 58, Giovanni Gambaro 81, Giovanni Malerba 8, Grant W Montgomery 82, Gudny Eiriksdottir 35, Gunnar Jacobs 83, Guo Li 64, H-Erich Wichmann 84 85 86, Harry Campbell 87, Helena Schmidt 88, Henri Wallaschofski 89 90, Henry Völzke 3 90, Hermann Brenner 27 28, Heyo K Kroemer 91, Holly Kramer 19, Honghuang Lin 92, I Mateo Leach 93, Ian Ford 94, Idris Guessous 95 96 97, Igor Rudan 87, Inga Prokopenko 98, Ingrid Borecki 21, Iris M Heid 4 66, Ivana Kolcic 99, Ivana Persico 74, J Wouter Jukema 100 101 102 103, James F Wilson 87, Janine F Felix 24, Jasmin Divers 104, Jean-Charles Lambert 105, Jeanette M Stafford 104, Jean-Michel Gaspoz 95, Jennifer A Smith 106, Jessica D Faul 107, Jie Jin Wang 108, Jingzhong Ding 109, Joel N Hirschhorn 15 16 110, John Attia 71 72, John B Whitfield 82, John Chalmers 111, Jorma Viikari 112, Josef Coresh 7 113, Joshua C Denny 114, Juha Karjalainen 115, Jyotika K Fernandes 116, Karlhans Endlich 117, Katja Butterbach 27, Keith L Keene 118, Kurt Lohman 46, Laura Portas 74, Lenore J Launer 119, Leo-Pekka Lyytikäinen 120, Loic Yengo 121 122 123, Lude Franke 115, Luigi Ferrucci 124, Lynda M Rose 6, Lyudmyla Kedenko 49, Madhumathi Rao 12, Maksim Struchalin 125 126, Marcus E Kleber 127, Margherita Cavalieri 128, Margot Haun 45, Marilyn C Cornelis 75, Marina Ciullo 10, Mario Pirastu 74, Mariza de Andrade 71, Mark A McEvoy 129, Mark Woodward 7 111 112 130, Martin Adam 79 80, Massimiliano Cocca 58, Matthias Nauck 89 90, Medea Imboden 79 80, Melanie Waldenberger 67, Menno Pruijm 131, Marie Metzger 132, Michael Stumvoll 42, Michele K Evans 133, Michele M Sale 134, Mika Kähönen 135, Mladen Boban 99, Murielle Bochud 136, Myriam Rheinberger 5, Niek Verweij 93, Nabila Bouatia-Naji 137 138, Nicholas G Martin 82 139, Nick Hastie 31, Nicole Probst-Hensch 79 80, Nicole Soranzo 140, Olivier Devuyst 141, Olli Raitakari 142, Omri Gottesman 61, Oscar H Franco 24, Ozren Polasek 99, Paolo Gasparini 25, Patricia B Munroe 143 144, Paul M Ridker 145, Paul Mitchell 108, Paul Muntner 146 147, Christa Meisinger 68, Johannes H Smit 148, ICBP Consortium; AGEN Consortium; CARDIOGRAM; CHARGe-Heart Failure Group; ECHOGen Consortium; Peter Kovacs 149, Philipp S Wild 150, Philippe Froguel 121 122 123, Rainer Rettig 151, Reedik Mägi 40, Reiner Biffar 152, Reinhold Schmidt 128, Rita P S Middelberg 82, Robert J Carroll 114, Brenda W Penninx 148, Rodney J Scott 153, Ronit Katz 154, Sanaz Sedaghat 24, Sarah H Wild 87, Sharon L R Kardia 106, Sheila Ulivi 155, Shih-Jen Hwang 17, Stefan Enroth 44, Stefan Kloiber 63, Stella Trompet 100, Benedicte Stengel 132, Stephen J Hancock 72 73, Stephen T Turner 156, Sylvia E Rosas 18, Sylvia Stracke 105 157, Tamara B Harris 119, Tanja Zeller 56 57, Tatijana Zemunik 99, Terho Lehtimäki 120, Thomas Illig 68, Thor Aspelund 35 36, Tiit Nikopensius 40 41, Tonu Esko 15 40 41, Toshiko Tanaka 124, Ulf Gyllensten 44, Uwe Völker 2 90, Valur Emilsson 35 158, Veronique Vitart 31, Ville Aalto 159, Vilmundur Gudnason 35 36, Vincent Chouraki 105, Wei-Min Chen 134, Wilmar Igl 44, Winfried März 160, Wolfgang Koenig 161, Wolfgang Lieb 83, Ruth J F Loos 61 162, Yongmei Liu 46, Harold Snieder 30, Peter P Pramstaller 1 163 164, Afshin Parsa 165, Jeffrey R O'Connell 32, Katalin Susztak 18, Pavel Hamet 166, Johanne Tremblay 166, Ian H de Boer 154, Carsten A Böger 5, Wolfram Goessling 9, Daniel I Chasman 6 145, Anna Köttgen 7 11, W H Linda Kao 7 113, Caroline S Fox 17 167. Collaborators: Goncalo R Abecasis, Linda S Adair, Myriam Alexander, David Altshuler, Najaf Amin, Dan E Arking, Pankaj Arora, Yurii Aulchenko, Stephan J L Bakker, Stefania Bandinelli, Ines Barroso, Jacques S Beckmann, John P Beilby, Richard N Bergman, Sven Bergmann, Joshua C Bis, Michael Boehnke, Lori L Bonnycastle, Stefan R Bornstein, Michiel L Bots, Jennifer L Bragg-Gresham, Stefan-Martin Brand, Eva Brand, Peter S Braund, Morris J Brown, Paul R Burton, Juan P Casas, Mark J Caulfield, Aravinda Chakravarti, John C Chambers, Giriraj R Chandak, Yen-Pei C Chang, Fadi J Charchar, Nish Chaturvedi, Yoon Shin Cho, Robert Clarke, Francis S Collins, Rory Collins, John M Connell, Jackie A Cooper, Matthew N Cooper, Richard S Cooper, Anna Maria Corsi, Marcus Dörr, Santosh Dahgam, John Danesh, George Davey Smith, Ian N M Day, Panos Deloukas, Matthew Denniff, Anna F Dominiczak, Yanbin Dong, Ayo Doumatey, Paul Elliott, Roberto Elosua, Jeanette Erdmann, Susana Eyheramendy, Martin Farrall, Cristiano Fava, Terrence Forrester, F Gerald R Fowkes, Ervin R Fox, Timothy M Frayling, Pilar Galan, Santhi K Ganesh, Melissa Garcia, Tom R Gaunt, Nicole L Glazer, Min Jin Go, Anuj Goel, Jürgen Grässler, Diederick E Grobbee, Leif Groop, Simonetta Guarrera, Xiuqing Guo, David Hadley, Anders Hamsten, Bok-Ghee Han, Rebecca Hardy, Anna-Liisa Hartikainen, Simon Heath, Susan R Heckbert, Bo Hedblad, Serge