Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Anna Mae Diehl, Tianyi Chen
Publikováno v:
Hepatology
Acute liver damage causes hepatocyte stress and death, but in chronic liver disease impaired hepatocyte regeneration and immune cell infiltration prevents recovery. While the roles of both impaired liver regeneration and immune infiltration have been
Gut-microbiome-inflammation interactions have been linked to neurodegeneration in Alzheimer’s disease (AD) and other disorders. We hypothesized that treatment with rifaximin, a minimally absorbed gut-specific antibiotic, may modify the neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d58ad9f91d26fec40bbc761a4d35564a
https://doi.org/10.1101/2021.11.22.21266123
https://doi.org/10.1101/2021.11.22.21266123
Publikováno v:
The Liver
Autor:
Rajesh Kumar Dutta, Seh-Hoon Oh, Wen-Hsuan Yang, Jen-Tsan Ashley Chi, Kuo Du, Anna Mae Diehl, Tianai Sun
Publikováno v:
Liver Int
Background & aims The outcome of liver injury is dictated by factors that control the accumulation of myofibroblastic (activated) hepatic stellate cells (MF-HSCs) but therapies that specifically block this process have not been discovered. We evaluat
Liver is one of the few organs with immense regenerative potential even at adulthood in mammals. It is composed of primarily two cell types: hepatocytes and cholangiocytes, that can trans-differentiate to one another either directly or through interm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5749d0f1b1ec3c7f7913f7df6e5b49
https://doi.org/10.1101/2021.04.22.440352
https://doi.org/10.1101/2021.04.22.440352
Autor:
Brian B. Graham, Anna Mae Diehl, Marzena Swiderska-Syn, Kristen Robbins, Zhaoxing Pan, Shikha S. Sundaram, Kelley E. Capocelli, Ronald J. Sokol, Ann C. Halbower
Publikováno v:
Hepatology Communications, Vol 3, Iss 7, Pp 883-893 (2019)
Hepatology Communications
Hepatology Communications
Chronic intermittent hypoxia and hedgehog (Hh) pathway dysregulation are associated with nonalcoholic fatty liver disease (NAFLD) progression. In this study, we determined the relationship between obstructive sleep apnea (OSA)/nocturnal hypoxia and H
Autor:
C. Stephen Djedjos, Raul Aguilar Schall, Zachary Goodman, B. Mccolgan, G. Mani Subramanian, Anna Mae Diehl, Nezam H. Afdhal, Andrew J. Muir, Jaime Bosch, Vlad Ratziu, Zobair M. Younossi, Manal F. Abdelmalek, Arun J. Sanyal, Stephen H. Caldwell, Mitchell L. Shiffman, Catherine Jia, John G. McHutchison, Stephen A. Harrison, Robert P. Myers
Publikováno v:
Hepatology
Progression of nonalcoholic steatohepatitis (NASH) is incompletely characterized. We analyzed data on longitudinal changes in liver histology, hepatic venous pressure gradient (HVPG), and serum markers of fibrosis in 475 patients with NASH with bridg
Autor:
Michael Wagner, Justin P. Wright, Sharon Jiang, Thomas M. O’Connell, Lawrence A. David, Fátima C. Pereira, Anna Mae Diehl, Richard T. Premont, Tyler R. Kartzinel, David Berry, Anchi Wu, Arno Schintlmeister, Robert M. Pringle, Heather K. Durand, Robert R. Dunn, Xiyou Zhou, Aspen T. Reese, Susan C. Alberts, Laura P. Hale
Publikováno v:
Nature Microbiology
Nature microbiology
Nature microbiology
Resource limitation is a fundamental factor governing the composition and function of ecological communities. However, the role of resource supply in structuring the intestinal microbiome has not been established and represents a challenge for mammal
Autor:
Wing-Kin Syn, Keyur Patel, Cynthia D. Guy, Anna Mae Diehl, Robert D. Streilein, Ricardo Henao, Oliver Glass, Hans J Gruss, Manal F. Abdelmalek, Cynthia A. Moylan, Russell P. Hall
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
The severity of hepatic fibrosis is the primary predictor of liver‐related morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). Unfortunately, noninvasive serum biomarkers for NAFLD‐associated fibrosis are limited. W
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 22 (2020)
JCI Insight, Vol 5, Iss 22 (2020)
Adult liver has enormous regenerative capacity; it can regenerate after losing two-thirds of its mass while sustaining essential metabolic functions. How the liver balances dual demands for increased proliferative activity with maintenance of organ f