Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Basil Sharrack"'
Autor:
Kathleen Quigley, Richard K. Burt, Basil Sharrack, John A. Snowden, Paul Tappenden, Roumen Balabanov, Xiaoqiang Han
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology, Vol 12 (2021)
Background: Intravenous immunoglobulin (IVIG) is effective as standard first line therapy for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), but some patients remain dependent on its long-term use. Recently, we have reported that a
Autor:
Milena De Felice, Basil Sharrack, Tennore Ramesh, David Burrows, Alexander McGown, Arshad Majid, Saurabh A. Jain
Publikováno v:
Multiple Sclerosis Journal. 25:306-324
Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disease of the central nervous system. Animal models of MS have been critical for elucidating MS pathological mechanisms and how they may be targeted for therapeutic intervention. He
Autor:
Tobias Alexander, John A. Snowden, Joachim Burman, Hyun-Dong Chang, Nicoletta Del Papa, Dominique Farge, James O. Lindsay, Florent Malard, Paolo A. Muraro, Rosamaria Nitti, Azucena Salas, Basil Sharrack, Mohamad Mohty, Raffaella Greco
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving as specific treatment for patients with severe and refractory autoimmune diseases (ADs), where mechanistic studies have provided evidence for a profound immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb612f883d98979c69f9707829f55e03
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459898
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459898
Autor:
Basil Sharrack, Raghda Barham, Duaa Abuarqoub, Abdalla Awidi, Ban Al-Kurdi, Ahmad M. Altantawi, Nidaa A. Ababneh, Dema Ali, Abdee T. Ryalat, Abdulla M. Alzibdeh, Asim N. Khanfar
Publikováno v:
Stem Cell Research, Vol 48, Iss, Pp 101925-(2020)
Ataxia with Oculomotor Apraxia Type 1 (AOA1) is an autosomal-recessive cerebellar ataxia characterized by early-onset cerebellar atrophy and axonal sensorimotor polyneuropathy. AOA1 is related to mutations in the aprataxin (APTX) gene encoding for th
Autor:
Laura Edwards, David Male, Basil Sharrack, Ignacio A. Romero, Helga E. de Vries, Camilla Cerutti
Publikováno v:
Cerutti, C, Edwards, L J, De Vries, H E, Sharrack, B, Male, D K & Romero, I A 2017, ' MiR-126 and miR-126∗ regulate shear-resistant firm leukocyte adhesion to human brain endothelium ', Scientific Reports, vol. 7, 45284 . https://doi.org/10.1038/srep45284
Scientific Reports, 7:45284. Nature Publishing Group
Scientific Reports
Scientific Reports, 7:45284. Nature Publishing Group
Scientific Reports
Leukocyte adhesion to brain endothelial cells, the blood-brain barrier main component, is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Leukocyte adhesion is mediated mainly by selectins, cell adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd0e1cc243baa938d81d59a5f550772
Autor:
Phil Williams, Ignacio A. Romero, Basil Sharrack, Radka Gromnicova, Simon C. Satchell, Mehmet Kaya, David Male
Publikováno v:
PLOS One
PLoS ONE, Vol 11, Iss 8, p e0161610 (2016)
PLoS ONE
Gromnicova, R, Kaya, M, Romero, I A, Williams, P, Satchell, S, Sharrack, B & Male, D 2016, ' Transport of gold nanoparticles by vascular endothelium from different human tissues ', PLoS ONE, vol. 11, no. 8, e0161610 . https://doi.org/10.1371/journal.pone.0161610
PLoS ONE, Vol 11, Iss 8, p e0161610 (2016)
PLoS ONE
Gromnicova, R, Kaya, M, Romero, I A, Williams, P, Satchell, S, Sharrack, B & Male, D 2016, ' Transport of gold nanoparticles by vascular endothelium from different human tissues ', PLoS ONE, vol. 11, no. 8, e0161610 . https://doi.org/10.1371/journal.pone.0161610