Hercberg, Dena Hernandez, Andrew A Hicks, Gina Hilton, Aroon D Hingorani, Judith A Hoffman Bolton, Jemma C Hopewell, Philip Howard, Steve E Humphries, Steven C Hunt, Kristian Hveem, M Arfan Ikram, Muhammad Islam, Naoharu Iwai, Marjo-Riitta Jarvelin, Anne U Jackson, Tazeen H Jafar, Charles S Janipalli, Toby Johnson, Sekar Kathiresan, Kay-Tee Khaw, Hyung-Lae Kim, Sanjay Kinra, Yoshikuni Kita, Mika Kivimaki, Jaspal S Kooner, M J Kranthi Kumar, Diana Kuh, Smita R Kulkarni, Meena Kumari, Johanna Kuusisto, Tatiana Kuznetsova, Markku Laakso, Maris Laan, Jaana Laitinen, Edward G Lakatta, Carl D Langefeld, Martin G Larson, Mark Lathrop, Debbie A Lawlor, Robert W Lawrence, Jong-Young Lee, Nanette R Lee, Daniel Levy, Yali Li, Will T Longstreth, Jian'an Luan, Gavin Lucas, Barbara Ludwig, Massimo Mangino, K Radha Mani, Michael G Marmot, Francesco U S Mattace-Raso, Giuseppe Matullo, Wendy L McArdle, Colin A McKenzie, Thomas Meitinger, Olle Melander, Pierre Meneton, James F Meschia, Tetsuro Miki, Yuri Milaneschi, Karen L Mohlke, Vincent Mooser, Mario A Morken, Richard W Morris, Thomas H Mosley, Samer Najjar, Narisu Narisu, Christopher Newton-Cheh, Khanh-Dung Hoang Nguyen, Peter Nilsson, Fredrik Nyberg, Christopher J O'Donnell, Toshio Ogihara, Takayoshi Ohkubo, Tomonori Okamura, Rick Twee-Hee Ong, Halit Ongen, N Charlotte Onland-Moret, Paul F O'Reilly, Elin Org, Marco Orru, Walter Palmas, Jutta Palmen, Lyle J Palmer, Nicholette D Palmer, Alex N Parker, John F Peden, Leena Peltonen, Markus Perola, Vasyl Pihur, Carl G P Platou, Andrew Plump, Dorairajan Prabhakaran, Bruce M Psaty, Leslie J Raffel, Dabeeru C Rao, Asif Rasheed, Fulvio Ricceri, Kenneth M Rice, Annika Rosengren, Jerome I Rotter, Megan E Rudock, Siim Sõber, Tunde Salako, Danish Saleheen, Veikko Salomaa, Nilesh J Samani, Steven M Schwartz, Peter E H Schwarz, Laura J Scott, James Scott, Angelo Scuteri, Joban S Sehmi, Mark Seielstad, Sudha Seshadri, Pankaj Sharma, Sue Shaw-Hawkins, Gang Shi, Nick R G Shrine, Eric J G Sijbrands, Xueling Sim, Andrew Singleton, Marketa Sjögren, Nicholas L Smith, Maria Soler Artigas, Tim D Spector, Jan A Staessen, Alena Stancakova, Nanette I Steinle, David P Strachan, Heather M Stringham, Yan V Sun, Amy J Swift, Yasuharu Tabara, E-Shyong Tai, Philippa J Talmud, Andrew Taylor, Janos Terzic, Dag S Thelle, Martin D Tobin, Maciej Tomaszewski, Vikal Tripathy, Jaakko Tuomilehto, Ioanna Tzoulaki, Manuela Uda, Hirotsugu Ueshima, Cuno S P M Uiterwaal, Satoshi Umemura, Pim van der Harst, Yvonne T van der Schouw, Wiek H van Gilst, Erkki Vartiainen, Ramachandran S Vasan, Gudrun Veldre, Germaine C Verwoert, Margus Viigimaa, D G Vinay, Paolo Vineis, Benjamin F Voight, Peter Vollenweider, Lynne E Wagenknecht, Louise V Wain, Xiaoling Wang, Thomas J Wang, Nicholas J Wareham, Hugh Watkins, Alan B Weder, Peter H Whincup, Kerri L Wiggins, Jacqueline C M Witteman, Andrew Wong, Ying Wu, Chittaranjan S Yajnik, Jie Yao, J H Young, Diana Zelenika, Guangju Zhai, Weihua Zhang, Feng Zhang, Jing Hua Zhao, Haidong Zhu, Xiaofeng Zhu, Paavo Zitting, Ewa Zukowska-Szczechowska, Yukinori Okada, Jer-Yuarn Wu, Dongfeng Gu, Fumihiko Takeuchi, Atsushi Takahashi, Shiro Maeda, Tatsuhiko Tsunoda, Peng Chen, Su-Chi Lim, Tien-Yin Wong, Jianjun Liu, Terri L Young, Tin Aung, Yik-Ying Teo, Young Jin Kim, Daehee Kang, Chien-Hsiun Chen, Fuu-Jen Tsai, Li-Ching Chang, S-J Cathy Fann, Hao Mei, James E Hixson, Shufeng Chen, Tomohiro Katsuya, Masato Isono, Eva Albrecht, Kazuhiko Yamamoto, Michiaki Kubo, Yusuke Nakamura, Naoyuki Kamatani, Norihiro Kato, Jiang He, Yuan-Tsong Chen, Toshihiro Tanaka, Muredach P Reilly, Heribert Schunkert, Themistocles L Assimes, Alistair Hall, Christian Hengstenberg, Inke R König, Reijo Laaksonen, Ruth McPherson, John R Thompson, Unnur Thorsteinsdottir, Andreas Ziegler, Devin Absher, Li Chen, L Adrienne Cupples, Eran Halperin, Mingyao Li, Kiran Musunuru, Michael Preuss, Arne Schillert, Gudmar Thorleifsson, George A Wells, Hilma Holm, Robert Roberts, Alexandre F R Stewart, Stephen Fortmann, Alan Go, Mark Hlatky, Carlos Iribarren, Joshua Knowles, Richard Myers, Thomas Quertermous, Steven Sidney, Neil Risch, Hua Tang, Stefan Blankenberg, Renate Schnabel, Christoph Sinning, Karl J Lackner, Laurence Tiret, Viviane Nicaud, Francois Cambien, Christoph Bickel, Hans J Rupprecht, Claire Perret, Carole Proust, Thomas F Münzel, Maja Barbalic, Ida Yii-Der Chen, Serkalem Demissie-Banjaw, Aaron Folsom, Thomas Lumley, Kristin Marciante, Kent D Taylor, Kelly Volcik, Solveig Gretarsdottir, Jeffrey R Gulcher, Augustine Kong, Kari Stefansson, Gudmundur Thorgeirsson, Karl Andersen, Marcus Fischer, Anika Grosshennig, Patrick Linsel-Nitschke, Klaus Stark, Stefan Schreiber, Zouhair Aherrahrou, Petra Bruse, Angela Doering, Norman Klopp, Patrick Diemert, Christina Loley, Anja Medack, Janja Nahrstedt, Annette