Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Gary J. Nabel"'
Autor:
Yanfeng Zhou, Yu Qiu, Nicole Darricarrère, Masaru Kanekiyo, Adrian Creanga, Rebecca A. Gillespie, Syed M. Moin, Jacqueline Saleh, Jose Sancho, Te-Hui Chou, Ruijun Zhang, Shujia Dai, Anthony Moody, Kevin O. Saunders, Michelle C. Crank, John R. Mascola, Barney S. Graham, Chih-Jen Wei, Gary J. Nabel
Publikováno v:
Microscopy and Microanalysis. 27:2848-2850
Autor:
Chih-Jen Wei, John R. Mascola, Barney S. Graham, Michelle C. Crank, John Shiver, Gary J. Nabel
Publikováno v:
Nature Reviews. Drug Discovery
Seasonal influenza vaccines lack efficacy against drifted or pandemic influenza strains. Developing improved vaccines that elicit broader immunity remains a public health priority. Immune responses to current vaccines focus on the haemagglutinin head
Autor:
Dana M. Lord, Katarina Radosevic, Christian Beil, Gregory Ulinski, Thomas Bertrand, Cendrine Lemoine, Zhi Yong Yang, Srinivas S. Rao, Ronnie Wei, Gejing Deng, Béatrice Cameron, Valeriya Posternak, Bailin Zhang, Paul Ferrari, Lan Wu, Zhili Song, Tarik Dabdoubi, Aiqun Li, Virna Cortez-Retamozo, Stéphanie Pouzieux, Marielle Chiron, Gary J. Nabel, Jennifer Fretland, Fangxian Sun, Anna Park, Nizar El-Murr, Rita Vicente, Elisa Francesconi, Ercole Rao, Peter A. Piepenhagen, Catherine Prades, Huawei Qiu, Edward Seung, Beatriz Ospina, Patrick Kirby, Ling Xu
Publikováno v:
Nature Cancer. 1:86-98
Despite the significant therapeutic advances provided by immune-checkpoint blockade and chimeric antigen receptor T cell treatments, many malignancies remain unresponsive to immunotherapy. Bispecific antibodies targeting tumor antigens and activating
Autor:
Jean Haensler, John R. Mascola, Thorsten U. Vogel, Ram Dharanipragada, Michael R. Reardon, Pradeep K. Dhal, Rebecca S. Rudicell, Barney S. Graham, Te-Hui Chou, Daniel Simard, Heather D. Kamp, Kanwen Yang, Joshua M. DiNapoli, Luis Z. Avila, Masaru Kanekiyo, Harry Kleanthous, Marie Garinot, Kurt Swanson, Lingyi Zheng, Xiaochu Duan, Chih-Jen Wei, Shujia Dai, Olivier Bedel, Rebecca A. Gillespie, Magnus Besev, Gary J. Nabel
Publikováno v:
Vaccine
Seasonal influenza vaccines represent a positive intervention to limit the spread of the virus and protect public health. Yet continual influenza evolution and its ability to evade immunity pose a constant threat. For these reasons, vaccines with imp
Autor:
Jason Hataye, Zhi Yong Yang, Nicole A. Doria-Rose, John R. Mascola, Giulia Fabozzi, Hui Li, Tongqing Zhou, Wei Shi, Kylie March, Brandon F. Keele, George M. Shaw, Joseph P. Casazza, Kathryn E. Foulds, Joana Dias, Wanwisa Promsote, Gary J. Nabel, Michelle D. Cully, Richard A. Koup, Xuejun Chen, Amarendra Pegu, Ling Xu, Ronnie Wei, Hui Geng, Cuiping Liu, Amy Noe, Jeffrey D. Lifson, Cassandra G. Almasri, Ercole Rao, Constantinos Petrovas, Mangaiarkarasi Asokan, John-Paul Todd, Krisha McKee, Christine M. Fennessey, Stephen D. Schmidt, Eun Sung Yang, Megan E. DeMouth, Keyun Wang, Shing-Fen Kao
Publikováno v:
SSRN Electronic Journal.
