Zobrazeno 1 - 10
of 281
pro vyhledávání: '"David A. Price"'
Autor:
Christopher B. Ball, Jeffrey Meier, David H. Price, Benjamin M Spector, Mrutyunjaya Parida, Donal S. Luse, Ming Li
Publikováno v:
Nature Communications. 13
Interactions of the RNA polymerase II (Pol II) preinitiation complex (PIC) and paused early elongation complexes with the first downstream (+1) nucleosome are thought to be functionally important. However, current methods are limited for investigatin
Publikováno v:
Nucleic Acids Research
To better understand human RNA polymerase II (Pol II) promoters in the context of promoter-proximal pausing and local chromatin organization, 5′ and 3′ ends of nascent capped transcripts and the locations of nearby nucleosomes were accurately ide
Autor:
Kerryn A. Moore, Julie A. Simpson, Rosalind E. Howes, David J. Price, Angela Devine, Benedikt Ley, Sabine Dittrich, Ric N. Price
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Tafenoquine has been licensed for the single-dose radical cure of Plasmodium vivax in adults; however, it is only recommended in patients with > 70% of normal glucose-6-phosphate dehydrogenase (G6PD) activity. Because this may hinder widespread use,
Autor:
Austin B. Moyle, Daisy W. Leung, Safder Ganaie, Michael R. Kujawa, Devin A. Boyles, Xiaoxia Cui, Takeshi Egawa, Aidan R. Cole, David A. Price, Wenjie Wang, Monica F. Sentmanat, Michael L. Gross, Ryan M. Hoehl, Herbert W. Virgin, Gaya K. Amarasinghe, Sachdev S. Sidhu, Amy L. Hartman, John G. Doench, Cynthia M. McMillen, Anita K. McElroy, Annie X. Feng, Matthew Demers, Sean P. J. Whelan, Joan Teyra, Tom J. Brett, Anthony Orvedahl, Shane Miersch, Nawneet Mishra, Joseph R. Albe, Madeline M. Schwarz, Nicole D. Wagner, Zachary T. Koenig, Lia Cardarelli, Sarah H. Stubbs
Publikováno v:
Cell
Rift Valley Fever Virus (RVFV) is a zoonotic pathogen with pandemic potential. RVFV entry is mediated by the viral glycoprotein (Gn), but host entry factors remain poorly defined. Our genome-wide CRISPR screen identified low-density lipoprotein recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4526e72964ff21055ddcb4d8d6c2fff1
https://europepmc.org/articles/PMC8786218/
https://europepmc.org/articles/PMC8786218/
Autor:
David H. Price, Nicolas Buisine, Patricia Uguen, Duy Nguyen, Olivier Fayol, Annemieke A. Michels, Olivier Bensaude
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA polymerase II elongation. Although its primary sequence varies in protostomes, its secondary structure and function are cons
Autor:
Mrutyunjaya Parida, Geoffrey Collins, David H. Price, Qiaolin Hu, Jeffery L. Meier, Ming Li, Christopher B. Ball
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009796 (2021)
PLoS Pathogens
PLoS Pathogens
Beta- and gammaherpesviruses late transcription factors (LTFs) target viral promoters containing a TATT sequence to drive transcription after viral DNA replication has begun. Human cytomegalovirus (HCMV), a betaherpesvirus, uses the UL87 LTF to bind
Autor:
Andrew K. Sewell, Anzelika Rubina, Sian Llewellyn-Lacey, John S. Bridgeman, Hugo A. van den Berg, Kelly L. Miners, Ore Francis, Linda Wooldridge, James E. McLaren, Lea Knezevic, Mathew Clement, David K. Cole, Kristin Ladell, David A. Price, Tamsin Dockree
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Sufficient immune coverage of the peptide universe within a finite host requires highly degenerate T cell receptors (TCRs). However, this inherent need for antigen cross-recognition is associated with a high risk of autoimmunity, which c
Autor:
Kamala Thriemer, Ratni Indrawanti, Enny Kenangalem, Ric N. Price, Jeanne Rini Poespoprodjo, David J. Price, Niamh Meagher, Freis Candrawati, Faustina Helena Burdam, Benedikt Ley, Leily Trianty, Julie A. Simpson
Publikováno v:
The Lancet. Infectious diseases. 22(3)
Background There is a high risk of Plasmodium vivax recurrence in patients treated for Plasmodium falciparum malaria in co-endemic areas. Primaquine radical cure has the potential to reduce P vivax recurrences in patients presenting with P falciparum
Publikováno v:
Methods. :165-176
Transcription by RNA polymerase II (Pol II) is controlled during initiation, elongation, and termination by a large variety of transcription factors, the state of chromatin modifications, and environmental conditions. Herein we describe experimental
Autor:
Megan Templin, David E. Price, Janet P. Niemeier, Ashley S Long, Andrew McWilliams, Paul B. Perrin, Charity G Patterson
Publikováno v:
Athletic Training & Sports Health Care. 11:28-36