Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Emily L. Clark"'
Autor:
Adebabay Kebede, Ayelle Abeba, Suliman Latairish, Olivier Hanotte, Mukhtar Omar Agoub, Emily L. Clark, Hassan Hussein Musa, Joram M. Mwacharo, Abulgasim Ahbara, Pamela Wiener, Christelle Robert
African sheep manifest diverse but distinct physio-anatomical traits which are the outcomes of natural- and human-driven selection. Here, we generated 34.8 million variants from 150 indigenous African sheep genomes sequenced at an average depth of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0e494a81f88bde7b5b78f86fe9c739
https://doi.org/10.1101/2021.11.17.469022
https://doi.org/10.1101/2021.11.17.469022
Autor:
Francesc X Donadeu, Emily L. Clark, Cheryl Ashworth, Alan Archibald, Musa A. Hassan, Shernae A. Woolley, Yennifer Cortes Araya, Claire Stenhouse, Martin Johnsson, Mazdak Salavati, Michelle M. Halstead
There is very little species-specific information about how the genome is regulated in domestic pigs (Sus scrofa). This lack of knowledge hinders efforts to define and predict the effects of genetic variants in pig breeding programmes. In order to ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe791086612dbf2ad72d64668a2b4af
https://doi.org/10.1101/2021.01.21.426812
https://doi.org/10.1101/2021.01.21.426812
Autor:
James Prendergast, Christelle Robert, David A. Hume, Juliane Friedrich, Emily L. Clark, Pamela Wiener, David Wragg, Mazdak Salavati, Olivier Hanotte, Deepali Vasoya, Mick Watson, Joram M. Mwacharo, Abulgasim Ahbara, Ayele Abebe, Adebabay Kebede, Appolinaire Djikeng
Publikováno v:
Genome Biology and Evolution
Wiener, P, Robert, C, Ahbara, A, Salavati, M, Abebe, A, Kebede, A, Wragg, D, Friedrich, J, Vasoya, D, Hume, D A, Djikeng, A, Watson, M, Prendergast, J, Hanotte, O, Mwacharo, J M & Clark, E 2021, ' Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations ', Genome Biology and Evolution . https://doi.org/10.1093/gbe/evab014
Wiener, P, Robert, C, Ahbara, A, Salavati, M, Abebe, A, Kebede, A, Wragg, D, Friedrich, J, Vasoya, D, Hume, D A, Djikeng, A, Watson, M, Prendergast, J, Hanotte, O, Mwacharo, J M & Clark, E 2021, ' Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations ', Genome Biology and Evolution . https://doi.org/10.1093/gbe/evab014
Great progress has been made over recent years in the identification of selection signatures in the genomes of livestock species. This work has primarily been carried out in commercial breeds for which the dominant selection pressures are associated
Autor:
Lucas Lefevre, R. Scott Pirie, David A. Hume, Neil Hudson, Emily L. Clark, Tim Mair, Zofia M. Lisowski
Publikováno v:
Lisowski, Z, Lefevre, L, Mair, T S, Clark, E, Hudson, N, Hume, D A & Pirie, S 2021, ' Use of quantitative real-time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis externa of horses undergoing small intestinal resection ', Equine Veterinary Journal . https://doi.org/10.1111/evj.13429
Background: Studies in rodents and humans have demonstrated that intestinal manipulation or surgical trauma initiates an inflammatory response in the intestine which results in leukocyte recruitment to the muscularis externa causing smooth muscle dys
Autor:
Sigbjørn Lien, Daniel J. Macqueen, Christa Kühn, Alan Archibald, James M. Reecy, Ross D. Houston, Diego Robledo, Elisabetta Giuffra, Hans D. Daetwyler, Peter W. Harrison, Martien A. M. Groenen, Mick Watson, Emily L. Clark, Christopher K. Tuggle
Publikováno v:
Genome Biology
Genome Biology, 21(1)
Clark, E, Archibald, A, Daetwyler, H D, Groenen, M A, Harrison, P W, Houston, R, Kuhn, C, Lien, S, Macqueen, D, Reecy, J M, Robledo, D, Watson, M, Tuggle, C K & Guiffra, E 2020, ' From FAANG to Fork: Application of Highly Annotated Genomes to Improve Farmed Animal Production ', Genome Biology . https://doi.org/10.1186/s13059-020-02197-8
Genome Biology 21 (2020) 1
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02197-8⟩
Genome Biology, BioMed Central, 2020, 21 (1), ⟨10.1186/s13059-020-02197-8⟩
Genome Biology, 21(1)
Clark, E, Archibald, A, Daetwyler, H D, Groenen, M A, Harrison, P W, Houston, R, Kuhn, C, Lien, S, Macqueen, D, Reecy, J M, Robledo, D, Watson, M, Tuggle, C K & Guiffra, E 2020, ' From FAANG to Fork: Application of Highly Annotated Genomes to Improve Farmed Animal Production ', Genome Biology . https://doi.org/10.1186/s13059-020-02197-8
Genome Biology 21 (2020) 1
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02197-8⟩
Genome Biology, BioMed Central, 2020, 21 (1), ⟨10.1186/s13059-020-02197-8⟩
