Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emi Ota Machida"'
Autor:
Kornel E. Schuebel, Stephen B. Baylin, Yang Y. Yu, Steven A. Belinsky, Christine A. Stidley, Mathewos Tessema, Emi Ota Machida
Publikováno v:
Carcinogenesis. 30:1132-1138
Aberrant promoter hypermethylation is one of the major mechanisms in carcinogenesis and some critical growth regulatory genes have shown commonality in methylation across solid tumors. Twenty-six genes, 14 identified through methylation in colon and
Autor:
D. Neil Watkins, Leander Van Neste, Stephen B. Baylin, Hariharan Easwaran, Mingzhou Guo, Sabine C. Glöckner, James G. Herman, Wei Zhang, Kornel E. Schuebel, Nita Ahuja, David H. Wang, Emi Ota Machida
Publikováno v:
Cancer Research. 68:2764-2772
SRY-box containing gene 17 (Sox17) is a member of the high mobility group (HMG) transcription factor superfamily, which plays critical roles in the regulation of development and stem/precursor cell function, at least partly through repression of Wnt
Autor:
Genevieve Pridham, James G. Herman, Edward Gabrielson, Yu Han, Craig M. Hooker, Emi Ota-Machida, Stephen Ames, Steven Piantadosi, Stephen C. Yang, Malcolm V. Brock, Stephen B. Baylin, Steven A. Belinsky, Sabine C. Glöckner, Kristen Pelosky, Mingzhou Guo
Publikováno v:
The New England journal of medicine, vol 358, iss 11
Brock, MV; Hooker, CM; Ota-Machida, E; Han, Y; Guo, M; Ames, S; et al.(2008). DNA methylation markers and early recurrence in stage I lung cancer. New England Journal of Medicine, 358(11), 1118-1128. doi: 10.1056/NEJMoa0706550. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3nd5k29c
Brock, MV; Hooker, CM; Ota-Machida, E; Han, Y; Guo, M; Ames, S; et al.(2008). DNA methylation markers and early recurrence in stage I lung cancer. New England Journal of Medicine, 358(11), 1118-1128. doi: 10.1056/NEJMoa0706550. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3nd5k29c
Background: Despite optimal and early surgical treatment of non-small-cell lung cancer (NSCLC), many patients die of recurrent NSCLC. We investigated the association between gene methylation and recurrence of the tumor. Methods: Fifty-one patients wi
Autor:
Marco A. Riojas, Sabine C. Glöckner, Emi Ota Machida, Nita Ahuja, Stephen B. Baylin, Mingzhou Guo
Publikováno v:
Cancer Biology & Therapy. 6:1710-1716
The hypermethylation of tumor-suppressor gene promoter regions has been shown to result in the epigenetic inactivation of many genes. ASC/TMS1 is a pro-apoptotic gene that has been shown to be methylated in many different human neoplasms. The methyla
Autor:
Wei Zhang, Jun Amano, Malcolm V. Brock, Leander Van Neste, Julien D.F. Licchesi, Stephen B. Baylin, Noreli Franco, Alicia Hulbert, Craig M. Hooker, Emi Ota Machida, Kornel E. Schuebel, Mathewos Tessema, Steven A. Belinsky, Sabine C. Glöckner, John Wrangle, James G. Herman, Nita Ahuja, Ludmila Danilova, Hariharan Easwaran
Purpose: Non–small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the world. Novel diagnostic biomarkers may augment both existing NSCLC screening methods as well as molecular diagnostic tests of surgical specimens to more acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23167cad5d299ecf0b6fc3d85537882
https://europepmc.org/articles/PMC4019442/
https://europepmc.org/articles/PMC4019442/
Autor:
Randy Willink, Malcolm V. Brock, Steven A. Belinsky, Stephen B. Baylin, Mathewos Tessema, Wayne Yu, Leander Van Neste, Emi Ota Machida, Christine A. Stidley, Kieu Do, Yang Y. Yu
Publikováno v:
Cancer research. 68(6)
Chromosomal aberrations associated with lung cancer are frequently observed in the long arm of chromosome 6. A candidate susceptibility locus at 6q23-25 for lung cancer was recently identified; however, no tumor suppressor genes inactivated by mutati
Autor:
William H. Westra, James G. Herman, Emi Ota Machida, Stephen B. Baylin, Julien D.F. Licchesi, Craig M. Hooker
Publikováno v:
Carcinogenesis. 29(5)
Background: Atypical adenomatous hyperplasia (AAH) is now recognized as a precursor lesion from which lung adenocarcinomas arise and thus represents an ideal target for studying the early genetic and epigenetic alterations associated with lung tumori