Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amanda B. Muir"'
Autor:
Amanda B. Muir, Jozef Madzo, Karami A, Hugh H. Huang, Kelsey Keith, Kathryn E. Hamilton, Murray Mg, Klochkova A, Mu A, Marie Pier Tetreault, Tatiana A. Karakasheva, Kelly A. Whelan, Jaroslav Jelinek, Kabir Mf, Saxena R, Cruz-Acuna R
Stratified squamous epithelium of the esophagus is comprised of basal keratinocytes that execute a terminal differentiation program in overlying suprabasal and superficial cell layers. Although morphologic progression coupled with expression of speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466a58736079a723cc38ac10bcd95315
https://doi.org/10.1101/2021.02.08.430312
https://doi.org/10.1101/2021.02.08.430312
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Autor:
Bailey Aaron, Masataka Shimonosono, Dominique Bailey, Takeo Hara, Julian A. Abrams, Kathryn E. Hamilton, Yuta Kasagi, Veronique Giroux, Hiroshi Nakagawa, Jonathan M. Spergel, Gary W. Falk, Amanda B. Muir, Tatiana A. Karakasheva, Seema S. Aceves, Kelly A. Whelan, Takashi Kijima, Benjamin J. Wilkins
Publikováno v:
Curr Protoc Stem Cell Biol
The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid ge
Autor:
Kelly A. Whelan, Benjamin J. Wilkins, Okan U. Elci, Evan S. Dellon, Gary W. Falk, Jonathan Gross, Bridget Godwin, Andres J. Klein-Szanto, Hiroshi Nakagawa, Jonathan M. Spergel, Maureen DeMarshall, Amanda B. Muir, Medha Sharma, Alain Benitez, Chris A. Liacouras
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Although eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are often disparities between patient-reported symptoms and eosinophil counts. We examined the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf01105763de1fa0d9d57e16578429
https://europepmc.org/articles/PMC7058491/
https://europepmc.org/articles/PMC7058491/
Autor:
Reshu Saxena, Mary Grace Murray, Tyler Beccari, Kelly A. Whelan, Julie Gang, Alena Klochkova, Andres J. Klein-Szanto, Amanda B. Muir, Mohammad Faujul Kabir
Publikováno v:
Gastroenterology. 158:S-185
Autor:
Masumi Wada, Masataka Shimonosono, Prasanna M. Chandramouleeswaran, Amanda B. Muir, Qiaosi Tang, Takashi Kijima, Hiroshi Nakagawa, Yuta Kasagi, Tatiana A. Karakasheva, Anil K. Rustgi, Kelly A. Whelan, Andres J. Klein-Szanto, Shoji Natsugoe
Publikováno v:
Gastroenterology. 156:S-107
Autor:
Anna J. Lee, Jonathan M. Spergel, Diana M. Lim, Eduardo Ruchelli, Alain Benitez, Amanda B. Muir, Mei-Lun Wang, Prasanna M. Chandramouleeswaran
Publikováno v:
Experimental Cell Research. 319:850-859
Background Esophageal fibrosis is a complication of eosinophilic esophagitis (EoE) which has been attributed to both subepithelial fibrosis and to epithelial to mesenchymal transition (EMT), a process by which epithelial cells acquire mesenchymal fea
Autor:
Alain Benitez, Benjamin J. Wilkins, Kara K. Dods, Jamie Merves, Jonathan M. Spergel, Jennifer H. Yearley, Yuliana Noah, Anna J. Lee, Mei-Lun Wang, Amanda B. Muir, Prasanna M. Chandramouleeswaran, Rene De Waal Malefyt, Fiona Gambanga, Sarit Toltzis, Hiroshi Nakagawa, Dawen Shen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150968 (2016)
PLoS ONE
PLoS ONE
Eosinophilic esophagitis (EoE) is a chronic Th2 and food antigen-mediated disease characterized by esophageal eosinophilic infiltration. Thymic stromal lymphopoetin (TSLP), an epithelial derived cytokine which bridges innate and Th2-type adaptive imm
Autor:
Glenn T. Furuta, Seema S. Aceves, Shaobo Guan, Lisa M. Fahey, Alain Benitez, Patrick M. A. Sleiman, Amanda B. Muir, Chris A. Liacouras, Jonathan M. Spergel, Prasanna M. Chandramouleeswaran, Hakon Hakonarson, Mei-Lun Wang, Antonella Cianferoni
Publikováno v:
Clinical and Translational Gastroenterology
Objectives TSLP has been shown to be associated with eosinophilic esophagitis (EoE). Specifically, children with EoE often have the nucleotides AA or AG instead of GG at the single nucleotide polymorphism position RS3806932. Presently, the phenotypic
Autor:
Hiroshi Nakagawa, Bridget Godwin, Kudakwashe R. Chikwava, Jianwen Que, Gary W. Falk, Andres J. Klein-Szanto, Koji Tanaka, Joanne C. Masterson, Kara K. Dods, Glenn T. Furuta, Mei-Lun Wang, Shahan D. Fernando, Amanda B. Muir, Prasanna M. Chandramouleeswaran, Kathryn E. Hamilton, Jamie Merves, Kelly A. Whelan, Veronique Giroux, Andy Guo, Jonathan M. Spergel, Eduardo Ruchelli, Alain Benitez
Publikováno v:
Gut. 66(7)
Objective The influence of eosinophilic oesophagitis (EoE)-associated inflammation upon oesophageal epithelial biology remains poorly understood. We investigated the functional role of autophagy in oesophageal epithelial cells (keratinocytes) exposed