Peters, Arnika K Wagner, Christina Willenborg, Bernhard O Böhm, Harald Dobnig, Tanja B Grammer, Michael M Hoffmann, Andreas Meinitzer, Bernhard R Winkelmann, Stefan Pilz, Wilfried Renner, Hubert Scharnagl, Tatjana Stojakovic, Andreas Tomaschitz, Karl Winkler, Candace Guiducci, Noel Burtt, Stacey B Gabriel, Sonny Dandona, Olga Jarinova, Liming Qu, Robert Wilensky, William Matthai, Hakon H Hakonarson, Joe Devaney, Mary Susan Burnett, Augusto D Pichard, Kenneth M Kent, Lowell Satler, Joseph M Lindsay, Ron Waksman, Christopher W Knouff, Dawn M Waterworth, Max C Walker, Stephen E Epstein, Daniel J Rader, Christopher P Nelson, Benjamin J Wright, Anthony J Balmforth, Stephen G Ball, Laura R Loehr, Wayne D Rosamond, Emelia Benjamin, Talin Haritunians, David Couper, Joanne Murabito, Ying A Wang, Bruno H Stricker, Patricia P Chang, James T Willerson, Stephan B Felix, Norbert Watzinger, Jayashri Aragam, Robert Zweiker, Lars Lind, Richard J Rodeheffer, Karin Halina Greiser, Jaap W Deckers, Jan Stritzke, Erik Ingelsson, Iftikhar Kullo, Johannes Haerting, Thorsten Reffelmann, Margaret M Redfield, Karl Werdan, Gary F Mitchell, Donna K Arnett, John S Gottdiener, Maria Blettner, Nele Friedrich/titolo:Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function./doi:10.1038%2Fncomms10023/rivista:Nature communications/anno:2016/pagina_da:10023/pagina_a:/intervallo_pagine:10023/volume:7
Nature Communications
Pattaro, C, Teumer, A, Gorski, M, Chu, A Y, Li, M, Mijatovic, V, Garnaas, M, Tin, A, Sorice, R, Li, Y, Taliun, D, Olden, M, Foster, M, Yang, Q, Chen, M-H, Pers, T H, Johnson, A D, Ko, Y-A, Fuchsberger, C, Tayo, B, Nalls, M, Feitosa, M F, Isaacs, A, Dehghan, A, d'Adamo, P, Adeyemo, A, Dieffenbach, A K, Zonderman, A B, Nolte, I M, van der Most, P J, Wright, A F, Shuldiner, A R, Morrison, A C, Hofman, A, Smith, A V, Dreisbach, A W, Franke, A, Uitterlinden, A G, Metspalu, A, Tonjes, A, Lupo, A, Robino, A, Johansson, A, Demirkan, A, Kollerits, B, Freedman, B I, Ponte, B, Oostra, B A, Paulweber, B, Kraemer, B K, Mitchell, B D, Buckley, B M, Peralta, C A, Hayward, C, Helmer, C, Rotimi, C N, Shaffer, C M, Mueller, C, Sala, C, van Duijn, C M, Saint-Pierre, A, Ackermann, D, Shriner, D, Ruggiero, D, Toniolo, D, Lu, Y, Cusi, D, Czamara, D, Ellinghaus, D, Siscovick, D S, Ruderfer, D, Gieger, C, Grallert, H, Rochtchina, E, Atkinson, E J, Holliday, E G, Boerwinkle, E, Salvi, E, Bottinger, E P, Murgia, F, Rivadeneira, F, Ernst, F, Kronenberg, F, Hu, F B, Navis, G J, Curhan, G C, Ehret, G B, Homuth, G, Coassin, S, Thun, G-A, Pistis, G, Gambaro, G, Malerba, G, Montgomery, G W, Eiriksdottir, G, Jacobs, G, Li, G, Wichmann, H-E, Campbell, H, Schmidt, H, Wallaschofski, H, Voelzke, H, Brenner, H, Kroemer, H K, Kramer, H, Lin, H, Leach, I M, Ford, I, Guessous, I, Rudan, I, Prokopenko, I, Borecki, I, Heid, I M, Kolcic, I, Persico, I, Jukema, J W, Wilson, J F, Felix, J F, Divers, J, Lambert, J-C, Stafford, J M, Gaspoz, J-M, Smith, J A, Faul, J D, Wang, J J, Ding, J, Hirschhorn, J N, Attia, J, Whitfield, J B, Chalmers, J, Viikari, J, Coresh, J, Denny, J C, Karjalainen, J, Fernandes, J K, Endlich, K, Butterbach, K, Keene, K L, Lohman, K, Portas, L, Launer, L J, Lyytikaeinen, L-P, Yengo, L, Franke, L, Ferrucci, L, Rose, L M, Kedenko, L, Rao, M, Struchalin, M, Kleber, M E, Cavalieri, M, Haun, M, Cornelis, M C, Ciullo, M, Pirastu, M, de Andrade, M, McEvoy, M A, Woodward, M, Adam, M, Cocca, M, Nauck, M, Imboden, M, Waldenberger, M, Pruijm, M, Metzger, M, Stumvoll, M, Evans, M K, Sale, M M, Kaehoenen, M, Boban, M, Bochud, M, Rheinberger, M, Verweij, N, Bouatia-Naji, N, Martin, N G, Hastie, N, Probst-Hensch, N, Soranzo, N, Devuyst, O, Raitakari, O, Gottesman, O, Franco, O H, Polasek, O, Gasparini, P, Munroe, P B, Ridker, P M, Mitchell, P, Muntner, P, Meisinger, C, Smit, J H, Kovacs, P, Wild, P S, Froguel, P, Rettig, R, Maegi, R, Biffar, R, Schmidt, R, Middelberg, R P S, Carroll, R J, Penninx, B W, Scott, R J, Katz, R, Sedaghat, S, Wild, S H, Kardia, S L R, Ulivi, S, Hwang, S-J, Enroth, S, Kloiber, S, Trompet, S, Stengel, B, Hancock, S J, Turner, S T, Rosas, S E, Stracke, S, Harris, T B, Zeller, T, Zemunik, T, Lehtimaeki, T, Illig, T, Aspelund, T, Nikopensius, T, Esko, T, Tanaka, T, Gyllensten, U, Voelker, U, Emilsson, V, Vitart, V, Aalto, V, Gudnason, V, Chouraki, V, Chen, W-M, Igl, W, Maerz, W, Koenig, W, Lieb, W, Loos, R J F, Liu, Y, Snieder, H, Pramstaller, P P, Parsa, A, O'Connell, J R, Susztak, K, Hamet, P, Tremblay, J, de Boer, I H, Boeger, C A, Goessling, W, Chasman, D I, Koettgen, A, Kao, W H L & Fox, C S 2016, ' Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function ', Nature Communications, vol. 7 . https://doi.org/10.1038/ncomms10023
Nature Communications [E], 7. Nature Publishing Group
Nature Communications, Vol. 7 (2016) P. 10023
