Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Chang Ohk Sung"'
Autor:
Eun Jung Lee, Bora Oh, Chang Ohk Sung, Deokhoon Kim, Gi-Won Song, Jihyun Song, Naomi Park, Yoo-Jin Oh, Jihyun An, Won-Kyung Kim, Ji-Hye Oh, Han Chu Lee, Ju Hyun Shim, Eric Letouzé, Hyo Jeong Kang, Eunsil Yu, Jessica Zucman-Rossi, Ha Ii Kim, Dae Ghon Kim
Publikováno v:
Hepatology. 75:997-1011
Despite the epidemiological association between intrahepatic cholangiocarcinoma (iCCA) and HBV infection, little is known about the relevant oncogenic effects. We sought to identify the landscape and mechanism of HBV integration, along with the genom
Autor:
Chang Ohk Sung, Sun Mi Lee
Publikováno v:
Pancreatology. 21:920-927
Objective Adenosquamous carcinoma of the pancreas (ASCP) is a rare histologic subtype of pancreatic carcinoma. The clinicopathologic characteristics and surgical outcomes of ASCP are poorly understood due to the rarity of this disease. Recently, prom
Autor:
Charles Lee, Deukchae Na, Chang Ohk Sung, Sung Yup Cho, Dongjun Jang, Sangeun Lee, Hae Rim Jung, Won-Suk Lee, Joon Yong An, Eui Man Jeong, Seoyeon Min, Seungjae Shin, Jinjoo Kang, Yumi Oh, Ji Won Kim
Publikováno v:
Oncogene. 40:3287-3302
Metastatic or recurrent colorectal cancer (CRC) patients require systemic chemotherapy, but the therapeutic options of targeted agents remain limited. CRC patients with KRAS or BRAF gene mutations exhibit a worse prognosis and are resistant to anti-E
Autor:
Dakeun Lee, Jin-Hyung Heo, Chang Ohk Sung, Ji Mi Ahn, Seokhwi Kim, Won Jung Bae, Kyoung-Mee Kim, Kyeong Woon Choi
Publikováno v:
Modern Pathology. 34:672-683
Although a certain proportion of intramucosal carcinomas (IMCs) of the stomach does metastasize, the majority of patients are currently treated with endoscopic resection without lymph node dissection, and this potentially veils any existing metastasi
Autor:
Sun Young Kim, Chang Ohk Sung, Tae Won Kim, Hyun Jung Lee, Jaeyong Choi, Jeong Eun Kim, Jong Il Kim, Yong Sang Hong
Publikováno v:
Experimental & Molecular Medicine
The global incidence of early-onset colorectal cancer (EO-CRC) is rapidly rising. However, the reason for this rise in incidence as well as the genomic characteristics of EO-CRC remain largely unknown. We performed whole-exome sequencing in 47 cases
Autor:
Sung-Min Chun, Jinyeong Lim, Eun Na Kim, Chang Ohk Sung, Won-Kyung Kim, Ji-Hye Oh, Hyeonjin Lee, Ji-Young Lee, Jihun Kim, Eun Jeong Cho
Publikováno v:
Journal of Human Genetics. 66:777-784
Mosaicisms caused by postzygotic mutational events are of increasing interest because of their potential association with various human diseases. Postzygotic somatic mutations have not been well characterized however in terms of their developmental l
Autor:
Chang Ohk Sung, Ji-Hye Oh
Publikováno v:
Journal of Medical Genetics. 58:433-441
BackgroundSomatic mutations are a major driver of cancer development and many have now been identified in various cancer types, but the comprehensive somatic mutation status of the normal tissues matched to tumours has not been revealed.MethodWe anal
Autor:
Chang Ohk Sung, Insuk Sohn, Jihun Kim, Eun Jeong Cho, Sung-Min Chun, Se Jin Jang, Ji-Young Lee, Ji-Hye Oh
Publikováno v:
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-11 (2020)
Tumor mutation burden (TMB) is an emerging biomarker, whose calculation requires targeted sequencing of many genes. We investigated if the measurement of mutation counts within a single gene is representative of TMB. Whole-exome sequencing (WES) data
Autor:
Young Jae Lee, Chang Ohk Sung, Ha Young Lee, Min-Je Kim, Yong-Man Kim, Sung Wan Kang, Shin-Wha Lee
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9638, p 9638 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9638, p 9638 (2021)
Immunoprofiling has an established impact on the prognosis of several cancers
however, its role and definition in high-grade serous ovarian cancer (HGSOC) are mostly unknown. This study is to investigate immunoprofiling which could be a prognost
however, its role and definition in high-grade serous ovarian cancer (HGSOC) are mostly unknown. This study is to investigate immunoprofiling which could be a prognost
Autor:
Ji-Hye Oh, Hee Chul Chung, Seok-Hyung Kim, Hyeonjin Lee, Chang Ohk Sung, Dakeun Lee, Won-Kyung Kim, Eun Jeong Cho
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine