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pro vyhledávání: '"Abdullahi Ibrahim Uba"'
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Publikováno v:
Computational Biology and Chemistry. 77:318-330
Histone deacetylase (HDAC) 6 plays a role in oncogenic transformation and cancer metastasis via tubulin deacetylation, making it a critical target for anticancer drug design. However, lack of selectivity shown by many of the current HDAC6 inhibitors
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Tubitak Directorate of Research and Development Resources of Kadir Has University Histone deacetylase (HDAC) 10 has been implicated in the pathology of various cancers and neurodegenerative disorders, making the discovery of novel inhibitors of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36768b405b51b233cae9a395da5432f7
https://hdl.handle.net/20.500.12469/3473
https://hdl.handle.net/20.500.12469/3473
Autor:
Abdullahi Ibrahim Uba, Kemal Yelekçi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:3231-3245
Histone deacetylases (HDACs) have gained increased attention as targets for anticancer drug design and development. HDAC inhibitors have proven to be effective for reversing the malignant phenotype in HDAC-dependent cancer cases. However, lack of sel
Autor:
Usman Muhammad Maigari, Sani Sharif Usman, Shariff Bilal Abdullahi, Bashir Abdullahi, Abdullahi Ibrahim Uba, Musa Dahiru
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 8, Pp e02214-(2019)
Heliyon, Vol 5, Iss 8, Pp e02214-(2019)
Background: Iron-deficiency anemia (IDA) or iron deficiency (ID) is by far the most common form of disorder affecting the cognitive development, physical growth and school performance of children in developing countries including Nigeria. Objectives:
Autor:
Abdullahi Ibrahim Uba, Kemal Yelekçi
Publikováno v:
Journal of biomolecular structuredynamics. 37(14)
Histone deacetylases (HDACs) are implicated in the pathology of various cancers, and their pharmacological blockade has proven to be promising in reversing the malignant phenotypes. However, lack of crystal structures of some of the human HDAC isofor
Publikováno v:
Journal of Biologically Active Products from Nature. 6:237-249
Angiotensin converting enzyme (ACE) plays an important physiological role in the regulation of blood pressure by converting angiotensin I to angiotensin II, a potent vasoconstrictor; hence, its inhibition is a major target in the prevention and treat
Publikováno v:
European Journal of Medicinal Plants. 11:1-7
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Publikováno v:
Volume: 41, Issue: 6 901-918
Turkish Journal of Biology
Turkish Journal of Biology
Histone deacetylases (HDACs) are enzymes that act on histone proteins to remove the acetyl group and thereby regulate the chromatin state. HDACs act not only on histone protein but also nonhistone proteins that are key players in cellular processes s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1397ea20f07f6656378a6bc3c4760c
https://europepmc.org/articles/PMC6375539/
https://europepmc.org/articles/PMC6375539/
Autor:
Abdullahi Ibrahim Uba, Musbahu M. Sani, Mustapha G Muhammad, Sani Sharif Usman, Umar S Abdussalam, Umar A. Abdullahi
Publikováno v:
Tropical Medicine & Surgery.
Gene mutation is a change in nucleotide sequence of DNA which results in an impaired or loss of functions of the associated gene. Mutation can occur spontaneously or be induced by mutagenic agent. It is considered deleterious when it affects the phen