Nature Communications, 7:10023. Nature Publishing Group
Nature Communications, 7(10023). Nature Publishing Group
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; ... (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications, 7, p. 10023. Nature Publishing Group 10.1038/ncomms10023
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Nature Communications, vol. 7, pp. 10023
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combinin
Externí odkaz:
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https://doi.org/10.1038/ncomms10023
https://doi.org/10.1038/ncomms10023
Autor:
Locke, Adam E, Kahali, Bratati, Croteau-Chonka, Damien C, Doney, Alex S F, He, Bing, Heikkilä, Outi, Hietala, Kustaa, Kytö, Janne, Lahermo, Päivi, Lehto, Markku, Österholm, Anne-May, Parkkonen, Maija, Pitkäniemi, Janne, Rosengård-Bärlund, Milla, Eklund, Niina, Saraheimo, Markku, Sarti, Cinzia, Söderlund, Jenny, Soro-Paavonen, Aino, Syreeni, Anna, Thorn, Lena M, Tikkanen, Heikki, Tolonen, Nina, Tryggvason, Karl, Tuomilehto, Jaakko, Estrada, Karol, Wadén, Johan, Gill, Geoffrey V, Prior, Sarah, Guiducci, Candace, Mirel, Daniel B, Taylor, Andrew, Hosseini, Mohsen, Parving, Hans-Henrik, Rossing, Peter, Tarnow, Lise, Eury, Elodie, Ladenvall, Claes, Alhenc-Gelas, François, Lefebvre, Pierre, Rigalleau, Vincent, Roussel, Ronan, Tregouet, David-Alexandre, Maestroni, Anna, Maestroni, Silvia, Falhammar, Henrik, Gu, Tianwei, Folkersen, Lasse, Möllsten, Anna, Cimponeriu, Dan, Mihai, Ioana, Mota, Maria, Mota, Eugen, Serafinceanu, Cristian, Stavarachi, Monica, Hanson, Robert L, Nelson, Robert G, Kretzler, Matthias, Fraser, Ross M, Colhoun, Helen M, Panduru, Nicolae Mircea, Gu, Harvest F, Brismar, Kerstin, Zerbini, Gianpaolo, Hadjadj, Samy, Marre, Michel, Groop, Leif, Lajer, Maria, Bull, Shelley B, Garcia, Melissa E, Waggott, Daryl, Paterson, Andrew D, Savage, David A, Bain, Stephen C, Martin, Finian, Hirschhorn, Joel N, Godson, Catherine, Florez, Jose C, Groop, Per-Henrik, Maxwell, Alexander P, Geller, Frank, Willer, Cristen J, Schmidt, Ellen M, Sengupta, Sebanti, Peloso, Gina M, Gustafsson, Stefan, Kanoni, Stavroula, Ganna, Andrea, Chen, Jin, Buchkovich, Martin L, Mora, Samia, Giedraitis, Vilmantas, Beckmann, Jacques S, Bragg-Gresham, Jennifer L, Chang, Hsing-Y, Demirkan, Ayşe, Den Hertog, Heleen M, Do, Ron, Donnelly, Louise A, Ehret, Georg B, Esko, Tõnu, Feitosa, Mary F, Gigante, Bruna, Ferreira, Teresa, Fischer, Krista, Fontanillas, Pierre, Freitag, Daniel F, Gurdasani, Deepti, Heikkilä, Kauko, Hyppönen, Elina, Isaacs, Aaron, Jackson, Anne U, Esko, Tonu, Go, Alan S, 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Publikováno v:
Nature, 518(7538), 197-206. Nature Publishing Group
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Nature, 518(7538), 197. Nature Publishing Group
Nature
Nature, 518(7538), 197-U401
Nature, Vol. 518, No 7538 (2015) pp. 197-206
Nature, vol. 518, no. 7538, pp. 197-206
Nature 518(7538), 197-206 (2015). doi:10.1038/nature14177
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Locke, A E, Kahali, B, Berndt, S I, Justice, A E, Pers, T H, Day, F R, Powell, C, Vedantam, S, Buchkovich, M L, Yang, J, Croteau-Chonka, D C, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, J C, Winkler, T W, Wood, A R, Workalemahu, T, Faul, J D, Smith, J A, Zhao, J H, Zhao, W, Chen, J, Fehrmann, R, Hedman, A K, Karjalainen, J, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M & Bolton, J L & Bragg-Gresham, L & Buyske, S & Demirkan, A & Deng, G & Fraser, R M & Hayward, C & McLachlan, S & Campbell, H & Morris, A D & Price, J F & Rudan, I & Walker, M & Wilson, J F & Visscher, P M 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-U401 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197-U401. Nature Publishing Group
Nature, 518, 7538, pp. 197-206
Nature, 518, 197-206
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Lifton, R P, Ma, B, McCarroll, S A, McKnight, A J, Min, J L, Moffatt, M F, Montgomery, G W, Murabito, J M, Nicholson, G, Nyholt, DR, Okada, Y, Perry, J R B, Dorajoo, R, Reinmaa, E, Salem, R M, Sandholm, N, Scott, R A, Stolk, L, Takahashi, A, Tanaka, T, van 't Hooft, F M, Vinkhuyzen, A A E, Westra, H, Zheng, W, Zondervan, K T, Heath, A C, Arveiler, D, Bakker, S J L, Beilby, J, Bergman, R N, Blangero, J, Bovet, P, Campbell, H, Caulfield, M J, Cesana, G, Chakravarti, A, Chasman, D I, Chines, P S, Collins, F S, Crawford, D C, Cupples, L A, Cusi, D, Danesh, J, de Faire, U, den Ruijter, H M, Dominiczak, A F, Erbel, R, Erdmann, J, Eriksson, J G, Farrall, M, Felix, S B, Ferrannini, E, Ferrieres, J, Ford, I, Forouhi, N G, Forrester, T, Franco, O H, Gansevoort, R T, Gejman, P V, Gieger, C, Gottesman, O, Gudnason, V, Gyllensten, U, Hall, A S, Harris, T B, Hattersley, A T, Hicks, A A, Hindorff, L A, Hingorani, A D, Hofman, A, Homuth, G, Hovingh, G