The Food and Agriculture Organisation of the United Nations (FAO) reports that by the year 2050 the global human population is likely to reach 9.7 billion, rising to 11.2 billion by 2100 (https://population.un.org/wpp/Publications/Files/Key_Findings_
Autor:
Mazdak Salavati, Alex Caulton, Richard Clark, Iveta Gazova, Timothy P. L. Smith, Kim C. Worley, Noelle E. Cockett, Alan L. Archibald, Shannon M. Clarke, Brenda M. Murdoch, Emily L. Clark
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Salavati, M, Caulton, A, Clark, R, Gazova, I, Smith, T P L, Worley, K C, Cockett, N E, Archibald, A, Clarke, S M, Murdoch, B & Clark, E 2020, ' Global analysis of transcription start sites in the new ovine reference genome (Oar rambouillet v1.0) ', Frontiers in genetics . https://doi.org/10.3389/fgene.2020.580580
Salavati, M, Caulton, A, Clark, R, Gazova, I, Smith, T P L, Worley, K C, Cockett, N E, Archibald, A, Clarke, S M, Murdoch, B & Clark, E 2020, ' Global analysis of transcription start sites in the new ovine reference genome (Oar rambouillet v1.0) ', Frontiers in genetics . https://doi.org/10.3389/fgene.2020.580580
The overall aim of the Ovine FAANG project is to provide a comprehensive annotation of the new highly contiguous sheep reference genome sequence (Oar rambouillet v1.0). Mapping of transcription start sites (TSS) is a key first step in understanding t
Autor:
Martien A. M. Groenen, Mick Watson, Ross D. Houston, Elisabetta Giuffra, Christa Kühn, Peter W. Harrison, Christopher K. Tuggle, Sigbjørn Lien, Hans D. Daetwyler, Emily L. Clark, Alan Archibald, Diego Robledo, James M. Reecy, Daniel J. Macqueen
Here we review and describe a set of research priorities to meet present and future challenges posed to farmed animal production that build on progress, successes and resources from the Functional Annotation of ANimal Genomes (FAANG) project.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c2dcfbefd58f292b16b30c4d6b0e967
https://doi.org/10.20944/preprints202010.0118.v1
https://doi.org/10.20944/preprints202010.0118.v1
Autor:
Vicky E MacRae, David A. Hume, Greg R. Markby, Kim M. Summers, Brendan Corcoran, Stephen J. Bush, Emily L. Clark, Hiu-Gwen Tsang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Tsang, G, Clark, E, Markby, G, Bush, S, Hume, D, Corcoran, B, MacRae, V & Summers, K 2020, ' Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries). ', Frontiers in genetics, vol. 11 . https://doi.org/10.3389/fgene.2020.00919
Frontiers in Genetics
Tsang, G, Clark, E, Markby, G, Bush, S, Hume, D, Corcoran, B, MacRae, V & Summers, K 2020, ' Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries). ', Frontiers in genetics, vol. 11 . https://doi.org/10.3389/fgene.2020.00919
Frontiers in Genetics
The maintenance of a healthy cardiovascular system requires expression of genes that contribute to essential biological activities and repression of those that are associated with functions likely to be detrimental to cardiovascular homeostasis. Vasc
Autor:
Stephen J. Bush, Mary E. B. McCulloch, Zofia M. Lisowski, Charity Muriuki, Emily L. Clark, Rachel Young, Clare Pridans, James G. D. Prendergast, Kim M. Summers, David A. Hume
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Bush, S, Mcculloch, M, Lisowski, Z, Muriuki, C, Clark, E, Young, R, Pridans, C, Prendergast, J, Summers, K & Hume, D 2020, ' Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophages. ', Frontiers in Cell and Developmental Biology . https://doi.org/10.3389/fcell.2020.00661
Frontiers in Cell and Developmental Biology
Bush, S, Mcculloch, M, Lisowski, Z, Muriuki, C, Clark, E, Young, R, Pridans, C, Prendergast, J, Summers, K & Hume, D 2020, ' Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophages. ', Frontiers in Cell and Developmental Biology . https://doi.org/10.3389/fcell.2020.00661
Frontiers in Cell and Developmental Biology
Mammalian macrophages differ in their basal gene expression profiles and response to the toll-like receptor 4 (TLR4) agonist, lipopolysaccharide (LPS). In human macrophages, LPS elicits a temporal cascade of transient gene expression including feed f
Autor:
Mazdak Salavati, Richard Clark, Emily L. Clark, Timothy P. L. Smith, Iveta Gazova, Shannon M. Clarke, Brenda M. Murdoch, Kim C. Worley, Noelle E. Cockett, Alan Archibald, Alex Caulton
The overall aim of the Ovine FAANG project is to provide a comprehensive annotation of the new highly contiguous sheep reference genome sequence (Oar rambouillet v1.0). Mapping of transcription start sites (TSS) is a key first step in understanding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8abdaa5d2ca85725212e5e9117f52302
https://doi.org/10.1101/2020.07.06.189480
https://doi.org/10.1101/2020.07.06.189480