Broadly neutralizing antibodies (bNAbs) represent an alternative to drug therapy for the treatment of HIV-1 infection. Immunotherapy with single bNAbs often leads to emergence of escape variants, suggesting a potential benefit of combination bNAb the
Autor:
Masaru Kanekiyo, Jose Sancho, Ruijun Zhang, John R. Mascola, Kevin O. Saunders, Gary J. Nabel, Anthony Moody, Barney S. Graham, Chih Jen Wei, Shujia Dai, Yanfeng Zhou, Jacqueline Saleh, Syed M. Moin, Adrian Creanga, Nicole Darricarrère, Michelle C. Crank, Te Hui Chou, Rebecca A. Gillespie, Yu Qiu
Publikováno v:
Science translational medicine. 13(583)
Seasonal influenza vaccines confer protection against specific viral strains but have restricted breadth that limits their protective efficacy. The H1 and H3 subtypes of influenza A virus cause most of the seasonal epidemics observed in humans and ar
Autor:
Kurt Swanson, Bijaya Sharma, Ondrej Hajdusek, Chih-Jen Wei, Linden T. Hu, Heather D. Kamp, Pradeep K. Dhal, Radek Sima, Gary J. Nabel, Ronnie Wei, Aurelie Kern, Ram Dharanipragada
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-10 (2020)
NPJ Vaccines
NPJ Vaccines
A growing global health concern, Lyme disease has become the most common tick-borne disease in the United States and Europe. Caused by the bacterial spirochete Borrelia burgdorferi sensu lato (sl), this disease can be debilitating if not treated prom
Autor:
Sankalp Gupta, Zachary P. Williams, Darin K. Edwards, Linong Zhang, Scott Gallichan, Chih-Jen Wei, Haritha Adhikarla, Vincent Pavot, Jennifer N. Rainho-Tomko, Judith Alamares-Sapuay, Lilibeth Lanza, Gary J. Nabel, Michael Peredelchuk, Michael G. Kishko, Kurt Swanson, Sudha Chivukula, Heesik Yoon, Nicholas Jackson
Publikováno v:
Science immunology. 5(47)
A stabilized form of the respiratory syncytial virus (RSV) fusion (F) protein has been explored as a vaccine to prevent viral infection because it presents several potent neutralizing epitopes. Here, we used a structure-based rational design to optim
Autor:
Andreas Ebneth, Astrid Bottelbergs, Cindy Wintmolders, Philippe Goniot, Nathalie Schussler, Emmanuel Brault, Gary J. Nabel, David R. Riddell, Yaming Wang, Alexis Bretteville, Margaret M. Racke, Véronique Blanc, Bart Roucourt, Zhi Yong Yang, Laurent Pradier, Tyler McGathey, Bradford Elmer, Jirong Lu, Michael J. O'Neill, Martine Latta-Mahieu, Liesbeth Mertens, Caroline Hersley, Paul Ferrari, Mati Lopez-Grancha, Pascal Barneoud, Nicolas Moindrot, Philippe Bertrand, Véronique Blanchard, Valerie Roudieres, Ling Liu, Sofie Carmans, Peter Larsen
Publikováno v:
Glia. 66:492-504
Chronic inflammation represents a central component in the pathogenesis of Alzheimer's disease (AD). Recent work suggests that breaking immune tolerance by Programmed cell Death-1 (PD1) checkpoint inhibition produces an IFN-γ-dependent systemic immu
Autor:
Zachary Mankoff, Ronnie Wei, Dennis R. Burton, Krisha McKee, Dana M. Lord, Richard A. Koup, Christian Lange, Wulf Dirk Leuschner, Keyun Wang, Mario Roederer, Stephen D. Schmidt, Tongqing Zhou, Dan H. Barouch, Rebecca Sendak, Lawrence J. Tartaglia, Sijy O'Dell, Zhi Yong Yang, Misook Choe, Robert T. Bailer, Lan Wu, John R. Mascola, Mangaiarkarasi Asokan, Young Do Kwon, Amarendra Pegu, Ercole Rao, Ling Xu, Mark Connors, Peter D. Kwong, Jochen Kruip, Xuejun Chen, John-Paul Todd, Gejing Deng, Mark K. Louder, Gary J. Nabel, Nicole A. Doria-Rose, Christian Beil, Jochen Beninga
Publikováno v:
Science. 358:85-90
A triple threat for HIV The HIV virus continually evolves tricks to evade elimination by the host. Prevention and a cure will likely rely on broadly neutralizing antibodies that can recognize and conquer multiple viral strains or subtypes. Xu et al.