K, Humphries, S E, Hunt, S C, Hypponen, E, Illig, T, Jacobs, K B, Jarvelin, M, Joeckel, K, Johansen, B, Jousilahti, P, Jukema, J W, Jula, A M, Kaprio, J, Kastelein, J J P, Keinanen-Kiukaanniemi, S M, Kiemeney, L A, Knekt, P, Kooner, J S, Kooperberg, C, Kovacs, P, Kraja, A T, Kumari, M, Kuusisto, J, Lakka, T A, Langenberg, C, Le Marchand, L, Lehtimaki, T, Lyssenko, V, Mannisto, S, Marette, A, Matise, T C, McKenzie, C A, McKnight, B, Moll, F L, Morris, A D, Morris, A P, Murray, J C, Nelis, M, Ohlsson, C, Oldehinkel, A J, Ong, K K, Madden, P A F, Pasterkamp, G, Peden, J F, Peters, A, Postma, D S, Pramstaller, P P, Price, J F, Qi, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Ridker, P M, Rioux, J D, Ritchie, M D, Rudan, I, Salomaa, V, Samani, N J, Saramines, J, Sarzynski, M A, Schunkert, H, Schwarz, P E H, Sever, P, Shuldiner, A R, Sinisalo, J, Stolk, R P, Strauch, K, Toenjes, A, Tregouet, D, Tremblay, A, Tremoli, E, Virtamo, J, Vohl, M, Voelker, U, Waeber, G, Willemsen, G, Witteman, J C, Zillikens, M C, Adair, L S, Amouyel, P, Asselbergs, F W, Assimes, T L, Bochud, M, Boehm, B O, Boerwinkle, E, Bornstein, S R, Bottinger, E P, Bouchard, C, Cauchi, S, Chambers, J C, Chanock, S J, Cooper, R S, de Bakker, P I W, Dedoussis, G, Ferrucci, L, Franks, P W, Froguel, P, Groop, L C, Haiman, C A, Hamsten, A, Hui, J, Hunter, D J, Hveem, K, Kaplan, R C, Kivimaki, M, Kuh, D, Laakso, M, Liu, Y, Martin, N G, Maerz, W, Melbve, M, Metspalu, A, Moebus, S, Munroe, P B, Njolstad, I, Oostra, B A, Palmer, C N A, Pedersen, N L, Perola, M, Perusse, L, Peters, U, Power, C, Quertermous, T, Rauramaa, R, Rivadeneira, F, Saaristo, T E, Saleheen, D, Sattar, N, Schadt, E E, Schlessinger, D, Slagboom, P E, Snieder, H, Spector, T D, Thorsteinsdottir, U R, Stumvoll, M, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van der Harst, P, Walker, M, Wallaschofski, H, Wareham, N J, Watkins, H, Weir, D R, Wichmann, H, Wilson, J F, Zanen, P, Borecki, I B, Deloukas, P, Fox, C S, Heid, I M, O'Connell, J R, Strachan, D P, Stefansson, K, van Duijri, C M, Abecasis, G R, Franke, L, Frayling, T M, McCarthy, M I, Visscher, P M, Scherag, A, Willer, C J, Boehnke, M, Mohlke, K L, Lindgren, C M, Beckmann, J S, Barroso, I, North, K E, Ingelsson, E, Hirschhorn, J N, Loos, R J F & Speliotes, E K 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-206 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197. Nature Publishing Group
Nature
Nature, 518(7538), 197-U401
Nature, Vol. 518, No 7538 (2015) pp. 197-206
Nature, vol. 518, no. 7538, pp. 197-206
Nature
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Locke, A E, Kahali, B, Berndt, S I, Justice, A E, Pers, T H, Day, F R, Powell, C, Vedantam, S, Buchkovich, M L, Yang, J, Croteau-Chonka, D C, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, J C, Winkler, T W, Wood, A R, Workalemahu, T, Faul, J D, Smith, J A, Zhao, J H, Zhao, W, Chen, J, Fehrmann, R, Hedman, A K, Karjalainen, J, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M & Bolton, J L & Bragg-Gresham, L & Buyske, S & Demirkan, A & Deng, G & Fraser, R M & Hayward, C & McLachlan, S & Campbell, H & Morris, A D & Price, J F & Rudan, I & Walker, M & Wilson, J F & Visscher, P M 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-U401 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197-U401. Nature Publishing Group
Nature, 518, 7538, pp. 197-206
Nature, 518, 197-206
Item does not contain fulltext Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9c5084ccf8e95018f370ac56cecd0a
https://research.vu.nl/en/publications/58992b26-1689-48dd-bb82-82548598fe61
https://research.vu.nl/en/publications/58992b26-1689-48dd-bb82-82548598fe61
Autor:
Benjamin Voight, Guillaume Pare, Ruth Loos, Michael Preuss, Åsa Johansson, Eco De Geus, Michael Weedon, Marjo-Riitta Jarvelin, Joyce Van Meurs, Torben Jørgensen, Kirsi Pietiläinen, Nicole Glazer, Mattias Lorentzon, Braxton Mitchell, Nicole Soranzo, Patricia Munroe, Ozren Polasek, Elisabeth Thiering, Marika Kaakinen, Carla Vogel, Jennie Hui, Elina Hypponen, ROBERTO ELOSUA, Amanda Bennett, Michael Stumvoll, Andrew Hattersley, Peter P Pramstaller, Lambertus Kiemeney, Sophie Visvikis-Siest, Vilmundur Gudnason, John Whittaker, Aroon Hingorani, Thor Aspelund, Dale Nyholt, Mary Feitosa, Vimal Karani, Mika Kähönen, Lachlan Coin, Malcolm Dunlop, Josee Dupuis, Terho Lehtimäki, Peter Visscher, Katja Aben, Daniel Witte, Cyrus Cooper, Stefan Pilz, Willem Ouwehand, Eleanor Wheeler, Peter Kovacs, Debbie A Lawlor, Kevin Jacobs, Evropi Theodoratou, Hana Lango Allen, Rosanda Mulic, Rui Li, Stephen Kritchevsky, Philippe Froguel, Soumya Raychaudhuri, Cornelia Van Duijn, Andrew Wood, Chiara Lanzani, Tonu Esko, Sadaf Farooqi, Reedik Mägi, Gerard Waeber, Claes Ohlsson, André Scherag, Marcus Kleber, Thomas Meitinger, Lina Zgaga, Denise Houston, Karl Michaëlsson, Robert Weyant, Thomas Wang, Paul Elliott, Robert Luben, Albert Vernon Smith, MANUELA UDA, Gonneke Willemsen, Mark McCarthy, Cecilia Lindgren, Olle Melander, Igor Rudan, Maris Teder-Laving, Liesbeth Vandenput