The selective entry of nanoparticles into target tissues is the key factor which determines their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which have tissue-specific properties. This study investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bac44539f4480ea2e19d3b06757718
Autor:
Simona Francese, Paul R. Heath, Basil Sharrack, M. Nicola Woodroofe, Natalie Rounding, Julie E. Simpson, Ruth H. Thomas, Rachel Waller, Paul G. Ince, Stephen B. Wharton, Alex Cudzich-Madry
Publikováno v:
Journal of neuroimmunology. 299
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). White matter lesions in MS are surrounded by areas of non-demyelinated normal appearing white matter (NAWM) with complex pathology, includi
Autor:
Ignacio A. Romero, Miguel Alejandro Lopez-Ramirez, Helga E. de Vries, Patricia Soblechero-Martín, David Male, Dongsheng Wu, Camilla Cerutti, Basil Sharrack
Publikováno v:
Cerutti, C 2016, ' MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro ', Fluids and Barriers of the CNS . https://doi.org/10.1186/s12987-016-0032-3
FLUIDS AND BARRIERS OF THE CNS, 13:8. BioMed Central
Cerutti, C, Soblechero-Martin, P, Wu, D, Lopez-Ramirez, M A, de Vries, H, Sharrack, B, Male, D K & Romero, I A 2016, ' MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro ', FLUIDS AND BARRIERS OF THE CNS, vol. 13, 8 . https://doi.org/10.1186/s12987-016-0032-3
Cerutti, C, Soblechero-Martin, P, Wu, D, Lopez-Ramirez, M A, de Vries, H, Sharrack, B, Male, D K & Romero, I A 2016, ' MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro ', Fluids and Barriers of the CNS, vol. 13, 8 . https://doi.org/10.1186/s12987-016-0032-3
Fluids and Barriers of the CNS
FLUIDS AND BARRIERS OF THE CNS, 13:8. BioMed Central
Cerutti, C, Soblechero-Martin, P, Wu, D, Lopez-Ramirez, M A, de Vries, H, Sharrack, B, Male, D K & Romero, I A 2016, ' MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro ', FLUIDS AND BARRIERS OF THE CNS, vol. 13, 8 . https://doi.org/10.1186/s12987-016-0032-3
Cerutti, C, Soblechero-Martin, P, Wu, D, Lopez-Ramirez, M A, de Vries, H, Sharrack, B, Male, D K & Romero, I A 2016, ' MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro ', Fluids and Barriers of the CNS, vol. 13, 8 . https://doi.org/10.1186/s12987-016-0032-3
Fluids and Barriers of the CNS
Background Increased leukocyte adhesion to brain endothelial cells forming the blood–brain barrier (BBB) precedes extravasation into the central nervous system (CNS) in neuroinflammatory diseases such as multiple sclerosis (MS). Previously, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88628ba4f8a120a59548841e3ce6c17a
https://kclpure.kcl.ac.uk/en/publications/d4c1c080-d636-4418-8aad-e36b9f2b0bb1
https://kclpure.kcl.ac.uk/en/publications/d4c1c080-d636-4418-8aad-e36b9f2b0bb1
Publikováno v:
Future Neurology. 6:521-530
Multiple sclerosis is a chronic immune-mediated disease of the CNS. Although it is a predominantly T-cell mediated condition, B cells and autoreactive antibodies play an important role in its pathogenesis, with the presence of oligoclonal immunoglobu
Autor:
Daniel Aeschlimann, Richard A. Grünewald, David S Sanders, N. Woodroofe, Marios Hadjivassiliou, Basil Sharrack
Publikováno v:
Acta Neurologica Scandinavica. 123:175-180
Background - The high prevalence of gluten sensitivity in patients with stiff-person syndrome (SPS) lead us to investigate the relationship between gluten sensitivity and GAD-antibody-associated diseases. Methods - We used ELISA assays for anti-GAD a