Publikováno v:
Plos Medicine, 10, e1001383
PLoS Medicine
Vimaleswaran, K S, Berry, D J, Lu, C, Tikkanen, E, Pilz, S, Hiraki, L T, Cooper, J D, Dastani, Z, Li, R, Houston, D K, Wood, A R, Michaëlsson, K, Vandenput, L, Zgaga, L, Yerges-Armstrong, L M, McCarthy, M I, Dupuis, J, Kaakinen, M, Kleber, M E, Jameson, K, Arden, N, Raitakari, O, Viikari, J, Lohman, K K, Ferrucci, L, Melhus, H, Ingelsson, E, Byberg, L, Lind, L, Lorentzon, M, Salomaa, V, Campbell, H, Dunlop, M, Mitchell, B D, Herzig, K H, Pouta, A, Hartikainen, A L, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Visscher, P M, van Duijn, C M, Streeten, E A, Theodoratou, E, Jula, A, Wareham, N J, Ohlsson, C, Frayling, T M, Kritchevsky, S B, Spector, T D, Richards, J B, Lehtimäki, T, Ouwehand, W H, Kraft, P, Cooper, C, März, W, Power, C, Loos, R J, Wang, T J, Järvelin, M R, Whittaker, J C, Hingorani, A D & Hyppönen, E 2013, ' Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts ', PLoS Medicine, vol. 10, no. 2, e1001383 . https://doi.org/10.1371/journal.pmed.1001383
Scopus-Elsevier
PLoS Medicine, 10(2):e1001383. Nature Publishing Group
PLoS Medicine, Vol 10, Iss 2, p e1001383 (2013)
Plos Medicine, 10, 2, pp. e1001383
PLoS Medicine, 10(2):e1001383. Public Library of Science
PLoS Med. 10:e1001383 (2013)
PLOS Medicine, vol. 10, no. 2, pp. e1001383
Vimaleswaran, K S, Berry, D J, Lu, C, Tikkanen, E, Pilz, S, Hiraki, L T, Cooper, J D, Dastani, Z, Li, R, Houston, D K, Wood, A R, Michaëlsson, K, Vandenput, L, Zgaga, L, Yerges-Armstrong, L M, McCarthy, M I, Dupuis, J, Kaakinen, M, Kleber, M E, Jameson, K, Arden, N, Raitakari, O, Viikari, J, Lohman, K K, Ferrucci, L, Melhus, H, Ingelsson, E, Byberg, L, Lind, L, Lorentzon, M, Salomaa, V, Campbell, H, Dunlop, M, Mitchell, B D, Herzig, K-H, Pouta, A, Hartikainen, A-L, Streeten, E A, Theodoratou, E, Jula, A, Wareham, N J, Ohlsson, C, Frayling, T M, Kritchevsky, S B, Spector, T D, Richards, J B, Lehtimäki, T, Ouwehand, W H & Kraft, P & Cooper, C 2013, ' Causal Relationship between Obesity and Vitamin D Status : Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts ', PLoS Medicine, vol. 10, no. 2, e1001383, pp. e1001383 . https://doi.org/10.1371/journal.pmed.1001383
PLoS Medicine
Vimaleswaran, K S, Berry, D J, Lu, C, Tikkanen, E, Pilz, S, Hiraki, L T, Cooper, J D, Dastani, Z, Li, R, Houston, D K, Wood, A R, Michaëlsson, K, Vandenput, L, Zgaga, L, Yerges-Armstrong, L M, McCarthy, M I, Dupuis, J, Kaakinen, M, Kleber, M E, Jameson, K, Arden, N, Raitakari, O, Viikari, J, Lohman, K K, Ferrucci, L, Melhus, H, Ingelsson, E, Byberg, L, Lind, L, Lorentzon, M, Salomaa, V, Campbell, H, Dunlop, M, Mitchell, B D, Herzig, K H, Pouta, A, Hartikainen, A L, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Visscher, P M, van Duijn, C M, Streeten, E A, Theodoratou, E, Jula, A, Wareham, N J, Ohlsson, C, Frayling, T M, Kritchevsky, S B, Spector, T D, Richards, J B, Lehtimäki, T, Ouwehand, W H, Kraft, P, Cooper, C, März, W, Power, C, Loos, R J, Wang, T J, Järvelin, M R, Whittaker, J C, Hingorani, A D & Hyppönen, E 2013, ' Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts ', PLoS Medicine, vol. 10, no. 2, e1001383 . https://doi.org/10.1371/journal.pmed.1001383
Scopus-Elsevier
PLoS Medicine, 10(2):e1001383. Nature Publishing Group
PLoS Medicine, Vol 10, Iss 2, p e1001383 (2013)
Plos Medicine, 10, 2, pp. e1001383
PLoS Medicine, 10(2):e1001383. Public Library of Science
PLoS Med. 10:e1001383 (2013)
PLOS Medicine, vol. 10, no. 2, pp. e1001383
Vimaleswaran, K S, Berry, D J, Lu, C, Tikkanen, E, Pilz, S, Hiraki, L T, Cooper, J D, Dastani, Z, Li, R, Houston, D K, Wood, A R, Michaëlsson, K, Vandenput, L, Zgaga, L, Yerges-Armstrong, L M, McCarthy, M I, Dupuis, J, Kaakinen, M, Kleber, M E, Jameson, K, Arden, N, Raitakari, O, Viikari, J, Lohman, K K, Ferrucci, L, Melhus, H, Ingelsson, E, Byberg, L, Lind, L, Lorentzon, M, Salomaa, V, Campbell, H, Dunlop, M, Mitchell, B D, Herzig, K-H, Pouta, A, Hartikainen, A-L, Streeten, E A, Theodoratou, E, Jula, A, Wareham, N J, Ohlsson, C, Frayling, T M, Kritchevsky, S B, Spector, T D, Richards, J B, Lehtimäki, T, Ouwehand, W H & Kraft, P & Cooper, C 2013, ' Causal Relationship between Obesity and Vitamin D Status : Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts ', PLoS Medicine, vol. 10, no. 2, e1001383, pp. e1001383 . https://doi.org/10.1371/journal.pmed.1001383
A mendelian randomization study based on data from multiple cohorts conducted by Karani Santhanakrishnan Vimaleswaran and colleagues re-examines the causal nature of the relationship between vitamin D levels and obesity.
Background Obesity is as
Background Obesity is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114ff45c9f3c5ccc860e181b421b1f0e
Autor:
Fredrik Karpe, Ivonne Jarick, Julius S. Ngwa, Alan F. Wright, Robert Luben, Aaron R. Folsom, Sailaja Vedantam, Veikko Salomaa, Markku J. Savolainen, Robert Clarke, Shah Ebrahim, Thomas A. Buchanan, Mao Fu, Albert Hofman, Philippe Goyette, Camilla H. Sandholt, Fabio Macciardi, Elizabeth K. Speliotes, Barbara McKnight, Anne McCarthy, Mika Kaehoenen, Christian Gieger, Jorma S. A. Viikari, Nicholas J. Timpson, Kirsti Kvaløy, Douglas F. Levinson, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Andrew A. Hicks, Niina Pellikka, Charles C. White, Leena Peltonen, Reedik Maegi, John-Olov Jansson, Qunyuan Zhang, Claudia Lamina, Robert C. Kaplan, Peter M. Visscher, Laura J. Scott, Claes Ohlsson, Brian Thomson, Jubao Duan, Heikki V. Huikuri, Stephen O'Rahilly, Anette P. Gjesing, David P. Strachan, Caroline S. Fox, Sekar Kathiresan, Anna-Liisa Hartikainen, Johannes Kettunen, Maris Teder-Laving, Erik Ingelsson, Mario A. Morken, Peter Kovacs, Elisabeth Widen, Caroline Hayward, Eleanor Wheeler, Jing Hua Zhao, Vilmundur Gudnason, Panos Deloukas, Jacqueline C. M. Witteman, Gert-Jan B. van Ommen, Eric Boerwinkle, Martin Wabitsch, Christian Hengstenberg, Beverley Balkau, Thor Aspelund, Neelam Hassanali, Paul M. Ridker, Nicole L. Glazer, Joyce B. J. van Meurs, Michel Marre, Alan James, Ben A. Oostra, David Meyre, Ida Surakka, Stefan Schreiber, Nigel W. Rayner, Heribert Schunkert, Thomas Quertermous, Stefan Gustafsson, Peter Kraft, Benjamin F. Voight, Irene Pichler, Olle Melander, Ozren Polasek, Antti Jula, Alan R. Sanders, Andrew R. Wood, Yoav Ben-Shlomo, Thomas Illig, Jianjun Liu, Gerard Waeber, André G. Uitterlinden, Torben Hansen, Helene Alavere, André Scherag, Paolo Manunta, Johannes Hebebrand, Themistocles L. Assimes, Stefan R. Bornstein, Jaakko Tuomilehto, Morris Brown, Jianfeng Xu, Yii-Der Ida Chen, Nancy L. Heard-Costa, Cristen J. Willer, Henrik Greonberg, Guillaume Lettre, John R. Thompson, Inês Barroso, John R. B. Perry, Andreas Ziegler, James F. Wilson, Christopher J. O'Donnell, Maurizio F. Facheris, Robert Lawrence, Jan Smit, Lyle J. Palmer, Ulf Gyllensten, Richard B. Hayes, Shengxu Li, Barbara Ludwig, Larry D. Atwood, Valgerdur Steinthorsdottir, Sabine Schipf, Jouko Saramies, Tanja Boes, Martin Ridderstråle, Jennie Hui, Lina Zgaga, Susann Scherag, Alexandra I. F. Blakemore, Marjolein Peters, Timo T. Valle, Nelson B. Freimer, Kay-Tee Khaw, Amy J. Swift, Michael Stumvoll, Miriam F. Moffatt, Cecilia M. Lindgren, Ayellet V. Segrè, Neil Robertson, Richard N. Bergman, Francis S. Collins, Ryan P. Welch, Mari-Liis Tammesoo, Devin Absher, Tamara B. Harris, Kari E. North, Manuela Uda, Karen L. Mohlke, Inga Prokopenko, Per Hall, Gudmar Thorleifsson, Marjo-Riitta Järvelin, Guillaume Paré, Stefan Gaget, G. Bragi Walters, Michael N. Weedon, Jean-Claude Tardif, Mary F. Feitosa, Anke Toenjes, Ken K. Ong, Cécile Lecoeur, Paavo Zitting, David S. Siscovick, Chih-Mei Chen, Peter Almgren, Anneli Pouta, Philippe Froguel, Pekka Jousilahti, Jaakko Kaprio, Maria Teresa Sciarrone Alibrandi, Sophie van Wingerden, Steven A. McCarroll, Oluf Pedersen, Shaun Purcell, Veronique Vitart, Leena Kinnunen, Markus Perola, Jacques S. Beckmann, Vincent Vatin, Christopher J. Groves, Zoltán Kutalik, Lu Qi, Volker Hoesel, Seppo Koskinen, Suzanne Rafelt, Anke Hinney, Annette Peters, David Schlessinger, Eero Kajantie, Jian Yang, Nicholas G. Martin, Joshua W. Knowles, Kristian Midthjell, Olivier Lantieri, Dorret I. Boomsma, Harry Campbell, Ulrich John, Kirsi H. Pietilaeinen, George Davey Smith, Carl G. P. Platou, Sarah H. Wild, Patricia B. Munroe, Iris M. Heid, Diana Marek, Michael Boehnke, Andres Metspalu, Hana Lango Allen, Peter Rzehak, Christine Cavalcanti-Proença, M. Carola Zillikens, Åsa Johansson, Anuj Goel, Andrew T. Hattersley, Massimo Mangino, Michael E. Goddard, Tim D. Spector, Winfried Rief, Jonathan Tyrer, Lachlan J. M. Coin, Peter P. Pramstaller, Narisu Narisu, John Beilby, Jonathan Stephens, Christina Barlassina, Pamela Fischer-Posovszky, Brenda W.J.H. Penninx, Kaisa Silander, Richard H. Myers, Jouke-Jan Hottenga, Eric E. Schadt, Francesco P. Cappuccio, Martin den Heijer, Fernando Rivadeneira, Lindsay L. Waite, Wilmar Igl, Igor Rudan, Manjinder S. Sandhu, Debbie A Lawlor, Kristian Hveem, Susanna Wiegand, Mari Nelis, Thomas Reinehr, Elisabeth Thiering, Inke R. Koenig, Stephan B. Felix, Fredrik Wiklund, Ian N. M. Day, Willem H. Ouwehand, Peter Schwarz, Richard M. Watanabe, Keri L. Monda, Kari Stefansson, Gudny Eiriksdottir, H-Erich Wichmann, Jianxin Shi, Najaf Amin, Carlos Iribarren, Heiko Krude, Dale R. Nyholt, Lenore J. Launer, Stephen J. Chanock, Harald Grallert, Hugh Watkins, Juergen Graessler, Tsegaselassie Workalemahu, Jeanette Erdmann, Mattias Lorentzon, Leif Groop, Teresa Ferreira, Chiara Lanzani, Johanna Kuusisto, Johan G. Eriksson, Tõnu Esko, Torben Jørgensen, Robert J. Weyant, Michael Preuss, Lambertus A. Kiemeney, Daniel I. Chasman, Daniel R. Witte, Kevin B. Jacobs, Nicole Soranzo, John M. C. Connell, Soumya Raychaudhuri, Jian'an Luan, Joshua C. Randall, Joachim Heinrich, Anthony J. Balmforth, Eva Fisher, Elizabeth S. Jewell, Alice M. Arnold, Nele Friedrich, Olli T. Raitakari, Henri Wallaschofski, Jeffrey R. O'Connell, Terho Lehtimaeki, Marika Kaakinen, Heather M. Stringham, Bo Isomaa, I. Sadaf Farooqi, Anna L. Dixon, Anne U. Jackson, Mark I. McCarthy, Lori L. Bonnycastle, Aila Rissanen, Joel N. Hirschhorn, Nilesh J. Samani, Aimo Ruokonen, Frank B. Hu, L. Adrienne Cupples, Amanda J. Bennett, Shamika Ketkar, Ruth J. F. Loos, Nicholas J. Wareham, Tiinamaija Tuomi, Timothy M. Frayling, Ulla Sovio, Georg Homuth, Liming Liang, Heiner Boeing, Unnur Thorsteinsdottir, Ingrid B. Borecki, Danielle M. Greenawalt, Rosanda Mulić, Ivana Kolcic, Talin Haritunians, Mark J. Caulfield, Marja-Liisa Lokki, Tanya M. Teslovich, Paul Elliott, Matt Neville, Nilanjan Chatterjee, Albert V. Smith, Andrew P. Morris, Fabio Busonero, Gonçalo R. Abecasis, Jaana Laitinen, Michael R. Erdos, Candace Guiducci, Lee M. Kaplan, Aki S. Havulinna, Pablo V. Gejman, Alan R. Shuldiner, Serena Sanna, David J. Hunter, Sonja I. Berndt, Carla I. G. Vogel, Alistair S. Hall, Karol Estrada, Sven Bergmann, Thomas Meitinger, Gonneke Willemsen, Andrew C. Heath, Katja K.H. Aben, Markku Laakso, Juha Sinisalo, Tuomas O. Kilpelaenen, Mark E. Cooper, Heike Biebermann, Eco J. C. de Geus, Grant W. Montgomery, Sophie Visvikis-Siest, Thomas W. Winkler, Ju-Hyun Park, Alex N. Parker, Peter S. Chines, James Nemesh, Nabila Bouatia-Naji, Wendy L. McArdle, Roberto Elosua, Markku S. Nieminen
Publikováno v:
Nature Genetics, 42(11), 937
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Hottenga, J J, de Geus, E J C, Martin, N G, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Zillikens, M C, Visscher, P M, Peltonen, L, van Duijn, C M, Thorsteinsdottir, U, Abecasis, G R, Barroso, I, Boehnke, M, Stefansson, K, North, K E, McCarthy, M I, Hirschhorn, J N, Ingelsson, E & Loos, R J F 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-948 . https://doi.org/10.1038/ng.686
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Aben, K K, Absher, D M, Amin, N, Dixon, A L, Fisher, E, Glazer, N L, Goddard, M E, Witte, D, Pedersen, O & MAGIC 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature genetics
Nature Genetics, 42(11), 937-948. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics, 42(11), 937-U53. Nature Publishing Group
Nature Genetics
Nature Genetics, 42, 937-48
Nature genetics, vol. 42, no. 11, pp. 937-948
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Allen, H L, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Campbell, H, Hayward, C, Vitart, V, Wild, S H, Zgaga, L, Rudan, I, Wilson, J F & Wright, A F & Visscher, P M 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature Genetics, 42, 11, pp. 937-48
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Hottenga, J J, de Geus, E J C, Martin, N G, Willemsen, G, Boomsma, D I, Penninx, B W J H, Uitterlinden, A G, Zillikens, M C, Visscher, P M, Peltonen, L, van Duijn, C M, Thorsteinsdottir, U, Abecasis, G R, Barroso, I, Boehnke, M, Stefansson, K, North, K E, McCarthy, M I, Hirschhorn, J N, Ingelsson, E & Loos, R J F 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-948 . https://doi.org/10.1038/ng.686
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Lango Allen, H, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Aben, K K, Absher, D M, Amin, N, Dixon, A L, Fisher, E, Glazer, N L, Goddard, M E, Witte, D, Pedersen, O & MAGIC 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature genetics
Nature Genetics, 42(11), 937-948. Nature Publishing Group
Nature Genetics; Vol 42
Nature Genetics, 42(11), 937-U53. Nature Publishing Group
Nature Genetics
Nature Genetics, 42, 937-48
Nature genetics, vol. 42, no. 11, pp. 937-948
Speliotes, E K, Willer, C J, Berndt, S I, Monda, K L, Thorleifsson, G, Jackson, A U, Allen, H L, Lindgren, C M, Luan, J, Mägi, R, Randall, J C, Vedantam, S, Winkler, T W, Qi, L, Workalemahu, T, Heid, I M, Steinthorsdottir, V, Stringham, H M, Weedon, M N, Wheeler, E, Wood, A R, Ferreira, T, Weyant, R J, Segrè, A V, Estrada, K, Liang, L, Nemesh, J, Park, J-H, Gustafsson, S, Kilpeläinen, T O, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, M F, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, A V, Welch, R, Zhao, J H, Campbell, H, Hayward, C, Vitart, V, Wild, S H, Zgaga, L, Rudan, I, Wilson, J F & Wright, A F & Visscher, P M 2010, ' Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ', Nature Genetics, vol. 42, no. 11, pp. 937-48 . https://doi.org/10.1038/ng.686
Nature Genetics, 42, 11, pp. 937-48
Obesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined aSociations betwEn body maS index and ĝ̂1/42.8 miLion SNPs in up to 123,8
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7dd940bce9e9209645e6816dc4e081
http://hdl.handle.net/1887/116783
http://hdl.handle.net/1887/116783